FDA review of dupilumab for chronic spontaneous urticaria

Published Date: 13 Mar 2023

The FDA approval request for CSU is based on data from a pair of Phase 3 trials in two different populations.

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A rodent-borne virus with a scary name. A mid-ocean cruise ship in quarantine. Several people dead and more falling sick.

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NICE Backs First Immunotherapy for Resectable Gastric Cancer

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Novel IL-17A Inhibitor Shows Efficacy in Axial SpA

Compared with placebo, vunakizumab 120 mg significantly improves signs and symptoms of radiographic axial spondyloarthritis at week 16, with sustained efficacy through week 32.

Combo Therapy Tied to Better Quality of Life in Rhinitis

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Hidradenitis Suppurativa Tied to Higher Cardiovascular Risks

Individuals with HS show higher risks for cardiovascular outcomes, including hypertension, coronary or ischemic heart disease, venous thromboembolism, and myocardial infarction, in a meta-analysis.

Todays Updates

Hidradenitis Suppurativa Tied to Higher Cardiovascular Risks

Individuals with HS show higher risks for cardiovascular outcomes, including hypertension, coronary or ischemic heart disease, venous thromboembolism, and myocardial infarction, in a meta-analysis.

Latest News

A rodent-borne virus with a scary name. A mid-ocean cruise ship in quarantine. Several people dead and more falling sick.

Guidelines advise slow serum sodium correction to avoid osmotic demyelination, but recent data suggest that risk is low, and rapid correction may produce better outcomes.

NICE has recommended durvalumab for NHS use in England as part of perioperative treatment for adults with resectable gastric or gastro-oesophageal junction adenocarcinoma.

Researchers note that microlithiasis and biliary sludge are common causes of presumed idiopathic pancreatitis, which standard ultrasound often fails to detect.

Compared with placebo, vunakizumab 120 mg significantly improves signs and symptoms of radiographic axial spondyloarthritis at week 16, with sustained efficacy through week 32.

In patients with allergic rhinitis, fixed combinations of intranasal antihistamines and corticosteroids are tied to better quality-of-life outcomes than oral or intranasal antihistamines alone.

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TNF Plus IL-23 Inhibition for PsA: Better Than IL-23 Alone?

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Ultraprocessed Food Intake Tied to High Asthma Risk in Kids

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Large language models performed better after full clinical data became available, raising concerns about early triage decision-making.

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CMS Wants Healthier Hospital Food, But Patient Needs Vary

Federal agency wants hospitals to more closely follow new Dietary Guidelines for Americans.

Hantavirus Protocol Breach At Dutch Hospital as Medics Race to Curb Spread

A Dutch hospital has quarantined 12 staff members as a preventive measure after blood and urine from a hantavirus patient were handled without observing strict protocols, as...

Language Models as Emergency Room Decision Support

A Science study finds modern large language models often match or exceed physicians in emergency room diagnostic decisions, especially at initial triage, but real-world trials remain essential.

26-Year-Old Man With Posttransfusion Hyperhemolysis

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Exclusive-Kennedy's Health Officials Explored US Ban Of Some Widely Used Antidepressants, Sources Say

U.S. health department officials last week explored whether they could ban certain drugs in a widely prescribed class of antidepressants as Health Secretary Robert F....

Four Factors Keep ‘At-Risk’ Group Arthritis-Free at 10 Years

People with ‘good’ prognostic factors at baseline are less likely to progress to rheumatoid arthritis at 5 and 10 years after presentation, a cohort study finds.

Reduced Kidney Function Tied to Lower Remission Rates in RA

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Early Trauma May Shape Outcomes in Childhood-Onset Lupus

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