GnRH agonists for Endometriosis and Fibroids: Understanding the Science, Interpreting the Evidence, and Applying the Guidelines

Speciality: Obstetrics & Gynaecology


Speaker:

Mr. Dilip Kumar Sahu | Endometriosis Specialist

Description:

Welcome to today’s episode, where we explore GnRH agonists and their use in treating endometriosis and fibroids. GnRH agonists work by reducing the body’s production of oestrogen, which can help relieve symptoms such as pain and heavy bleeding. Clinical evidence shows these medications are effective for short-term management, particularly when other treatments haven’t worked. However, side effects like hot flushes and bone thinning mean they’re usually used for limited periods. Guidelines recommend careful monitoring and sometimes add-back therapy to reduce side effects. Understanding the science and evidence behind GnRH agonists helps patients and clinicians make informed decisions tailored to individual needs.

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