For elderly, unfit patients, the all-oral AML regimen shows promise.

Published Date: 08 Mar 2024

64 percent of patients who received a new diagnosis responded, compared to 46 percent of patients whose illness was refractory or had relapsed.

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Oral drug combination extends progression-free survival in advanced ER-positive breast cancer

Patients with estrogen-receptor-positive HER-2-negative advanced breast cancer showed significantly improved progression-free survival when treated with an oral combination regimen that includes giredestrant, a novel, next-generation ...

Leukemia cells evade treatment by reshaping their mitochondria, researchers discover

Researchers from Rutgers Health and other institutions have discovered why a powerful leukemia drug eventually fails in most patients—and found a potential way to overcome that resistance.

Dense breasts: What it means and what women can do about screening

About half of women over 40 have dense breasts. The denser the breast tissue, the more difficult it is to spot cancer on a standard mammogram. Having dense breast tissue can make it harder to detect cancer and sometimes leads ...

Chemotherapy combination boosts overall survival in patients with EGFR-mutant non-small cell lung cancer

In recent research, treatment with osimertinib plus a platinum–pemetrexed chemotherapy combination resulted in statistically significant and clinically meaningful improvement in overall survival in patients with newly diagnosed ...

Should the UK introduce targeted prostate cancer screening? The case for and against

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Tumor infiltration of major blood vessels, not metastasis, may be primary cause of cancer death

The ultimate cause of death from cancer may not be metastatic disease, as researchers have long surmised, but an infiltration of tumors into major blood vessels that cause blood clots and multiorgan failure, a one-of-a-kind ...

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mRNA-based COVID vaccines generate improved responses to immunotherapy

Patients with cancer who received mRNA-based COVID vaccines within 100 days of starting immune checkpoint therapy were twice as likely to be alive three years after beginning treatment, according to a new study led by researchers ...

Research finds COVID-19 mRNA vaccine sparks immune response to fight cancer

Patients with advanced lung or skin cancer who received a COVID-19 mRNA vaccine within 100 days of starting immunotherapy drugs lived significantly longer than those who did not get the vaccine, researchers have found.

Todays Updates

mRNA-based COVID vaccines generate improved responses to immunotherapy

Patients with cancer who received mRNA-based COVID vaccines within 100 days of starting immune checkpoint therapy were twice as likely to be alive three years after beginning treatment, according to a new study led by researchers ...

Research finds COVID-19 mRNA vaccine sparks immune response to fight cancer

Patients with advanced lung or skin cancer who received a COVID-19 mRNA vaccine within 100 days of starting immunotherapy drugs lived significantly longer than those who did not get the vaccine, researchers have found.

Latest News

Patients with estrogen-receptor-positive HER-2-negative advanced breast cancer showed significantly improved progression-free survival when treated with an oral combination regimen that includes giredestrant, a novel, next-generation ...

Researchers from Rutgers Health and other institutions have discovered why a powerful leukemia drug eventually fails in most patients—and found a potential way to overcome that resistance.

About half of women over 40 have dense breasts. The denser the breast tissue, the more difficult it is to spot cancer on a standard mammogram. Having dense breast tissue can make it harder to detect cancer and sometimes leads ...

In recent research, treatment with osimertinib plus a platinum–pemetrexed chemotherapy combination resulted in statistically significant and clinically meaningful improvement in overall survival in patients with newly diagnosed ...

Former UK prime minister Rishi Sunak has called for a targeted prostate cancer screening program for men most at high risk of the disease, reviving a national debate on how to save more lives and tackle health inequalities ...

The ultimate cause of death from cancer may not be metastatic disease, as researchers have long surmised, but an infiltration of tumors into major blood vessels that cause blood clots and multiorgan failure, a one-of-a-kind ...

News All Time

Nanoparticle vaccine prevents multiple cancers and stops metastasis in mice

A study led by University of Massachusetts Amherst researchers demonstrates that their nanoparticle-based vaccine can effectively prevent melanoma, pancreatic and triple-negative breast cancer in mice. Not only did up to ...

Nuclear missile workers are contracting cancer: They blame the bases

At a memorial service in 2022, veteran Air Force Capt. Monte Watts bumped into a fellow former Minuteman III nuclear missile operator, who told him that she had non-Hodgkin lymphoma.

A radiotheranostic approach designed to combat aggressive cancers

UCLA scientists, together with a team of international collaborators, have identified a promising new treatment strategy that can detect, kill and reprogram aggressive, treatment-resistant tumors like osteosarcomas and glioblastoma.

Exercise may help breast cancer survivors manage weight

New UBC Okanagan research shows that exercise can do more than improve the strength and cardiovascular endurance of women who have survived breast cancer.

Immune cell homing hydrogel-based platform captures dendritic cells to process mRNA from cancer vaccines

A research team led by Cancer Center at Illinois (CCIL) member Hua Wang has published new research detailing a new mRNA cancer vaccine platform. The study introduces an immune cell homing hydrogel-based platform designed ...

Lesser-known lobular breast cancer on the rise in U.S. women

The American Cancer Society has released a report on occurrence and outcomes in the United States for this subtype of breast cancer. Findings show an estimated 33,600 women will be diagnosed with lobular breast cancer or ...

Study recommends new grading system for invasive squamous cell carcinoma of the lung

Invasive lung squamous cell carcinoma (LUSC) accounts for approximately one-quarter of all lung cancers, but therapeutic options for LUSC remain limited, primarily due to the absence of well-defined, targetable molecular ...

Neural networks and label-free microscopy enable accurate detection of pancreatic tumors

Pancreatic neuroendocrine neoplasms (PNENs) are a rare form of cancer that affects hormone-producing cells in the pancreas. Although uncommon, their incidence has been rising steadily over the past few decades.

Q&A: Breast cancer facts that could save lives

October is Breast Cancer Awareness Month, a time to spotlight a disease that will affect hundreds of thousands of Americans this year. In the U.S., a new case of breast cancer is diagnosed about every two minutes, with more ...

Patients value communication skills from cancer surgeons across six key areas, according to research

Facing a cancer diagnosis can be one of the most stressful times for patients and their loved ones. When seeking a surgeon for treatment, providing emotional support and helping patients manage expectations are among the ...

Drop in credit score after cancer diagnosis linked to increased mortality

Patients with cancer whose credit scores decline after their diagnosis face a significantly higher risk of mortality, providing the first objective data linking financial health to physical survival.

A healthier lifestyle after bowel screening shown to prevent bowel cancer

If you adopt a healthier lifestyle after bowel screening, it can lower your risk of both bowel cancer and other chronic diseases, a new study shows.

Analysis of NRG trial in limited-stage small cell lung cancer suggests QOL benefit with twice- vs. once-daily radiation

Previously, the primary endpoint results of the NRG-LU005 study assessing the addition of the immunotherapy drug atezolizumab to standard of care concurrent chemoradiation for limited-state small cell lung cancer were reported ...

Herpes virus-based vaccine shows promise in targeting tumors without side effects

The Herpes simplex virus is a widespread virus that often causes cold sores, and most people carry it. By removing a virulence gene, i.e. a gene that makes the virus harmful to humans, the herpes virus can be repurposed as ...

Women who miss their first mammogram face higher risk of breast cancer death, study finds

Women who miss their first mammogram run a higher risk of being diagnosed with advanced breast cancer and dying from the disease. This is shown in a new study from Karolinska Institutet published in BMJ.

Zebrafish models offer fast, effective guidance for personalized therapies for kids with high-risk cancer

Molecular profiling has transformed cancer care, but 30% of high-risk pediatric cancers do not have actionable therapeutic targets, limiting personalized treatment options and negatively affecting survival outcomes.

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