Discovery of estrogen receptor 'switches' may aid breast cancer treatment

Published Date: 15 Jan 2025

Researchers at Case Western Reserve University School of Medicine have discovered how specific protein regions contribute to breast cancer. Their study, published recently in Nature, focuses on what is known as the estrogen ...

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Cancer is a challenging enough diagnosis, but many patients are dealt a second blow, even as they heal: "chemo brain."

Study opens up possibility of bespoke prostate cancer treatment

A new study led by University of Manchester scientists has identified genetic variants that make some patients more sensitive to radiation in specific parts of the rectum than others. The knowledge could reduce the risk of ...

Top 10 questions about breast cancer answered

Breast cancer receives much attention during October's awareness month. Although sightings of pink ribbons and breast cancer-related information increase during the month, it's crucial to keep screenings and clinical breast ...

Nanoparticle vaccine prevents multiple cancers and stops metastasis in mice

A study led by University of Massachusetts Amherst researchers demonstrates that their nanoparticle-based vaccine can effectively prevent melanoma, pancreatic and triple-negative breast cancer in mice. Not only did up to ...

Nuclear missile workers are contracting cancer: They blame the bases

At a memorial service in 2022, veteran Air Force Capt. Monte Watts bumped into a fellow former Minuteman III nuclear missile operator, who told him that she had non-Hodgkin lymphoma.

Immune cell homing hydrogel-based platform captures dendritic cells to process mRNA from cancer vaccines

A research team led by Cancer Center at Illinois (CCIL) member Hua Wang has published new research detailing a new mRNA cancer vaccine platform. The study introduces an immune cell homing hydrogel-based platform designed ...

Todays Updates

Prior authorizations draining time, energy from many cancer patients

Cancer patients aren't just battling a deadly disease—part of their time and energy can also be spent fighting the system intended to cure them, a new study says. The findings are published in the journal JCO Oncology Practice.

Breast awareness: What to look for in your self-exam

October is Breast Cancer Awareness Month, and cancer awareness starts with general breast awareness. Dr. Julie Nangia, medical director of breast oncology at the Dan L Duncan Comprehensive Cancer Center, recommends monthly ...

New imaging solution could help improve survival for patients with recurring prostate cancer

A multicenter study led by London Health Sciences Centre Research Institute (LHSCRI), Lawson Research Institute of St. Joseph's Health Care London (Lawson), and University Health Network (UHN) has found a novel imaging solution, ...

Loneliness and social isolation linked to heightened risk of death in those with cancer

Loneliness and social isolation are linked to a heightened risk of death from cancer as well as from all causes among those with the disease, finds a pooled data analysis of the available research published online in the ...

Todays Updates

Prior authorizations draining time, energy from many cancer patients

Cancer patients aren't just battling a deadly disease—part of their time and energy can also be spent fighting the system intended to cure them, a new study says. The findings are published in the journal JCO Oncology Practice.

Breast awareness: What to look for in your self-exam

October is Breast Cancer Awareness Month, and cancer awareness starts with general breast awareness. Dr. Julie Nangia, medical director of breast oncology at the Dan L Duncan Comprehensive Cancer Center, recommends monthly ...

New imaging solution could help improve survival for patients with recurring prostate cancer

A multicenter study led by London Health Sciences Centre Research Institute (LHSCRI), Lawson Research Institute of St. Joseph's Health Care London (Lawson), and University Health Network (UHN) has found a novel imaging solution, ...

Loneliness and social isolation linked to heightened risk of death in those with cancer

Loneliness and social isolation are linked to a heightened risk of death from cancer as well as from all causes among those with the disease, finds a pooled data analysis of the available research published online in the ...

Latest News

Cancer is a challenging enough diagnosis, but many patients are dealt a second blow, even as they heal: "chemo brain."

A new study led by University of Manchester scientists has identified genetic variants that make some patients more sensitive to radiation in specific parts of the rectum than others. The knowledge could reduce the risk of ...

Breast cancer receives much attention during October's awareness month. Although sightings of pink ribbons and breast cancer-related information increase during the month, it's crucial to keep screenings and clinical breast ...

A study led by University of Massachusetts Amherst researchers demonstrates that their nanoparticle-based vaccine can effectively prevent melanoma, pancreatic and triple-negative breast cancer in mice. Not only did up to ...

At a memorial service in 2022, veteran Air Force Capt. Monte Watts bumped into a fellow former Minuteman III nuclear missile operator, who told him that she had non-Hodgkin lymphoma.

A research team led by Cancer Center at Illinois (CCIL) member Hua Wang has published new research detailing a new mRNA cancer vaccine platform. The study introduces an immune cell homing hydrogel-based platform designed ...

News All Time

Analysis of NRG trial in limited-stage small cell lung cancer suggests QOL benefit with twice- vs. once-daily radiation

Previously, the primary endpoint results of the NRG-LU005 study assessing the addition of the immunotherapy drug atezolizumab to standard of care concurrent chemoradiation for limited-state small cell lung cancer were reported ...

Zebrafish models offer fast, effective guidance for personalized therapies for kids with high-risk cancer

Molecular profiling has transformed cancer care, but 30% of high-risk pediatric cancers do not have actionable therapeutic targets, limiting personalized treatment options and negatively affecting survival outcomes.

Women who miss their first mammogram face higher risk of breast cancer death, study finds

Women who miss their first mammogram run a higher risk of being diagnosed with advanced breast cancer and dying from the disease. This is shown in a new study from Karolinska Institutet published in BMJ.

Cancer deaths expected to rise to over 18 million in 2050, nearly 75% more than in 2024

There has been a rapid increase in the global number of cancer cases and deaths between 1990 and 2023, despite advances in cancer treatment and efforts to tackle cancer risk factors over that same time period.

Distribution of fat could influence cancer risk, study suggests

How fat is distributed in people's bodies could make a difference to their risk of certain cancers, according to new research led by the University of Bristol. The study is published in JNCI: Journal of the National Cancer ...

WHO releases new R&D landscape analyses highlighting gaps and inequities in cancer research

WHO has released a new landscape analysis that exposes critical gaps in global research and development (R&D) efforts related to cancer. The report reveals that despite rapid advancements in clinical research, investment ...

New PET tracer enables same-day imaging of triple-negative breast and urothelial cancers

A promising new PET tracer can visualize a protein that is commonly overexpressed in triple-negative breast and urothelial bladder cancers within four hours, according to research published in the Journal of Nuclear Medicine. ...

Severe obesity associated with reduced prevalence of recommended cancer screenings

In a recent cross-sectional study, researchers from Pennington Biomedical Research Center found that severe obesity is associated with a lower rate of cancer screenings. In their paper published in JAMA Network Open, "Obesity ...

Health researchers discuss Medicaid cancer screening trends, best practices

New Jersey has the 10th-highest rate of cancer incidence in the United States. It is the second leading cause of death in New Jersey, and thousands of residents die from preventable cancers each year.

Obesity-associated cancers may be on the rise in Puerto Rico

The incidence of obesity-associated cancers in Puerto Rico rose significantly between 2000 and 2022, according to research presented at the 18th AACR Conference on the Science of Cancer Health Disparities, held September ...

Glioblastoma cells can 'unstick' from their neighbors to become more deadly

A new study, led by researchers at Sylvester Comprehensive Cancer Center, part of the University of Miami Miller School of Medicine, captured details of glioblastoma that had never before been seen and revealed a surprise ...

Study finds 10% of pediatric blood cancers may stem from medical imaging radiation

A study led by UC San Francisco and UC Davis has concluded that radiation from medical imaging is associated with a higher risk of blood cancers in children.

Scientists identify dual protein targets to weaken pancreatic cancer defenses

Indiana University School of Medicine scientists have identified a new way to weaken pancreatic cancer's defenses by targeting two key proteins that help the deadly disease resist treatment. The study, recently published ...

Algorithm that predicts pancreatic cancer metastasis could help avoid unnecessary surgeries

Pancreatic cancer remains one of the biggest challenges in the field of oncology. Numbers of cases are increasing, and the latest personalized therapies and immunotherapy are not yet yielding results. Much of the effort is ...

Basal stem-like cells identified as origin of small cell lung cancer in lab models

A new study reveals that small cell lung cancer (SCLC) likely begins in basal stem-like cells rather than in neuroendocrine cells, marking a major shift in the understanding of this aggressive disease that is often associated ...

Targeted radiation therapy shows near-complete response in rare sarcoma patients

A novel targeted radiation approach for a rare form of malignant tumor—the solitary fibrous tumor (SFT)—has shown significant success, achieving a near-complete response in three patients. The therapy significantly reduced ...

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