FDA review of dupilumab for chronic spontaneous urticaria

Published Date: 13 Mar 2023

The FDA approval request for CSU is based on data from a pair of Phase 3 trials in two different populations.

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Childhood AD Not Tied to Cardiovascular Risk in Adulthood

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Use of a nighttime scratch tracker app is linked to reduced scratching activity and treatment response.

Individuals with restrictive eating behaviors, developmental disorders, or malabsorption are particularly at risk.

The most common concerns include which foods might cause or trigger atopic dermatitis, when to introduce solid foods, and treatment of atopic dermatitis through the gut.

Over one fourth of patients with common variable immunodeficiency have allergic diseases, with immunoglobulin E levels linked to immune dysregulation and severe phenotypes.

Atopic dermatitis in childhood is not associated with increased early markers of cardiovascular risk, a study finds.

This practical review explains when to stop ACEI, diuretics, SGLT2 inhibitors, metformin, and NSAIDs during dehydration — how to safely reinstate therapy.

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Medical Accuracy of 'The Pitt'

The cast and creators of HBO Max's 'The Pitt' explain how they get the medicine right, and why it matters.

COVID Shots in Pregnancy Protect Infants’ First 6 Months

The research adds important evidence for clinicians counseling pregnant patients.

Barzolvolimab Shows Persistent Benefits for CSU

Patients maintain their improvements off treatment, even after clearance of barzolvolimab, investigators report.

Specialty Care in Crisis in British Columbia

Long wait times for an appointment with a specialist and for treatment after the referral are putting lives at risk, experts say.

Review Finds Benefits of Biotic Therapy for Acne

‘It is theorized that probiotics improve skin barrier hydration through multiple mechanisms, including modulation of the skin microbiome,’ according to the authors.

FDA Withdraws Proposal to Prohibit Minors From Tanning Beds

‘Restricting teens’ access to indoor tanning and informing the public about the dangers of indoor tanning are critical to preventing skin cancer,’ AAD President Susan C. Taylor, MD, said.

Will Healthcare Data Become Easier to Access in Canada?

The Canadian government introduced legislation to make it easier for patients and physicians to access and share electronic medical records and other types of health data.

Pediatric Dermatology Wait Time Nearly 90 Days

Children experience longer wait times to see a pediatric dermatologist than general dermatologists for common skin conditions, a study finds.

Risk Tool Flags Infection Risk After High‑Dose Steroids

A novel scoring system can effectively stratify patients with autoimmune inflammatory rheumatic diseases into high- and low-risk groups for serious infections after high-dose glucocorticoid therapy.

Hidradenitis Suppurativa Linked to Increased Cancer Risk

A meta-analysis shows that hidradenitis suppurativa is associated with a higher risk for multiple cancer subtypes.

Shingles Vaccine Safe, Less Immunogenic With Abatacept in RA

Patients with RA who use abatacept mount little humoral or cell-mediated responses to the recombinant zoster vaccine, with more injection-site reactions but similar RA flare rates compared with placebo.

Normal Ultrasound Does Not Rule Out Term Risk

Despite detecting most severely small foetuses at the scan between 35 and 36 weeks, most stillbirths and serious neonatal complications still arise in foetuses that appear normal on ultrasound.

IgAn Diagnostic and Therapeutic Strategies

Explore how updated KDIGO IgAN guidelines, earlier biopsy driven risk stratification, and new targeted therapies (budesonide, sparsentan, complement/APRIL inhibitors) are reshaping long term outcomes.

Measles Cases in South Carolina Rise by One to 997, State Health Department Says

Measles cases in South Carolina surged to 997 on Tuesday, ⁠state health data showed, including one additional infection since Friday.

Peanut Introduction Kits Encourage Earlier Peanut Feeding

Peanut kits given in pediatric clinics were linked to a threefold increase in caregivers introducing the legume 2 months later.

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