GnRH agonists for Endometriosis and Fibroids: Understanding the Science, Interpreting the Evidence, and Applying the Guidelines

Speciality: Obstetrics & Gynaecology


Speaker:

BALLE RAJASHEKAR | Fertility Specialist

Description:

Welcome to today’s episode, where we explore how GnRH agonists are used to manage endometriosis and fibroids. These medications work by reducing the body’s production of oestrogen, which helps shrink lesions and fibroids, and relieve symptoms like pain and heavy bleeding. Evidence supports their effectiveness for short-term symptom relief, but side effects such as bone loss and menopausal symptoms mean they’re usually prescribed for limited periods. Current guidelines recommend GnRH agonists when other treatments aren’t suitable or effective, often alongside add-back therapy to reduce side effects. If you or someone you know is considering this treatment, speak to a specialist to discuss the benefits and risks in your individual case.

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