Today's Updates

Osimertinib's OS Benefit in Resected NSCLC Persists 8 Years
Published Date: 17 Sep 2026

Even years after treatment ends, adjuvant osimertinib brings an overall survival benefit to patients with resected EGFR-mutated lung cancer.

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Pelvic RT Tied to Longer Survival in Cervical Cancer
Published Date: 17 Sep 2026

In patients with newly diagnosed stage IVB cervical cancer, adding definitive-dose pelvic radiotherapy to chemotherapy was associated with longer survival compared with chemotherapy alone.

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New Data Put ADCs on the Map in Relapsed SCLC
Published Date: 17 Sep 2026

Two B7-H3-directed antibody-drug conjugates substantially improve survival over topotecan among patients with relapsed small cell lung cancer — pointing to a potential new treatment class.

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Real-World Liso-Cel Results in MCL Consistent With Trials
Published Date: 17 Sep 2026

Two analyses of liso-cel CAR T-cell therapy in relapsed or refractory mantle cell lymphoma show response rates in the real-world setting similar to those seen in clinical trial populations.

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Antibiotic Use in Hospice Linked to Higher Mortality Risk
Published Date: 17 Sep 2026

Antibiotic use in patients under hospice care is associated with an increased risk for mortality; for infectious hospice-qualifying conditions, antibiotic use is linked to extended survival.

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Latest News

One Active Joint Left in Inflammatory Arthritis: What to Do?

Despite being a clinical scenario familiar to any rheumatologist, little evidence exists to guide treatment decisions for inflammatory arthritis limited to a single major joint.

AbbVie's Blood Cancer Therapy Lowers Disease Progression, Death Risk in Trial

AbbVie said on Thursday its therapy for a type of blood cancer has improved patients' response rate ⁠to treatment and reduced the risk of disease progression or death,...

Less Frequent Monitoring May Be Safe in Patients on MTX

For patients on methotrexate, routine monitoring every 6 months vs 3 months is not linked to an increase in laboratory or blood count abnormalities.

Gout Tied to Elevated Fracture Risk; Drug Adherence Helps

A recent diagnosis of gout is associated with an increased risk for fractures, and high adherence to allopurinol may help mitigate this elevated risk.

BMI Affects Response to JAK Inhibitors in RA

A higher BMI is associated with a reduced response to JAK inhibitors in patients with rheumatoid arthritis.

Meet the Doctor for the New York Knicks

A Q&A with Daphne Scott

Aspirin Alone Gets the Job Done for Clot Prevention After Joint Surgery

Regimens may drop the direct anticoagulants for some patients, based on EPCAT III

Knee Pain? Ragged Cartilage? Research Suggests Surgery's Not the Best Answer

And it might make things worse

Astronauts Obtain First X-Rays in Space

Portable radiography system could improve diagnostic capabilities for crew health

Surfing Lesson Ends With Unusual Injury

Physician warns it's better to sit on the board while waiting for a wave

Same Knee Surgery, Twice the Price: Hospital Monopolies Push Up Healthcare Costs

How large hospital systems can dominate the competition

Osteoarthritis of the Big Toe? Don't Wait to Operate

Randomized trial favors surgery over "watchful waiting"

Tommy John Dies; Fauci Called Again to Testify; Vasculitis Drug Pulled in Europe

Health news and commentary gathered by MedPage Today staff

Are HYROX Athletes Overdoing It?

Survey finds injuries are common in this rapidly growing fitness challenge

Rare Case of Multiple Myeloma in Teenage Girl

Successful use of affordable induction therapy with autologous stem cell transplantation

Multi-Joint Arthritis Bodes Poorly for Healthy Aging

Osteoarthritis extent tied to increased frailty, even after adjusting for physical activity

Latest News

One Active Joint Left in Inflammatory Arthritis: What to Do?

Despite being a clinical scenario familiar to any rheumatologist, little evidence exists to guide treatment decisions for inflammatory arthritis limited to a single major joint.

AbbVie's Blood Cancer Therapy Lowers Disease Progression, Death Risk in Trial

AbbVie said on Thursday its therapy for a type of blood cancer has improved patients' response rate ⁠to treatment and reduced the risk of disease progression or death,...

Less Frequent Monitoring May Be Safe in Patients on MTX

For patients on methotrexate, routine monitoring every 6 months vs 3 months is not linked to an increase in laboratory or blood count abnormalities.

Gout Tied to Elevated Fracture Risk; Drug Adherence Helps

A recent diagnosis of gout is associated with an increased risk for fractures, and high adherence to allopurinol may help mitigate this elevated risk.

BMI Affects Response to JAK Inhibitors in RA

A higher BMI is associated with a reduced response to JAK inhibitors in patients with rheumatoid arthritis.

Meet the Doctor for the New York Knicks

A Q&A with Daphne Scott

Aspirin Alone Gets the Job Done for Clot Prevention After Joint Surgery

Regimens may drop the direct anticoagulants for some patients, based on EPCAT III

Knee Pain? Ragged Cartilage? Research Suggests Surgery's Not the Best Answer

And it might make things worse

Astronauts Obtain First X-Rays in Space

Portable radiography system could improve diagnostic capabilities for crew health

Surfing Lesson Ends With Unusual Injury

Physician warns it's better to sit on the board while waiting for a wave

Same Knee Surgery, Twice the Price: Hospital Monopolies Push Up Healthcare Costs

How large hospital systems can dominate the competition

Osteoarthritis of the Big Toe? Don't Wait to Operate

Randomized trial favors surgery over "watchful waiting"

Tommy John Dies; Fauci Called Again to Testify; Vasculitis Drug Pulled in Europe

Health news and commentary gathered by MedPage Today staff

Are HYROX Athletes Overdoing It?

Survey finds injuries are common in this rapidly growing fitness challenge

Rare Case of Multiple Myeloma in Teenage Girl

Successful use of affordable induction therapy with autologous stem cell transplantation

Multi-Joint Arthritis Bodes Poorly for Healthy Aging

Osteoarthritis extent tied to increased frailty, even after adjusting for physical activity

News All Time

Can Creatine Help Non-Athletes? A Physical Therapist Weighs In

Creatine may have less risk than other supplements, but who might benefit is unclear

Synovitis Confirmed as Prognostic in Hand Osteoarthritis, Regardless of Subtype

— Doesn't matter whether it's in the first carpometacarpal or interphalangeal joints

Denosumab May Protect Joints in Adults With Osteoporosis

Starting denosumab is associated with a modestly lower risk of developing osteoarthritis than starting oral bisphosphonates among adults with osteoporosis.

Straight Talk on Scoliosis Screening in Primary Care

Pediatricians can and should screen for scoliosis, especially in teens who are still growing.

Real-World Strategies to Improve Multidisciplinary Care Coordination of TGCT

Real-World Strategies to Improve Multidisciplinary Care Coordination of TGCT

Real-World Strategies to Improve Multidisciplinary Care Coordination of TGCT

Real-World Strategies to Improve Multidisciplinary Care Coordination of TGCT

Did Your Patient’s Cane Kill Them?

Mobility assistance devices may be harmful if not prescribed properly

Trial Casts Doubt on Antibiotics for Refractory Low Back Pain

Now it's up to clinicians to sort out conflicting evidence

GLP-1 Drugs Tied to Lower Need for Knee Replacement

But what drives the apparent effect remains unknown. Is it the weight loss or other factors?

Top Pro Athletes Credit a Tiny New Scope for Their Faster Recoveries

There's little published research, but a small, flexible arthroscope is accumulating proponents

Cancer Diagnosis Delays During Screening Study; Benefits of Resistance Training

Also in TTHealthWatch: GLP-1 agonists and knee replacement

Woman's Ice-Skating Fall Produces Striking X-Ray, Rare Forearm Break

While Monteggia fracture is uncommon in adults, early intervention is crucial

The World Cup Is a Celebration of Sport. It's Also a Warning About Climate Change.

The tournament is a preview for how outdoor activities are being reshaped globally

Why Some 'Old' Soccer Players Like Messi, Ronaldo Can Still Kick It in the World Cup

Advancements in training and recovery means elite athletes are playing longer than ever before

FDA Declines to Approve Sobi's Gout Therapy on Concerns Over Manufacturing

The U.S. Food and Drug Administration declined to approve Swedish drugmaker Sobi's therapy to treat uncontrolled ⁠gout, a common form of inflammatory arthritis, the company...

Optimizing the Use of Disease-Modifying Therapies Across the Spinal Muscular Atrophy Care Continuum: An Expert TheraTalk

Optimizing the Use of Disease-Modifying Therapies Across the Spinal Muscular Atrophy Care Continuum: An Expert TheraTalk

Recommended News For You

Gene therapies for BCG-unresponsive bladder cancer have high response rates.

A researcher has found that yoga exhibits the "most improvement" in helping long-term cancer survivors restore their brain health.

Vapers May Be Less Likely to Undergo Lung Cancer Screening

PSA Testing Is Not Enough for Another Candidate for Prostate Cancer Screening.

Germline Variants Predict Lobular Breast Cancer Recurrence

Chronic stress and obesity work together to accelerate pancreatic cancer development and growth, study finds

Oncologist Sued for Double-Billing; Pharmacy Deserts; 'She Loved Scotch and Pizza'

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