FDA review of dupilumab for chronic spontaneous urticaria

Published Date: 13 Mar 2023

The FDA approval request for CSU is based on data from a pair of Phase 3 trials in two different populations.

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Saturated Fat Tied to Worse Survival After Prostate Cancer

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The percentage of parents and caregivers in the United States refusing a standard vitamin K shot for infants at birth has accelerated sharply this year, an exclusive data...

Experts highlight the positive impact biologic treatments have had on the care of patients with atopic dermatitis, with even more promising agents in development.

A digital decision-support tool aligned with allergic rhinitis guidelines may aid in identifying opportunities to adjust allergic rhinitis treatment among primary care patients.

A 5-day-old girl born at 23 weeks’ gestation was evaluated in the neonatal intensive care unit for a skin lesion on the back. What’s the diagnosis?

Experts say clinicians should reassure pregnant patients that inhaled corticosteroids are safe and emphasize the risks of stopping treatment.

A federal lawsuit challenges the 2025-2030 Dietary Guidelines, alleging that conflicts of interest and a secretive process violated federal law.

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Rapid ART Boosts Early HIV Care Retention

Starting antiretroviral therapy immediately after HIV diagnosis appears to keep patients engaged in care during critical early months, though the advantage fades by 1 year.

Deep Dive: NSAIDs: Selectivity Isn't Destiny

Dr Steven Nissen's PRECISION trial upended assumptions about which NSAID is "safest." A look at 7 agents through a cardiovascular, GI, and renal lens.

Serum IL-6 Levels and 9 CV and Mortality Outcomes

An analysis of the association between blood IL-6 measures from 14 multiethnic, prospective cohorts with follow-up data on any of 9 prespecified outcomes.

Forced Birth Control in Greenland Violated Women's Rights but Didn't Constitute Genocide, Experts Find

A campaign of forced contraception in Greenland that ran primarily in the 1960s and 1970s violated women's human rights but did not meet the legal definition of genocide,...

Early Antivirals May Cut Child Flu Hospitalization Risk

Antiviral treatment started within 48 hours of symptom onset is linked to a reduced risk for hospitalization among pediatric patients with influenza.

AstraZeneca-Amgen Asthma Drug Succeeds in Late-stage Oesophagus Disease Trial

AstraZeneca said on Thursday its asthma drug Tezspire met the main goals of a late-stage trial in patients with a chronic inflammatory disorder ⁠of the oesophagus, offering...

Food Allergy or Intolerance? Key Clues for Clinicians

Food reactions are not always allergies. A Paris expert outlined how timing, symptoms, and testing help clinicians separate intolerance from true immune-mediated disease.

US FDA Approves Gilead's Once-daily Combination Pill for HIV Treatment

(This Aug 27 story has been republished, with no changes to text.)

Does PIH Coexist With Skin Inflammation? Experts Weigh In

‘Visible hyperpigmentation may mask persistent erythema and should not be assumed to indicate resolved inflammation,’ according to the authors of a recently published commentary.

Success After a Century Of Failures: Inside Moderna and Merck's Cancer Vaccine Breakthrough

Stephane Bancel, CEO of Moderna, was at a Lebanese restaurant celebrating a friend’s birthday late on August 13 when he got the call.

Atopic Dermatitis Linked to Lower Height in Children

Children with moderate-to-severe atopic dermatitis show lower heights and higher BMI, a study finds.

Allergy Diagnoses Fell During COVID Pandemic

The incidence of most allergy diseases shows a sharp and sustained decline across the COVID pandemic years, a trend that persists beyond what reduced healthcare visits alone can explain.

Key Changes in Pediatric Resuscitation in 2025

The ERC’s 2025 pediatric resuscitation update simplifies airway management, drug dosing, and post-ROSC care to help teams act faster in emergencies.

Mild TBI Mortality Reaches 13.6% at 12 Months

Death rate in patients with mild TBI is 13.6% at 12 months; patients with Glasgow Coma Scale scores of 13-14 have a higher death risk than those with score 15, a study shows.

Daptomycin, Linezolid Use Safe From Resistance Rise

Increased daptomycin and linezolid use is not linked to clinically significant increases in resistance in Gram-positive bacteria over 8 years, study suggests.

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In patients undergoing hemodialysis, GLP-1 RA use is associated with lower levels of inflammatory markers and lower requirements for anemia medications.

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