GnRH agonists for Endometriosis and Fibroids: Understanding the Science, Interpreting the Evidence, and Applying the Guidelines

Speciality: Obstetrics & Gynaecology


Speaker:

Sachin Kadam | Senior Consultant Gynaecologist

Description:

Welcome to our podcast on GnRH agonists for endometriosis and fibroids. GnRH agonists are medications that temporarily lower oestrogen levels, helping to reduce pain and shrink fibroids. The science behind them centres on suppressing the hormonal signals responsible for tissue growth. Evidence shows they are effective for symptom relief, although they can have side effects like hot flushes and bone loss with long-term use. Guidelines recommend GnRH agonists mainly for short-term use, often as a bridge to surgery or when other treatments are not suitable. It’s important to discuss the benefits and risks with your healthcare provider to find the best approach for your individual needs.

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