Today's Updates

Baseline RV Dysfunction May predict Sotatercept response in PAH
Published Date: 05 Nov 2026

Baseline RV Dysfunction May predict Sotatercept response in PAH

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FDA Grants Priority Review to Huntington Disease Gene Therapy BLA Marco Meglio
Published Date: 05 Nov 2026

The FDA accepted uniQure's biologics license application for ifezuntirgene inilparvovec and granted it Priority Review, setting a target action date of May 1, 2027.

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On Beyond Seizures: Unmet Needs in Pediatric Epilepsy Clinics Susan Duberstein, MD
Published Date: 05 Nov 2026

Pediatric epilepsy care goes beyond seizures, addressing mental health, learning needs, coordinated referrals, equitable access, and smoother transition to adult services.

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Alzheimer Agent Sabirnetug Misses Primary Endpoint, Acumen Halts Development Marco Meglio
Published Date: 05 Nov 2026

Sabirnetug failed to meet its primary endpoint in Acumen Pharmaceuticals' phase 2 ALTITUDE-AD trial for early Alzheimer disease, prompting the company to end development.

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AL-S Pharma Details Planned Phase 3 Trial Design for AP-101 in ALS Marco Meglio
Published Date: 05 Nov 2026

AL-S Pharma outlined the design of AP101-03, a planned phase 3 trial of AP-101 in sporadic and SOD1-associated ALS, at the 2026 NEALS Annual Meeting.

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Brezosiran Demonstrates Mutant Huntingtin Reduction in Phase 1b Huntington Disease Study Louie Pasculli
Published Date: 05 Nov 2026

Alnylam Pharmaceuticals reported initial Phase 1b findings showing brezosiran reduced cerebrospinal fluid mutant huntingtin levels by a mean of 60% to 64% at 3 months, with plans for a pivotal study in 2027.

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NeuroVoices: Cindy Zadikoff, MD, MSc, on the FDA Approval of Tavapadon for Parkinson Disease Isabella Ciccone, MPH, Cindy Zadikoff, MD, MSc
Published Date: 05 Nov 2026

The executive medical director at AbbVie discussed the FDA approval of tavapadon, the first D1/D5 dopamine agonist for Parkinson disease, including the supporting TEMPO trial data and safety considerations.

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Bioengineered Vessel for Dialysis Access Integrates With Patient Cells
Published Date: 05 Nov 2026

Bioengineered Vessel for Dialysis Access Integrates With Patient Cells

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Bioengineered Vessel Adds 91 Catheter-Free Days for Women on Dialysis
Published Date: 05 Nov 2026

Bioengineered Vessel Adds 91 Catheter-Free Days for Women on Dialysis

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Clinician FAQ: Using Remibrutinib (Rhapsido) for Symptomatic Dermographism
Published Date: 05 Nov 2026

Clinician FAQ: Using Remibrutinib (Rhapsido) for Symptomatic Dermographism

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Cancer during young adulthood carries long-term mental toll, study finds

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In postmenopausal women with hormone receptor-positive tumors, obesity increases the risk of breast cancer recurrence.

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Surgery after EGFR TKI shows promise in prolonging progression-free survival in metastatic NSCLC

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Every cancer is different because of how evolution causes drug resistance and why various cancers require various treatments.

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Report: High risk of lung cancer from respirable crystalline silica even below the current occupational exposure limit



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