Today's Updates

Weighing Bleeding Risk in Pulmonary Embolism, With Samantha Pettigrew, MD Samantha Pettigrew, MD
Published Date: 28 Oct 2026

At CHEST 2026, Pettigrew reviewed STRATIFY and STORM-PE data, citing bleeding risk with low-dose alteplase and 90-day walk gains with thrombectomy.

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AI and Emerging Technologies in COPD Care, With Jean Bourbeau, MD Jean Bourbeau, MD
Published Date: 28 Oct 2026

At CHEST 2026, Jean Bourbeau, MD, said AI may support COPD diagnosis, remote monitoring, and posthospital care, though most tools still need validation.

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Tozorakimab Sustains COPD Exacerbation Benefit to 2 Years: Henrik Watz, MD Henrik Watz, MD, PhD
Published Date: 28 Oct 2026

Henrik Watz, MD, discusses 104-week OBERON, TITANIA, and PROSPERO data on tozorakimab in COPD presented at CHEST 2026.

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Frespaciguat Misses 6MWD End Point in PH-COPD: Gabor Kovacs, MD, PhD Gabor Kovacs, MD, PhD
Published Date: 28 Oct 2026

Gabor Kovacs, MD, PhD, discusses phase 2a INSIGNIA PH-COPD results for inhaled frespaciguat presented at CHEST 2026.

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Ralinepag's Benefit Spans Broad PAH Population, With Jean Elwing, MD
Published Date: 28 Oct 2026

Ralinepag's Benefit Spans Broad PAH Population, With Jean Elwing, MD

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TPIP Tolerable Over 2 Years in PH-ILD, With Colin Church, MBBS, PhD
Published Date: 28 Oct 2026

TPIP Tolerable Over 2 Years in PH-ILD, With Colin Church, MBBS, PhD

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TPIP's Efficacy Holds as PALM-ILD Advances, With Colin Church, MBBS, PhD
Published Date: 28 Oct 2026

TPIP's Efficacy Holds as PALM-ILD Advances, With Colin Church, MBBS, PhD

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Inside The New AHA/ACC Acute Pulmonary Embolism Categories
Published Date: 28 Oct 2026

Inside The New AHA/ACC Acute Pulmonary Embolism Categories

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Calcium Channel Blockers Linked to Lower Blood Pressure Variability Marco Meglio
Published Date: 28 Oct 2026

A target trial emulation pooling ACCORD-BP and SPRINT data found calcium channel blocker regimens reduced blood pressure variability without changing cardiovascular outcomes.

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This Week on NeurologyLive® — October 26, 2026 Isabella Ciccone, MPH
Published Date: 28 Oct 2026

Here's some of what is coming soon to NeurologyLive® this week.

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ATTACK: Should Patients With CKD Start Aspirin for Primary Prevention? Hugh Gallagher, MD
Published Date: 28 Oct 2026

Hugh Gallagher, MBBS, PhD, discusses a 27% lower point estimate for cardiovascular events with aspirin that was not significant.

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RENEW-HD: Portable Hemodialysis Data, With Karin Gerritsen, MD, PhD
Published Date: 28 Oct 2026

RENEW-HD: Portable Hemodialysis Data, With Karin Gerritsen, MD, PhD

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Diabetes Dialogue: MiniMed Vivera Data and Twiist Type 2 Clearance
Published Date: 28 Oct 2026

Diabetes Dialogue: MiniMed Vivera Data and Twiist Type 2 Clearance

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The HCPFive: Top News for Healthcare Providers from the Week of 10/18
Published Date: 28 Oct 2026

The HCPFive: Top News for Healthcare Providers from the Week of 10/18

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Latest News

Many Clinical Paths Are Open to NPs. Here’s Help in Picking

‘A strength of the nurse practitioner profession is its versatility,’ one expert says.

What’s That? Metabolic Disorders Driving Hearing Loss

Often it’s the drugs prescribed to treat obesity and diabetes that may be the cause of hearing issues.

Medicaid Expansion Tied to Reduced Lung Cancer Survival Gaps

After Medicaid expansion, early-stage diagnosis and 3-year survival improve among Americans with lung cancer, primarily those living in nonurban areas.

When GLP-1 Users Choose Meal Replacements, Landmines Linger

Protein bars and shakes may be options, but details matter. Other options are likely better.

Alabama Warns Healthcare Providers Against Use Of Non-FDA-approved Peptides

Alabama's medical regulator on Tuesday warned healthcare providers against prescribing or using so-called research-grade ⁠peptides, saying the substances are not approved by...

Sexual Desire in Menopause May Reflect Psychosocial Factors

Evidence suggests that sexual function may remain stable or improve after menopause, challenging assumptions of decline.

Cholecystectomy Outcomes Improve Despite Patient Complexity

Among Medicare inpatients who undergo minimally invasive cholecystectomy, the rates of overall and serious complications decline over a decade.

IBD Predicts Cognitive Loss — and Vice Versa – in Seniors

Active IBD in older adults is linked to higher odds of cognitive decline over 1 year, and deficits in delayed recall signal an increased risk for active disease.

FDA Marks hopes to act as global regulator to promote gene therapy

FDA Director Peter Marks said Wednesday he hopes to harmonize international regulations to encourage the commercialization of gene and cell therapies to bring more treatments to market for patients with rare diseases.

Pair Echo With Right Heart Catheterization in PH: Anjali Vaidya, MD Anjali Vaidya, MD, FACC, FASE, FACP

Anjali Vaidya, MD, explains why echocardiography should inform right heart catheterization interpretation in pulmonary hypertension at CHEST 2026.

New Trials Favor PE Intervention in Sicker Intermediate-Risk Patients Samantha Pettigrew, MD

Samantha Pettigrew, MD, reviews HI-PEITHO, PRAGUE-26, and PEERLESS and how they shape intervention choices in intermediate-risk PE at CHEST 2026.

CAR-T Agent Zola-cel Shows No New Multiple Sclerosis Disease Activity in Phase 1 Study Louie Pasculli

Updated data from Breakfree-2 study showed that treatment with a single zola-cel infusion achieved NEDA-3 in highly active relapsing multiple sclerosis and led to mostly stable disability in progressive multiple sclerosis.

Houston Forum Highlights Awareness Gaps in NF1 Plexiform Neurofibroma Care Marco Meglio

At a NeurologyLive and Targeted Oncology Clinical Forum in Houston, Kevin J. Bielamowicz, MD, of Arkansas Children’s Hospital, discussed how incidental diagnosis and limited awareness of systemic therapy continue to delay care for patients with NF1-associated plexiform neurofibromas.

Tenecteplase Benefit Before Thrombectomy Varies by Stroke Cause, Study Shows Marco Meglio

A secondary analysis of the BRIDGE-TNK trial found tenecteplase before thrombectomy improved functional outcomes in cardioembolic but not atherosclerotic stroke.

NeurologyLive® Brain Games: October 25, 2026 Louie Pasculli, Marco Meglio

Test your neurology knowledge with NeurologyLive®'s weekly quiz series, featuring questions on a variety of clinical and historical neurology topics. This week's topic is recent advances in gene therapies.

Remibrutinib Lowers Relapse Rate vs Teriflunomide in Relapsing MS Matt Hoffman, Louie Pasculli

Phase 3 data show the oral BTK inhibitor reduced annualized relapse rate by 35.2% and 31.2% vs teriflunomide, with no liver safety signal or Hy's Law cases.

Latest News

Many Clinical Paths Are Open to NPs. Here’s Help in Picking

‘A strength of the nurse practitioner profession is its versatility,’ one expert says.

What’s That? Metabolic Disorders Driving Hearing Loss

Often it’s the drugs prescribed to treat obesity and diabetes that may be the cause of hearing issues.

Medicaid Expansion Tied to Reduced Lung Cancer Survival Gaps

After Medicaid expansion, early-stage diagnosis and 3-year survival improve among Americans with lung cancer, primarily those living in nonurban areas.

When GLP-1 Users Choose Meal Replacements, Landmines Linger

Protein bars and shakes may be options, but details matter. Other options are likely better.

Alabama Warns Healthcare Providers Against Use Of Non-FDA-approved Peptides

Alabama's medical regulator on Tuesday warned healthcare providers against prescribing or using so-called research-grade ⁠peptides, saying the substances are not approved by...

Sexual Desire in Menopause May Reflect Psychosocial Factors

Evidence suggests that sexual function may remain stable or improve after menopause, challenging assumptions of decline.

Cholecystectomy Outcomes Improve Despite Patient Complexity

Among Medicare inpatients who undergo minimally invasive cholecystectomy, the rates of overall and serious complications decline over a decade.

IBD Predicts Cognitive Loss — and Vice Versa – in Seniors

Active IBD in older adults is linked to higher odds of cognitive decline over 1 year, and deficits in delayed recall signal an increased risk for active disease.

FDA Marks hopes to act as global regulator to promote gene therapy

FDA Director Peter Marks said Wednesday he hopes to harmonize international regulations to encourage the commercialization of gene and cell therapies to bring more treatments to market for patients with rare diseases.

Pair Echo With Right Heart Catheterization in PH: Anjali Vaidya, MD Anjali Vaidya, MD, FACC, FASE, FACP

Anjali Vaidya, MD, explains why echocardiography should inform right heart catheterization interpretation in pulmonary hypertension at CHEST 2026.

New Trials Favor PE Intervention in Sicker Intermediate-Risk Patients Samantha Pettigrew, MD

Samantha Pettigrew, MD, reviews HI-PEITHO, PRAGUE-26, and PEERLESS and how they shape intervention choices in intermediate-risk PE at CHEST 2026.

CAR-T Agent Zola-cel Shows No New Multiple Sclerosis Disease Activity in Phase 1 Study Louie Pasculli

Updated data from Breakfree-2 study showed that treatment with a single zola-cel infusion achieved NEDA-3 in highly active relapsing multiple sclerosis and led to mostly stable disability in progressive multiple sclerosis.

Houston Forum Highlights Awareness Gaps in NF1 Plexiform Neurofibroma Care Marco Meglio

At a NeurologyLive and Targeted Oncology Clinical Forum in Houston, Kevin J. Bielamowicz, MD, of Arkansas Children’s Hospital, discussed how incidental diagnosis and limited awareness of systemic therapy continue to delay care for patients with NF1-associated plexiform neurofibromas.

Tenecteplase Benefit Before Thrombectomy Varies by Stroke Cause, Study Shows Marco Meglio

A secondary analysis of the BRIDGE-TNK trial found tenecteplase before thrombectomy improved functional outcomes in cardioembolic but not atherosclerotic stroke.

NeurologyLive® Brain Games: October 25, 2026 Louie Pasculli, Marco Meglio

Test your neurology knowledge with NeurologyLive®'s weekly quiz series, featuring questions on a variety of clinical and historical neurology topics. This week's topic is recent advances in gene therapies.

Remibrutinib Lowers Relapse Rate vs Teriflunomide in Relapsing MS Matt Hoffman, Louie Pasculli

Phase 3 data show the oral BTK inhibitor reduced annualized relapse rate by 35.2% and 31.2% vs teriflunomide, with no liver safety signal or Hy's Law cases.

News All Time

Tegoprubart Improves Quality of Life vs Tacrolimus After Kidney Transplant

Tegoprubart Improves Quality of Life vs Tacrolimus After Kidney Transplant

Sparsentan Lowers Inflammatory, Complement Biomarkers in IgAN

Sparsentan Lowers Inflammatory, Complement Biomarkers in IgAN

More Time in Target Blood Pressure Range Cuts Recurrent Stroke After Intracerebral Hemorrhage Marco Meglio

A pooled analysis of 4 randomized trials found that more time with blood pressure below 130 mmHg after intracerebral hemorrhage reduced recurrent stroke risk.

FDA Accepts Troriluzole NDA Resubmission for Spinocerebellar Ataxia Marco Meglio

The FDA set a first quarter 2027 goal date for troriluzole in spinocerebellar ataxia and plans an advisory committee after a 2025 complete response letter.

What MEnD-AKI Revealed About AI Alerts, With Sandra Kane-Gill, PharmD, MS Sandra Kane-Gill, PharmD, MS

In the MEnD-AKI trial, pharmacists reviewed deep learning predictions of AKI risk across 38 hospital service clusters at 8 hospitals.

AI Alerts Did Not Reduce Kidney Events, With Sandra Kane-Gill, PharmD, MS Sandra Kane-Gill, PharmD, MS

In the MEnD-AKI trial, pharmacists reviewed deep learning predictions of AKI risk across 38 hospital service clusters at 8 hospitals.

Why PAD Goes Undetected in Advanced CKD, With Pranav Garimella, MBBS, MPH Pranav Garimella, MBBS, MPH

Calcified vessels may mask PAD on ankle brachial index testing, and Garimella says nephrologists can help catch it earlier.

Sleeve Gastrectomy Improves Heart, Kidney MRI Markers in Youth-Onset T2D Phoom Narongkiatikhun, MD

Phoom Narongkiatikhun, MD, discusses sleeve gastrectomy reducing LV mass, kidney volume, and albuminuria and boosting medullary FSOC in youth-onset T2D.

Tenapanor Lowers Serum Phosphate Regardless of Binder Use in Dialysis

Tenapanor Lowers Serum Phosphate Regardless of Binder Use in Dialysis

4 Endocrinology Headlines You Missed in August 2026 Chelsie Derman

New approval for tirzepatide, phase 3 wins for avexitide and retatrutide, and a GLP-1 telehealth safety gap in August's biggest endocrinology stories.

Tailoring Pulmonary Rehab to Close the COPD Gap, With Omid Pourshahid, MD Omid Pourshahid, MD

At CHEST 2026, Pourshahid argued for matching patients to center-based, hybrid, or virtual pulmonary rehab based on a structured assessment.

Virtual Pulmonary Rehab and Matched Care, With Omid Pourshahid, MD Omid Pourshahid, MD

Omid Pourshahid, MD, MPH, discusses Medicare coverage for virtual pulmonary rehab and a matched-care pathway for center-based, hybrid, or virtual programs.

Experts Examine Biologic Coverage in Asthma and COPD

Experts Examine Biologic Coverage in Asthma and COPD

Type 2 Phenotyping in Asthma and COPD: Clinical Forum Perspectives

Type 2 Phenotyping in Asthma and COPD: Clinical Forum Perspectives

Ralinepag Cuts PAH Worsening in Low-Risk Patients, With Jean Elwing, MD

Ralinepag Cuts PAH Worsening in Low-Risk Patients, With Jean Elwing, MD

Real-World Data Show Switch to Subcutaneous Ocrelizumab Well Tolerated Marco Meglio

Data from the real-world, CONFIDENCE study found switching from intravenous to subcutaneous ocrelizumab was well tolerated in patients with relapsing and primary progressive MS.

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