FDA review of dupilumab for chronic spontaneous urticaria

Published Date: 13 Mar 2023

The FDA approval request for CSU is based on data from a pair of Phase 3 trials in two different populations.

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Limited numeracy affects how patients interpret risk and treatment benefits, highlighting the need for clear, structured numerical communication to support shared decision-making.

Emapalumab Effectively Controls MAS in Patients With Lupus

Patients substantially reduce their average steroid dose and report MAS events for 1 year.

Itch Tracker: Potential Use in Managing Pediatric AD

Use of a nighttime scratch tracker app is linked to reduced scratching activity and treatment response.

Nutritional Deficiencies Can Mimic Rheumatologic Conditions

Individuals with restrictive eating behaviors, developmental disorders, or malabsorption are particularly at risk.

Survey Highlights Caregiver Dietary Concerns in Kids With AD

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Allergy Affects 1 in 4 With Common Variable Immunodeficiency

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Todays Updates

Nodal Response After Chemo Helps Tailor Breast Radiotherapy

Ten-year findings suggest some patients may safely receive less treatment, potentially lowering side effects without raising recurrence risk.

Latest News

Limited numeracy affects how patients interpret risk and treatment benefits, highlighting the need for clear, structured numerical communication to support shared decision-making.

Patients substantially reduce their average steroid dose and report MAS events for 1 year.

Use of a nighttime scratch tracker app is linked to reduced scratching activity and treatment response.

Individuals with restrictive eating behaviors, developmental disorders, or malabsorption are particularly at risk.

The most common concerns include which foods might cause or trigger atopic dermatitis, when to introduce solid foods, and treatment of atopic dermatitis through the gut.

Over one fourth of patients with common variable immunodeficiency have allergic diseases, with immunoglobulin E levels linked to immune dysregulation and severe phenotypes.

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Liver Enzyme Guides Prognosis in CKD Patients on Dialysis

Among patients with CKD, serum total ALP and its liver, bone, and intestinal fractions increase with disease severity, and liver ALP is associated with mortality in those undergoing haemodialysis.

‘I HATE YOU’ and Other Things People Say to Their Doctors

Patient rudeness, in-person or on the portal, is more common than ever, and data now show it’s taking a toll on quality care.

Medical Accuracy of 'The Pitt'

The cast and creators of HBO Max's 'The Pitt' explain how they get the medicine right, and why it matters.

COVID Shots in Pregnancy Protect Infants’ First 6 Months

The research adds important evidence for clinicians counseling pregnant patients.

Barzolvolimab Shows Persistent Benefits for CSU

Patients maintain their improvements off treatment, even after clearance of barzolvolimab, investigators report.

Specialty Care in Crisis in British Columbia

Long wait times for an appointment with a specialist and for treatment after the referral are putting lives at risk, experts say.

Review Finds Benefits of Biotic Therapy for Acne

‘It is theorized that probiotics improve skin barrier hydration through multiple mechanisms, including modulation of the skin microbiome,’ according to the authors.

FDA Withdraws Proposal to Prohibit Minors From Tanning Beds

‘Restricting teens’ access to indoor tanning and informing the public about the dangers of indoor tanning are critical to preventing skin cancer,’ AAD President Susan C. Taylor, MD, said.

Will Healthcare Data Become Easier to Access in Canada?

The Canadian government introduced legislation to make it easier for patients and physicians to access and share electronic medical records and other types of health data.

Pediatric Dermatology Wait Time Nearly 90 Days

Children experience longer wait times to see a pediatric dermatologist than general dermatologists for common skin conditions, a study finds.

Risk Tool Flags Infection Risk After High‑Dose Steroids

A novel scoring system can effectively stratify patients with autoimmune inflammatory rheumatic diseases into high- and low-risk groups for serious infections after high-dose glucocorticoid therapy.

Hidradenitis Suppurativa Linked to Increased Cancer Risk

A meta-analysis shows that hidradenitis suppurativa is associated with a higher risk for multiple cancer subtypes.

Shingles Vaccine Safe, Less Immunogenic With Abatacept in RA

Patients with RA who use abatacept mount little humoral or cell-mediated responses to the recombinant zoster vaccine, with more injection-site reactions but similar RA flare rates compared with placebo.

Normal Ultrasound Does Not Rule Out Term Risk

Despite detecting most severely small foetuses at the scan between 35 and 36 weeks, most stillbirths and serious neonatal complications still arise in foetuses that appear normal on ultrasound.

Measles Cases in South Carolina Rise by One to 997, State Health Department Says

Measles cases in South Carolina surged to 997 on Tuesday, ⁠state health data showed, including one additional infection since Friday.

IgAn Diagnostic and Therapeutic Strategies

Explore how updated KDIGO IgAN guidelines, earlier biopsy driven risk stratification, and new targeted therapies (budesonide, sparsentan, complement/APRIL inhibitors) are reshaping long term outcomes.

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