Team finds broken 'brake' on cancer mutation machine.

Published Date: 09 Aug 2023

According to a group led by UT Southwestern Medical, loss of the SYNCRIP gene in prostate cancer tumors unleashes cellular machinery that leads to random mutations throughout the genome that increase resistance to targeted therapies.

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A single, targeted high dose of radiation delivered before other treatments could completely eradicate tumors in most women with early-stage, operable hormone-positive breast cancer, according to a study led by UT Southwestern ...

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