GnRH agonists for Endometriosis and Fibroids: Understanding the Science, Interpreting the Evidence, and Applying the Guidelines

Speciality: Obstetrics & Gynaecology


Speaker:

PrakashHemne | Consultant Obstetrician & Gynaecologist

Description:

Welcome to our podcast on GnRH agonists for endometriosis and fibroids. GnRH agonists are medications that reduce oestrogen production, helping to manage symptoms like pain and heavy bleeding. The science behind them involves suppressing the pituitary gland, which in turn decreases hormone levels that drive the growth of endometrial and fibroid tissue. Evidence from clinical studies shows that GnRH agonists can significantly alleviate symptoms, but long-term use may lead to side effects such as bone loss. Current guidelines recommend using these medications for short-term relief, often alongside add-back therapy to minimise side effects. Always consult your healthcare provider to discuss personalised treatment options.

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