GnRH agonists for Endometriosis and Fibroids: Understanding the Science, Interpreting the Evidence, and Applying the Guidelines

Speciality: Obstetrics & Gynaecology


Speaker:

Mr. Dilip Kumar Sahu | Senior Consultant Gynaecologist

Description:

Welcome to our podcast on GnRH agonists for endometriosis and fibroids. GnRH agonists work by suppressing the production of oestrogen, which can help reduce pain and shrink fibroids. The science shows they’re effective, but side effects like hot flushes and bone loss need careful management. Evidence from clinical trials supports their short-term use, especially before surgery or when other treatments have failed. Guidelines recommend using these medications for limited periods, often alongside add-back therapy to minimise side effects. When considering GnRH agonists, a personalised approach is essential—balancing benefits, risks, and patient preferences. Always consult a healthcare professional for tailored advice.

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