GnRH agonists for Endometriosis and Fibroids: Understanding the Science, Interpreting the Evidence, and Applying the Guidelines

Speciality: Obstetrics & Gynaecology


Speaker:

Mr. Dilip Kumar Sahu | Consultant Obstetrician & Gynaecologist

Description:

Today, we’re exploring GnRH agonists and their role in managing endometriosis and fibroids. GnRH agonists work by suppressing the body’s production of oestrogen, which can reduce the growth and symptoms of these conditions. Clinical evidence shows that these medications are effective in relieving pain and reducing the size of fibroids, but long-term use can lead to side effects such as bone loss and menopausal symptoms. Current guidelines recommend using GnRH agonists for short-term relief, often in combination with add-back therapy to minimise side effects. It’s essential to tailor treatment to each individual, balancing benefits and risks. Always discuss options with your healthcare provider for the best approach.

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