Team finds broken 'brake' on cancer mutation machine.

Published Date: 09 Aug 2023

According to a group led by UT Southwestern Medical, loss of the SYNCRIP gene in prostate cancer tumors unleashes cellular machinery that leads to random mutations throughout the genome that increase resistance to targeted therapies.

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Todays Updates

Combination vaccines: Can fewer shots mean better outcomes?

Combination vaccines: Can fewer shots mean better outcomes?

FDA approves roflumilast cream 0.05% for atopic dermatitis for children aged 2 to 5 years

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Facing a cancer diagnosis can be one of the most stressful times for patients and their loved ones. When seeking a surgeon for treatment, providing emotional support and helping patients manage expectations are among the ...

Patients with cancer whose credit scores decline after their diagnosis face a significantly higher risk of mortality, providing the first objective data linking financial health to physical survival.

If you adopt a healthier lifestyle after bowel screening, it can lower your risk of both bowel cancer and other chronic diseases, a new study shows.

The Herpes simplex virus is a widespread virus that often causes cold sores, and most people carry it. By removing a virulence gene, i.e. a gene that makes the virus harmful to humans, the herpes virus can be repurposed as ...

Previously, the primary endpoint results of the NRG-LU005 study assessing the addition of the immunotherapy drug atezolizumab to standard of care concurrent chemoradiation for limited-state small cell lung cancer were reported ...

There has been a rapid increase in the global number of cancer cases and deaths between 1990 and 2023, despite advances in cancer treatment and efforts to tackle cancer risk factors over that same time period.

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Glioblastoma cells can 'unstick' from their neighbors to become more deadly

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Remote monitoring can improve recovery from cancer surgery

A new study co-authored by Tracy Crane, Ph.D., RDN, co-leader of the Cancer Control Program at Sylvester Comprehensive Cancer Center, part of the University of Miami Miller School of Medicine, shows that remote perioperative ...

Basal stem-like cells identified as origin of small cell lung cancer in lab models

A new study reveals that small cell lung cancer (SCLC) likely begins in basal stem-like cells rather than in neuroendocrine cells, marking a major shift in the understanding of this aggressive disease that is often associated ...

Algorithm that predicts pancreatic cancer metastasis could help avoid unnecessary surgeries

Pancreatic cancer remains one of the biggest challenges in the field of oncology. Numbers of cases are increasing, and the latest personalized therapies and immunotherapy are not yet yielding results. Much of the effort is ...

Targeted radiation therapy shows near-complete response in rare sarcoma patients

A novel targeted radiation approach for a rare form of malignant tumor—the solitary fibrous tumor (SFT)—has shown significant success, achieving a near-complete response in three patients. The therapy significantly reduced ...

As pesticides and wildfires rise, kids with cancer need resources

A growing body of research ties environmental pollutants to worse health and shorter life spans for childhood cancer survivors. Yet medical providers lack sufficient resources to address these risks with patients, a recent ...

Two-part prodrug system activates immune attack only in tumor's unique environment

Scientists have developed a smarter way to activate the immune system against cancer, potentially making treatments safer and more precise.

Study finds primary-care doctors often overlook prostate cancer risk in Black men

Although Black men die of prostate cancer at twice the rate of the rest of U.S. males, this fact often is not known or considered during appointments with their primary-care clinicians to discuss a common screening test.

Research exposes far-reaching toll of financial hardship on patients with cancer

When someone mentions the word "toxicity" in relation to cancer treatment, they're usually referring to the negative physical side effects and complications that can result from therapies like radiation and chemotherapy. ...

Retired Olympic athletes at greater risk of skin cancer and osteoarthritis, research reveals

Researchers from Keele University have revealed that retired Olympic athletes are more likely to develop skin cancer and osteoarthritis than the general population.

Rural colon cancer patients face higher risks, but minimally invasive surgery could narrow gap

Surgical patients in rural areas who are undergoing colectomy for cancer could benefit greatly from the expanded use of minimally invasive surgery, according to new research findings published in the Journal of the American ...

How to keep your prostate healthy and lower your risk of developing serious problems

For something so small, the prostate can cause big problems. This gland, which is roughly the size of a walnut, is an essential part of a man's urinary and reproductive systems.

Millions of men could benefit from faster scan to diagnose prostate cancer

A quicker, cheaper MRI scan was just as accurate at diagnosing prostate cancer as the current 30–40 minute scan and should be rolled out to make MRI scans more accessible to men who need one, according to clinical trial ...

UK study evaluates effectiveness of cancer diagnosis pathway for patients with non-specific symptoms

A major UK study has provided the most comprehensive analysis to date of a cancer diagnosis pathway for patients presenting with non-specific symptoms (NSS), such as unexplained weight loss or fatigue. These symptoms can ...

Surgery after EGFR TKI shows promise in prolonging progression-free survival in metastatic NSCLC

A randomized Phase II trial from National Taiwan University Hospital reports early evidence that resecting the primary thoracic tumor following EGFR tyrosine kinase inhibitor (TKI) therapy may prolong disease control in patients ...

How cancer misinformation exploits the way we think

When TV personality Danielle Lloyd was diagnosed with melanoma earlier this year, she faced not only the anxiety of cancer treatment but also a disturbing reality: influencers spreading dangerous misinformation about sun ...

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