Wide grip pen with magnet designed for people with Parkinson's disease

Published Date: 08 Mar 2023

When grandpa Izzy Mokotoff stopped writing his weekly newsletter in the spring of 2022, he knew he had to find a solution. Parkinson's disease was slowly destroying my grandfather's central nervous system.

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Latest News

Karyopharm's Drug Meets One Of Two Goals in Blood Cancer Trial

Karyopharm Therapeutics said on Tuesday its therapy led to significant reduction in spleen size in a late-stage ⁠study of patients with a rare blood cancer, meeting only one...

Match Day Traditions Are Evolving

Opening the Match Day envelope with other med students is a once-in-a-lifetime event that most students want to celebrate together, but private options are good too.

Getting The Right Signal: Does Program Signaling Work?

Designed to curb application inflation and help mid-tier candidates, signaling is now the ‘make-or-break’ metric for a match. But is it working or creating new problems?

US Proposes Easing Limits on Cancer-causing Gas Used to Clean Medical Devices

The Trump administration is proposing to lift some limits on the use of ethylene oxide, a carcinogenic gas used ⁠for sterilization, saying previous constraints imposed under...

BMA Warns Scottish Medical Schools ‘Beyond Capacity’

Medical student numbers in Scotland have risen 72% since 2015, but teaching capacity and training posts have not kept pace, a BMA report warns.

Federal Loan Caps Will Reduce PA School Applicants

Proposed federal student loan caps will drive students into pricier private loans, or derail their aspirations of becoming PAs, creating professional healthcare shortages.

Todays Updates

Insulin Resistance Detected Early May Guide HS Therapy

Screening for insulin resistance early after the diagnosis of hidradenitis suppurativa shows promise for guiding therapies to improve the disease course.

Dermatomyositis: Targeted Drug Shows Promise vs Placebo

At 52 weeks, the 30-mg daily oral dose of brepocitinib outperformed the 15-mg dose in a study of patients with dermatomyositis resistant to previous treatments.

Melasma: A New Era of Topical Treatment Options Galore

Combination therapies remain key as multiple agents for melasma hit the market.

LAAC an Alternative for NOAC in Lower-Risk AF Patients

CHAMPION-AF finds left atrial appendage closure and anticoagulation therapy for atrial fibrillation about equal but raises doubts about whether the former is a true alternative.

Fibrinolytic Beats Current Standard for Intermediate-Risk PE

For intermediate-risk pulmonary embolism, a low-dose fibrinolysis strategy reduced PE-related events by half with no significant increase in bleeding vs standard therapy.

PCKS9 Inhibitors Seen Driving Down LDL-C in Diabetes

A subgroup analysis of the VESALIUS-CV trial showed evolocumab significantly cut LDL cholesterol and cardiovascular event risk in people with diabetes but no known atherosclerosis.

High Dx Yield Supports Workup for INOCA

Performed with favorable safety, the diagnostic yield for coronary function testing in patients with ischemia but nonobstructive arteries was found to exceed 90%.

Todays Updates

Insulin Resistance Detected Early May Guide HS Therapy

Screening for insulin resistance early after the diagnosis of hidradenitis suppurativa shows promise for guiding therapies to improve the disease course.

Dermatomyositis: Targeted Drug Shows Promise vs Placebo

At 52 weeks, the 30-mg daily oral dose of brepocitinib outperformed the 15-mg dose in a study of patients with dermatomyositis resistant to previous treatments.

Melasma: A New Era of Topical Treatment Options Galore

Combination therapies remain key as multiple agents for melasma hit the market.

LAAC an Alternative for NOAC in Lower-Risk AF Patients

CHAMPION-AF finds left atrial appendage closure and anticoagulation therapy for atrial fibrillation about equal but raises doubts about whether the former is a true alternative.

Fibrinolytic Beats Current Standard for Intermediate-Risk PE

For intermediate-risk pulmonary embolism, a low-dose fibrinolysis strategy reduced PE-related events by half with no significant increase in bleeding vs standard therapy.

PCKS9 Inhibitors Seen Driving Down LDL-C in Diabetes

A subgroup analysis of the VESALIUS-CV trial showed evolocumab significantly cut LDL cholesterol and cardiovascular event risk in people with diabetes but no known atherosclerosis.

High Dx Yield Supports Workup for INOCA

Performed with favorable safety, the diagnostic yield for coronary function testing in patients with ischemia but nonobstructive arteries was found to exceed 90%.

Latest News

Karyopharm Therapeutics said on Tuesday its therapy led to significant reduction in spleen size in a late-stage ⁠study of patients with a rare blood cancer, meeting only one...

Opening the Match Day envelope with other med students is a once-in-a-lifetime event that most students want to celebrate together, but private options are good too.

Designed to curb application inflation and help mid-tier candidates, signaling is now the ‘make-or-break’ metric for a match. But is it working or creating new problems?

The Trump administration is proposing to lift some limits on the use of ethylene oxide, a carcinogenic gas used ⁠for sterilization, saying previous constraints imposed under...

Medical student numbers in Scotland have risen 72% since 2015, but teaching capacity and training posts have not kept pace, a BMA report warns.

Proposed federal student loan caps will drive students into pricier private loans, or derail their aspirations of becoming PAs, creating professional healthcare shortages.

News All Time

Simple test brings clarity and hope for families with inherited neuropathy

A new, inexpensive urine test that measures two sugar alcohols, sorbitol and xylitol, is making it easier, faster, and far less expensive to identify a common inherited nerve disorder called SORD-related neuropathy. The test, ...

Would you put period blood on your face? What science says about 'menstrual masking'

In the ever-evolving world of beauty trends, few have sparked as much debate—and discomfort—as "menstrual masking." This is the practice of applying menstrual blood to the skin, usually the face, as a form of DIY skincare.

Healing the heart after a heart attack with a biodegradable patch

A new patch developed by Texas A&M University researcher Dr. Ke Huang may offer a way to help the heart heal after a heart attack. The patch uses a unique microneedle system to deliver a therapeutic molecule directly to damaged ...

Reaching the unreachable: Endoscopy technique opens route to deep lung tumors

Researchers at the University of Osaka have engineered a novel technique, balloon-assisted bronchoscope delivery (BDBD), to guide endoscopes to small, early-stage lung cancers hidden deep within the periphery of the lungs.

Malaria rapid diagnostic test 'not fit for purpose,' international study claims

An international study published in the Malaria Journal claims that a widely used test for detecting malaria is delivering too many inaccurate false-negative results and is "not fit for purpose."

Ovarian tissue preservation enables future fertility for young woman with cancer

In patients of reproductive age who have cancer, fertility preservation for potential children in the future should be a high priority. A practice article published in the Canadian Medical Association Journal describes the ...

One of the world's oldest blood pressure drugs may also halt aggressive brain tumor growth

A Penn-led team has revealed how hydralazine, one of the world's oldest blood pressure drugs and a mainstay treatment for preeclampsia, works at the molecular level. In doing so, they made a surprising discovery—it can ...

From body fat to bone, experiment offers hope for 'gentle' repair of fractures

Japanese researchers are testing a surprising, minimally invasive way to repair spine fractures.

At some doctors' offices, AI is listening in the exam room

Bracken Babula starts patient visits these days by closing the exam room door and asking if they mind him recording their conversation. He hits a button on his mobile phone, checks that it is recording, and sits back in his ...

Software optimizes brain simulations, enabling them to complete complex cognitive tasks

A new software enables brain simulations which both imitate the processes in the brain in detail and can solve challenging cognitive tasks. The program was developed by a research team at the Cluster of Excellence "Machine ...

GLP-1 and health: Beyond weight loss in the Ozempic era

This week, the White House announced a deal with Eli Lilly and Novo Nordisk to lower the cost of their GLP-1 weight loss drugs, Wegovy and Zepbound. The move could significantly expand access to these treatments for people ...

When life imitates art: Google searches for anxiety drug spike during run of The White Lotus TV show

In season three of the hit television series "The White Lotus," the character Victoria Ratliff takes the prescription anti-anxiety medication lorazepam to help with her social anxiety and inability to sleep. Her casual usage ...

How the brain learns and applies rules: Sequential neuronal dynamics in the prefrontal cortex

Understanding how the brain learns and applies rules is the key to unraveling the neural basis of flexible behavior. A new study from the University of Toyama, Japan, reveals that our ability to follow procedural rules is ...

Computational deep dive reveals hidden cancer drug targets and repurposing opportunities

One person's side effect could be another person's treatment if we expand our perspective on small molecule drug targets, according to a new study published November 5, 2025, in npj Precision Oncology.

Deep learning system could transform skin cancer detection with near-perfect accuracy

Melanoma remains one of the hardest skin cancers to diagnose because it often mimics harmless moles or lesions. While most artificial intelligence (AI) tools rely on dermoscopic images alone, they often overlook crucial patient ...

Digital access improves convenience, but cannot fully replace physical services

A research team from the Urban and Transportation Systems Laboratory, Department of Architecture and Civil Engineering, Toyohashi University of Technology, has developed an innovative evaluation framework that quantitatively ...

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