Today's Updates

Episode 2: Diagnosing and Managing Cushing Syndrome
Published Date: 20 Apr 2026

Drs Marwah Abdalla and Lewis Blevins discuss Cushing syndrome: Why it is frequently missed, how clinicians can screen for it, and how to manage it.

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MASLD for Cardiologists
Published Date: 20 Apr 2026

An overview of MASLD, including the epidemiology, diagnostic approaches, and therapeutic options highlighting the cardiologists’ role in its multidisciplinary management.

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Jan 30 2026 This Week in Cardiology
Published Date: 20 Apr 2026

Listener feedback, huge news in the rapidly expanding world of PFA AF Ablation, obesity, and a beautiful trial studying an AI-enhanced diagnostic tool in the office are the topics discussed by John Mandrola, MD, in this week’s podcast.

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Exogenous Ketones and Exercise Tolerance: KETO-HFpEF
Published Date: 20 Apr 2026

A crossover trial to determine whether ketone ester improves exercise tolerance in HFpEF.

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Feb 06 2026 This Week in Cardiology
Published Date: 20 Apr 2026

Problems with the PREVENT score, a breakthrough in lipid-lowering therapy, a surprising benefit in stroke care, and more thoughts on statins and preventive care of heart disease are the topics John Mandrola, MD, discusses in this week’s podcast.

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Frailty in CVD: Time for a Universal Definition!
Published Date: 20 Apr 2026

Citing The Death of Ivan Ilyich, the authors call for professional societies to jointly embrace a core definition of frailty for cardiovascular care and clinical practice.

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Immunotherapy Combo Shows Promise for Hodgkin Lymphoma
Published Date: 20 Apr 2026

A phase 2 study evaluates the safety and efficacy of brentuximab vedotin and nivolumab plus chemotherapy in patients with early-stage classical Hodgkin lymphoma.

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Nut Consumption Linked to Improved Sperm Quality
Published Date: 20 Apr 2026

A Spanish cross-sectional study of 222 men finds that those with the highest nut intake have higher sperm counts and 75% lower odds of abnormal motility, especially among men adhering to a Mediterranean diet.

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Latest News

Beta-Blocker Use After Myocardial Infarction: When to Stop?

New trial data question routine long term beta blocker use after myocardial infarction in stable patients with preserved function, prompting reassessment of continuation decisions.

Ready or Not, LLMs Are Coming for Medicine

Current chatbots might show deficiencies in clinical reasoning for now, but don’t hold your breath.

SGO 2026

Read clinically focused news coverage of key developments from SGO 2026

Apr 10 2026 This Week in Cardiology

Three imaging-guided PCI trials (two with surprising results), LDL targets, an oral PCSK9 inhibitor, and another beta-blocker withdrawal trial are the topics John Mandrola, MD, discusses in this week’s podcast.

When Binge Eating Becomes an Emergency

A single binge episode may precipitate acute gastric dilatation, a rare but life-threatening condition that clinicians can easily miss.

New Lipid Guidelines: A User’s Guide

Cardiologist Michelle O’Donoghue interviews the lead author of the latest ACC/AHA guidelines for the management of dyslipidemia.

How to Approach Incidental Findings on Abdominal Imaging

High resolution imaging often finds incidental abdominal lesions; high quality characterization and risk stratification avoid unnecessary tests and treat those with significant malignancy risk.

Don’t Sign Yet: What’s in Your Physician Agreement?

Don’t rely on verbal promises. Healthcare attorney Ericka Adler explains what physicians must get in writing before signing a physician agreement.

BCR in Prostate Cancer: What It Means and What Comes Next

Biochemical recurrence is one of the most challenging scenarios in prostate cancer care. Dr David Einstein explores how clinicians interpret rising PSA levels and highlights management strategies.

Mandrola’s Top 4 Trials from ACC 2026

Trials on Impella in high-risk PCI, percutaneous left atrial appendage closure, CTO-PCI, and spironolactone in HFpEF are Mandrola’s most anticipated at the upcoming 2026 ACC meeting in New Orleans.

US FDA Extends Review Of Lantheus' Diagnostic Imaging Kit by Three Months

Lantheus Holdings said on Tuesday that the U.S. health regulator has extended its review of the ⁠company's diagnostic imaging kit by three months as it needs more time to...

Can AI Restore the Power of the Stethoscope?

New trials show AI can identify serious cardiac disease from heart sounds alone, yet technology only changes outcomes when clinicians trust it and use it consistently.

Erectile Dysfunction in Young Man Reveals Prolactinoma

A laboratory abnormality during the evaluation of erectile dysfunction in a young man leads clinicians to identify hyperprolactinemia and a pituitary tumor on MRI.

Incidentalomas and Anxiety in Whole-Body Screening

Dr Bishal Gyawali discusses the rising trend of whole-body scans for cancer screening and how they can cause more harm than good.

Enhancing Shared Decision-Making in Early Breast Cancer

Experts discuss communication approaches that enhance shared decision-making for patients with early breast cancer, spanning surgery, adjuvant therapy, and survivorship.

Bannwarth Syndrome in a Woman With Early Breast Cancer

The case emphasizes Bannwarth syndrome as a rare but treatable cause of neurologic deterioration in an older woman receiving surgical cancer care.

Latest News

Beta-Blocker Use After Myocardial Infarction: When to Stop?

New trial data question routine long term beta blocker use after myocardial infarction in stable patients with preserved function, prompting reassessment of continuation decisions.

Ready or Not, LLMs Are Coming for Medicine

Current chatbots might show deficiencies in clinical reasoning for now, but don’t hold your breath.

SGO 2026

Read clinically focused news coverage of key developments from SGO 2026

Apr 10 2026 This Week in Cardiology

Three imaging-guided PCI trials (two with surprising results), LDL targets, an oral PCSK9 inhibitor, and another beta-blocker withdrawal trial are the topics John Mandrola, MD, discusses in this week’s podcast.

When Binge Eating Becomes an Emergency

A single binge episode may precipitate acute gastric dilatation, a rare but life-threatening condition that clinicians can easily miss.

New Lipid Guidelines: A User’s Guide

Cardiologist Michelle O’Donoghue interviews the lead author of the latest ACC/AHA guidelines for the management of dyslipidemia.

How to Approach Incidental Findings on Abdominal Imaging

High resolution imaging often finds incidental abdominal lesions; high quality characterization and risk stratification avoid unnecessary tests and treat those with significant malignancy risk.

Don’t Sign Yet: What’s in Your Physician Agreement?

Don’t rely on verbal promises. Healthcare attorney Ericka Adler explains what physicians must get in writing before signing a physician agreement.

BCR in Prostate Cancer: What It Means and What Comes Next

Biochemical recurrence is one of the most challenging scenarios in prostate cancer care. Dr David Einstein explores how clinicians interpret rising PSA levels and highlights management strategies.

Mandrola’s Top 4 Trials from ACC 2026

Trials on Impella in high-risk PCI, percutaneous left atrial appendage closure, CTO-PCI, and spironolactone in HFpEF are Mandrola’s most anticipated at the upcoming 2026 ACC meeting in New Orleans.

US FDA Extends Review Of Lantheus' Diagnostic Imaging Kit by Three Months

Lantheus Holdings said on Tuesday that the U.S. health regulator has extended its review of the ⁠company's diagnostic imaging kit by three months as it needs more time to...

Can AI Restore the Power of the Stethoscope?

New trials show AI can identify serious cardiac disease from heart sounds alone, yet technology only changes outcomes when clinicians trust it and use it consistently.

Erectile Dysfunction in Young Man Reveals Prolactinoma

A laboratory abnormality during the evaluation of erectile dysfunction in a young man leads clinicians to identify hyperprolactinemia and a pituitary tumor on MRI.

Incidentalomas and Anxiety in Whole-Body Screening

Dr Bishal Gyawali discusses the rising trend of whole-body scans for cancer screening and how they can cause more harm than good.

Enhancing Shared Decision-Making in Early Breast Cancer

Experts discuss communication approaches that enhance shared decision-making for patients with early breast cancer, spanning surgery, adjuvant therapy, and survivorship.

Bannwarth Syndrome in a Woman With Early Breast Cancer

The case emphasizes Bannwarth syndrome as a rare but treatable cause of neurologic deterioration in an older woman receiving surgical cancer care.

News All Time

Can Large Language Models Simplify Radiology Reports?

A meta-analysis suggests that large language model-simplified radiology reports improve patient understanding and readability while preserving high accuracy and completeness.

NPH: What You Learned in Med School Is Wrong

Neurologists Indu Subramanian and Alfonso Fasano discuss normal pressure hydrocephalus and why some of the classic dogma about this condition is wrong.

Promoting Whole-Body Imaging: Not There Yet

Ethicist Art Caplan discusses marketing promotions for expensive whole-body imaging.

Medicine Will Turn Cellular Age Backward by 2050: Barzilai

Aging may not be permanent. Nir Barzilai explains how human cells reset to zero and why partial rejuvenation could be possible within decades.

Adding to the Toolbox: Thyroid Artery Embolization

Drs Kaniksha Desai and Juan Camacho discuss thyroid artery embolization.

The Time Burden of Cancer Treatment

Dr Kathy Miller discusses a recent study quantifying the hidden time burden of cancer care and its impact on clinic operations and patient experience.

ASCO GI: Updates in Pancreatic, Gastric, CRC

Dr Emil Lou highlights practice-changing updates from ASCO GI, including new immunotherapy, targeted therapy, and circulating tumor DNA advances across gastrointestinal cancers.

High-speed imaging tracks live brain cell activity in awake mice

A research team from the School of Engineering at The Hong Kong University of Science and Technology (HKUST) has achieved a breakthrough in brain imaging by developing the world's first technology to capture high-resolution ...

Study highlights AI limits in heart care

There are limits in applying AI to images of the heart, according to a new study from the Smidt Heart Institute at Cedars-Sinai published in the Journal of the American Society of Echocardiography.

New material may outperform current agents used in medical imaging

Scientists at Oregon State University have filed a patent on a design for a new magnetic resonance imaging contrast agent with the potential to outperform current agents while being less toxic to patients and more environmentally ...

Imaging technique maps the brain's nerve fiber labyrinth with micrometer precision

In order to understand brain diseases, neuroscientists try to untangle the intricate nerve fiber labyrinth of our brain. Before analyzing brain tissue under a microscope, it is often soaked in paraffin wax to achieve high-quality ...

New brain atlas offers unprecedented detail in MRI scans

A new AI-assisted brain atlas that can help visualize the human brain in unprecedented detail has been developed by UCL researchers, in a major step forward for neuroscience and neuroimaging.

Holographic optogenetics could enable faster brain mapping for new discoveries

Recent technological advances have opened new possibilities for neuroscience research, allowing researchers to map the brain's structure and synaptic connectivity (i.e., the junctions via which neurons communicate with each ...

New method noninvasively measures Achilles tendon structure and function in professional dancers

A study in the Journal of Orthopaedic Research uses a noninvasive, nonradioactive imaging-based method to measure the structure and function of the Achilles tendon in professional ballet dancers. The method could potentially ...

MRI-based evaluation system accurately quantifies paraspinal muscle atrophy and nerve root injury severity

A noninvasive MRI technique that measures volumetric changes in paraspinal muscles could transform how doctors assess nerve damage in the cervical spine, which helps guide more precise treatment decisions and potentially ...

Surgery may not be required for some breast lesions, research suggests

Researchers at King's have found that certain breast lesions identified during routine screening may not always require removal. The findings could help reduce unnecessary procedures while maintaining high standards of patient ...

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