GnRH agonists for Endometriosis and Fibroids: Understanding the Science, Interpreting the Evidence, and Applying the Guidelines

Speciality: Obstetrics & Gynaecology


Speaker:

NISHANT MARU | Fertility Specialist

Description:

Today, we’re exploring GnRH agonists and their role in managing endometriosis and fibroids. GnRH agonists work by reducing the production of oestrogen in the body, which can help shrink fibroids and lessen the pain of endometriosis. Evidence shows these medications are effective for symptom relief, but long-term use may lead to side effects such as bone density loss. Current guidelines recommend using GnRH agonists for a limited duration, often alongside add-back therapy to minimise side effects. It’s important for patients and clinicians to weigh the benefits and risks together, ensuring individualised, evidence-based care for the best possible outcomes.

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