FDA review of dupilumab for chronic spontaneous urticaria

Published Date: 13 Mar 2023

The FDA approval request for CSU is based on data from a pair of Phase 3 trials in two different populations.

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When sheriff's deputies intercepted a trailer carrying six horses near the border town of Redford, Texas, they uncovered more than a livestock violation. The animals had...

‘Medicine shines through’ when evidence-based medicine isn’t enough.

In suspected urosepsis, urine culture matched the pathogen found in blood culture in 54.6% of episodes while delivering results faster, potentially enabling earlier targeted antimicrobial therapy.

An educational quality improvement program significantly reduces hospital-onset methicillin-resistant Staphylococcus aureus bacteremia events across all the participating hospital units.

Mental health campaigner Sir Norman Lamb sets out the four questions he thinks the NHS must answer to fix mental healthcare.

A rare immune cell linked to cancer resistance increases in the very old, suggesting the immune system actively adapts to extreme longevity.

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Salmonella Cases Top 500 in Outbreak Linked to Imported Eggs

The UKHSA says the outbreak now spans three genetically distinct Salmonella clusters, but the risk to the public remains low.

Rebel-held Eastern Congo Records New Ebola Case After Declaring Outbreak Over

A new Ebola case has been recorded in an area controlled by ⁠AFC/M23 rebels in eastern Congo, the group said, more than two months after it declared ⁠the outbreak over in...

5 Things Doctors Should Know About Medical AI Regulation

Federal and state regulators are drawing new boundaries around medical AI, from how the tools are vetted to who bears responsibility when they fail.

AI Speeds Up Chest Radiograph Readings but Lowers Accuracy

Commercial AI tools for chest radiography reduce reading time and boost reader confidence but fail to improve diagnostic accuracy.

Second RSV Dose Recommended for Some Kids

The updated recommendations reflect a growing consensus among medical organizations that a second-dose RSV vaccine can provide additional protection.

Sequencing of TAVI Before PCI Found to be Noninferior

Although percutaneous intervention for coronary artery disease is commonly performed before transcatheter aortic valve implantation in those who need both, a trial supports either sequence.

5 Ways to Spot Sepsis Before It’s Too Late

A patient who seems ‘just a little sick’ may be far more ill than they appear. These signs can help clinicians spot sepsis sooner.

Anastomotic Repair Tied to Lower Stricture Recurrence Risk

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Shorter Premedication May Not Raise Contrast Reaction Risk

In patients with iodinated contrast allergy, contrast-enhanced CT imaging performed within 4 hours of intravenous steroid and diphenhydramine premedication is not linked to higher breakthrough reactions.

Skin Deep: Could Clues Reveal Underlying Disease Early?

From liver disease to malignancy, characteristic skin findings can prompt a broader evaluation and help physicians consider systemic conditions during routine examinations.

Novartis MS Pill Beats Older Drug in Trials, Boosts Pipeline Hopes

(Corrects paragraph 12 to say remi is approved to treat only one skin condition, not two)

Teva's Immune Disorder Drug Meets Main Goal in Mid-stage Trial

Israeli drugmaker Teva Pharmaceutical Industries, said on Wednesday its experimental drug helped prevent gluten-related intestinal damage in ⁠adults with celiac disease,...

Maternal HIV Treatment May Aid Child Viral Load Suppression

Children living with HIV whose mothers receive antiretroviral therapy or achieve viral load suppression are more likely to receive antiretroviral therapy themselves.

Lipid-Lowering Drugs Tied to Worse Venom Anaphylaxis

Patients receiving lipid-lowering medications face roughly double the odds of severe anaphylaxis after Hymenoptera stings compared with those not taking these medications.

Controversial Drug Suspended Due to Trial Irregularities

MHRA suspends new use of avacopan after concluding pivotal trial data can no longer be trusted, despite real-world evidence of efficacy.

Exclusive-US Refusals Of Crucial Newborn Vitamin Spike, Raising Risk Of Dangerous Bleeding

The percentage of parents and caregivers in the United States refusing a standard vitamin K shot for infants at birth has accelerated sharply this year, an exclusive data...

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