Today's Updates

Lacosamide Displays Positive Efficacy and Safety in Phase 2 Clinical Trial of Neonatal Seizures Louie Pasculli
Published Date: 10 Dec 2025

Findings from a phase 2 trial highlighted lacosamide's effectiveness and safety in treating neonatal seizures, showing significant seizure reduction and tolerability in patients.

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This Week on NeurologyLive® — December 8, 2025 Isabella Ciccone, MPH
Published Date: 10 Dec 2025

Here's some of what is coming soon to NeurologyLive® this week.

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GABA-AT Inhibitor OV329 Shows Safety, Preliminary Target Engagement in Phase 1 Study Marco Meglio
Published Date: 10 Dec 2025

Ovid Therapeutics' OV329 shows promise as a safe, effective GABA-AT inhibitor for treating drug-resistant seizures, with strong phase 1 trial results.

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Microbiota Restoration Therapy: A New Era in C. difficile Management, With Paul Feuerstadt, MD Paul Feuerstadt, MD
Published Date: 10 Dec 2025

FDA-approved RBL shows 95% success and sustained microbiome restoration in recurrent C. difficile.

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5 Pulmonology Headlines You Missed in November 2025
Published Date: 10 Dec 2025

5 Pulmonology Headlines You Missed in November 2025

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Adjunctive Lumateperone Significantly Improves MDD Symptoms by Day 43
Published Date: 10 Dec 2025

Adjunctive Lumateperone Significantly Improves MDD Symptoms by Day 43

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Stage 5 CKD May Reverse Female Survival Advantage
Published Date: 10 Dec 2025

Stage 5 CKD May Reverse Female Survival Advantage

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HS Specialists Express Support for Earlier Use of Biologics Among Patients
Published Date: 10 Dec 2025

HS Specialists Express Support for Earlier Use of Biologics Among Patients

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Dupilumab Superior in Analysis of Monoclonal Antibodies for Atopic Dermatitis
Published Date: 10 Dec 2025

Dupilumab Superior in Analysis of Monoclonal Antibodies for Atopic Dermatitis

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Potential Causal Relationship Identified Between Depression, Psoriasis
Published Date: 10 Dec 2025

Potential Causal Relationship Identified Between Depression, Psoriasis

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Latest News

6 Ophthalmology Headlines You Missed in October 2025

6 Ophthalmology Headlines You Missed in October 2025

New Parameters for Faster Geographic Atrophy Progression Established, with Srinivas Sadda, MD Srinivas Sadda, MD

The pooled sham cohorts of the OAKS and DERBY trials have revealed a series of indicators for faster geographic atrophy lesion growth.

OCU-410 Gene Therapy Preserves Visual Acuity and Slows GA Lesion Progression, with Jay Chhablani, MD Jay Chhablani, MD

Recent phase 1/2 trial data indicate the safety and efficacy of the surgical, subretinal injection in monitoring cellular homeostasis.

Intravitreal UBX1325 Shows Efficacy in Diabetic Retinopathy, DME, with Dante Pieramici, MD Dante J. Pieramici, MD

Results from the BEHOLD and ASPIRE trials indicate the long lasting effects of UBX1325 in improving retinal function and structure.

Q3 2025 Recap: Ophthalmology News and Updates Ryan Livingston

The Q3 recap for ophthalmology spotlights major FDA decisions and major clinical trial updates in a variety of diseases.

Correlation Between Diabetes and Risk of Uveitis Confirmed in Recent Study Ryan Livingston

In addition to type 1 and 2 diabetes, diabetic retinopathy substantially increases the risk of developing and worsening uveitis.

Psoriasis Associated with Risk of Age-Related Macular Degeneration Ryan Livingston

Based on 3 propensity-matched control groups, patients with psoriasis can have anywhere from a 40% to 56% higher risk.

FDA Approves Adalimumab-aaty (Yuflyma) Pediatric Indications in Hidradenitis Suppurativa, Uveitis Abigail Brooks, MA

The FDA approved expanded indications for adalimumab-aaty (Yuflyma) and its unbranded version to include the treatment of adolescent HS and pediatric UV.

FDA Approves Incision-Free Topical Therapy Epioxa for Keratoconus Ryan Livingston

This approval represents an alternative method for approaching this undertreated disease, shortening recovery while minimizing invasiveness.

Dyslipidemia May Delay Macular Hole Closure After Surgery Ryan Livingston

A recent study highlights correlations between later healing, triglyceride levels, and total cholesterol in patients receiving MH.

GLP-1 RAs May Influence Development of Nonexudative AMD in Patients With Obesity Ryan Livingston

Although no direct correlation can be drawn, these findings suggest a possible ocular benefit from GLP-1 RAs compared to other weight loss drugs.

Brolucizumab Outperforms Aflibercept in DME Regardless of Prior Treatment

Brolucizumab Outperforms Aflibercept in DME Regardless of Prior Treatment

Outlook Therapeutics Resubmits Biologics License Application for ONS-5010 for Wet AMD

Outlook Therapeutics Resubmits Biologics License Application for ONS-5010 for Wet AMD

Temporal artery ultrasound in the real-time diagnosis of stroke of the eye

For most of us, the phrase "stroke of the eye" sounds like a metaphor. But for UK HealthCare's Jagannadha "Jay" Avasarala, M.D., Ph.D., it's a literal and urgent diagnosis—one that could mean the difference between sight ...

Demystifying a visual illusion: Why we see color that's not there

A new discovery has unraveled why we sometimes see colors that aren't there. The phenomenon of "color afterimages" is when you see illusory—or false—colors after staring at real colors for a longer time. Through this, ...

Childhood blindness: Recommended realignment of prevention, medical treatment in development cooperation

International health policy and German development cooperation focus primarily on preventive measures. This is evident, for example, in diseases such as childhood blindness, which can be prevented through vaccinations or ...

Latest News

6 Ophthalmology Headlines You Missed in October 2025

6 Ophthalmology Headlines You Missed in October 2025

New Parameters for Faster Geographic Atrophy Progression Established, with Srinivas Sadda, MD Srinivas Sadda, MD

The pooled sham cohorts of the OAKS and DERBY trials have revealed a series of indicators for faster geographic atrophy lesion growth.

OCU-410 Gene Therapy Preserves Visual Acuity and Slows GA Lesion Progression, with Jay Chhablani, MD Jay Chhablani, MD

Recent phase 1/2 trial data indicate the safety and efficacy of the surgical, subretinal injection in monitoring cellular homeostasis.

Intravitreal UBX1325 Shows Efficacy in Diabetic Retinopathy, DME, with Dante Pieramici, MD Dante J. Pieramici, MD

Results from the BEHOLD and ASPIRE trials indicate the long lasting effects of UBX1325 in improving retinal function and structure.

Q3 2025 Recap: Ophthalmology News and Updates Ryan Livingston

The Q3 recap for ophthalmology spotlights major FDA decisions and major clinical trial updates in a variety of diseases.

Correlation Between Diabetes and Risk of Uveitis Confirmed in Recent Study Ryan Livingston

In addition to type 1 and 2 diabetes, diabetic retinopathy substantially increases the risk of developing and worsening uveitis.

Psoriasis Associated with Risk of Age-Related Macular Degeneration Ryan Livingston

Based on 3 propensity-matched control groups, patients with psoriasis can have anywhere from a 40% to 56% higher risk.

FDA Approves Adalimumab-aaty (Yuflyma) Pediatric Indications in Hidradenitis Suppurativa, Uveitis Abigail Brooks, MA

The FDA approved expanded indications for adalimumab-aaty (Yuflyma) and its unbranded version to include the treatment of adolescent HS and pediatric UV.

FDA Approves Incision-Free Topical Therapy Epioxa for Keratoconus Ryan Livingston

This approval represents an alternative method for approaching this undertreated disease, shortening recovery while minimizing invasiveness.

Dyslipidemia May Delay Macular Hole Closure After Surgery Ryan Livingston

A recent study highlights correlations between later healing, triglyceride levels, and total cholesterol in patients receiving MH.

GLP-1 RAs May Influence Development of Nonexudative AMD in Patients With Obesity Ryan Livingston

Although no direct correlation can be drawn, these findings suggest a possible ocular benefit from GLP-1 RAs compared to other weight loss drugs.

Brolucizumab Outperforms Aflibercept in DME Regardless of Prior Treatment

Brolucizumab Outperforms Aflibercept in DME Regardless of Prior Treatment

Outlook Therapeutics Resubmits Biologics License Application for ONS-5010 for Wet AMD

Outlook Therapeutics Resubmits Biologics License Application for ONS-5010 for Wet AMD

Temporal artery ultrasound in the real-time diagnosis of stroke of the eye

For most of us, the phrase "stroke of the eye" sounds like a metaphor. But for UK HealthCare's Jagannadha "Jay" Avasarala, M.D., Ph.D., it's a literal and urgent diagnosis—one that could mean the difference between sight ...

Demystifying a visual illusion: Why we see color that's not there

A new discovery has unraveled why we sometimes see colors that aren't there. The phenomenon of "color afterimages" is when you see illusory—or false—colors after staring at real colors for a longer time. Through this, ...

Childhood blindness: Recommended realignment of prevention, medical treatment in development cooperation

International health policy and German development cooperation focus primarily on preventive measures. This is evident, for example, in diseases such as childhood blindness, which can be prevented through vaccinations or ...

News All Time

Better vision test enables precise detection of eye disorders in toddlers

The development of a new tool for testing the eyesight of children under three could mean more children receive treatment for vision difficulties earlier, leading to positive effects on learning and development.

Eye scans reveal clues to aging and heart disease risk, study finds

The tiny blood vessels in your eyes might hold the key to predicting a person's risk of developing heart disease and how fast they're biologically aging, according to researchers at McMaster University and Population Health ...

LASIK armed with 3D eye model provides better vision correction

An advanced form of LASIK (Laser-Assisted In-Situ Keratomileusis) eye surgery that uses a virtual 3D model of a person's eye appears to offer patients better vision, a new study says.

Fancy dress contact lenses can cause infections, ulcers, even blindness—how to keep your eyes safe this Halloween

With Halloween just around the corner, thousands will be shopping for fancy dress contact lenses to go with their costume. The appeal is clear, as their endless colors and shapes allow you to radically change how you look—who ...

Cataract surgery becoming an in-office procedure, experts say

Imagine popping by your eye doctor's office for a quick cataract surgery.

Age-related macular degeneration: Robot delivers ultra-precision injections with rapid setup times

Many surgeons admit that medical robots can now operate with greater precision than human specialists. However, the complex preparation required for robotic surgery still takes far too long. But a new robotic assistant for ...

Risk of eye disease increases during menopause transition

Many symptoms, such as hot flashes and vaginal dryness, are commonly associated with the menopause transition. One of the lesser-known symptoms that worsens in midlife is dry eyes. A new study suggests that postmenopausal ...

Like radar, a brain wave sweeps a cortical region to read out information held in working memory

Imagine you are a security guard in one of those casino heist movies where your ability to recognize an emerging crime will depend on whether you notice a subtle change on one of the many security monitors arrayed on your ...

Transformative eye research expands donor pool for corneal transplant patients

Many eye banks won't accept corneas from donors with diabetes, concerned they might be harder to prepare for transplant surgery or are more likely to fail.

Pickleball popularity surge serves up spike in serious eye injuries

Rutgers New Jersey Medical School-led researchers have identified a striking rise in pickleball-related eye injuries among players visiting emergency departments across the United States. Using two decades of national surveillance ...

Patient wealth is associated with quality of glaucoma care

Patients with newly diagnosed glaucoma who have less wealth or reside in rural communities are less likely to receive standard glaucoma care compared to wealthier patients, according to a recent multi-institutional study ...

Vision therapy reverses concussion-related double and blurred vision, study finds

Nearly half of adolescents and young adults with lingering symptoms of concussion suffer from eye coordination disorders that cause double and blurred vision, headaches and difficulties concentrating.

FDA authorizes Essilor Stellest eyeglass lenses for children with myopia

The U.S. Food and Drug Administration has authorized marketing of the Essilor Stellest eyeglass lenses to correct myopia, with or without astigmatism, and to slow the progression of the disease in children 6 to 12 years old.

Bringing eye images into focus with AI

Researchers at the University of Waterloo have developed a better way to enhance the clarity and detail of eye images used to diagnose disease by teaching artificial intelligence (AI) software the science behind the imaging ...

Polyunsaturated fatty acid therapy reverses age-related vision decline in mice

Changes in vision are often a common sign of aging. But what if we could reverse age-related visual decline? In a new study, UC Irvine researchers explore a possible therapy for addressing "aging" in the eye and for preventing ...

AI at the eyelid: Glasses that track health through your blinks

Penn researchers have developed an AI-powered device that turns ordinary glasses into a smart, energy-efficient health monitor by watching you blink.

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