GnRH agonists for Endometriosis and Fibroids: Understanding the Science, Interpreting the Evidence, and Applying the Guidelines

Speciality: Obstetrics & Gynaecology


Speaker:

A PARAMESHWAR GOUD | Endometriosis Specialist

Description:

Welcome to today’s episode, where we’re exploring the role of GnRH agonists in managing endometriosis and fibroids. GnRH agonists work by suppressing the production of ovarian hormones, effectively reducing symptoms like pelvic pain and heavy bleeding. Evidence shows these medications can provide significant symptom relief, especially for women who haven’t responded to first-line therapies. However, long-term use may lead to side effects such as bone loss, so treatment duration is often limited. Current guidelines recommend considering GnRH agonists as a second-line option, often alongside add-back therapy to minimise side effects. Always consult your healthcare provider to determine the best individual approach. Thanks for listening, and stay informed.

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