November 2023, Medical Bulletin 04/.

Published Date: 06 Nov 2023

The following are the top stories in medical news today: Swiss study finds nationwide evidence linking frequent mobile phone use to lower-quality sperm in young men.

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Optimizing Care Transitions and Referral Decision-Making Across the HNSCC Continuum

Optimizing Care Transitions and Referral Decision-Making Across the HNSCC Continuum

Here's Why Hematuria in a Young Patient Should Always Be Investigated

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Liver Failure or Liver Mets?

Diagnosis complicated by absence of radiologic evidence of hepatic lesions

BRAF Inhibition in Pediatric Ameloblastoma of the Jaw

Targeted therapy in 3 boys allowed for conservative surgery to restore jaw to predisease state

Diagnosis of Mass Confined to the Kidney: Is It RCC or TCC?

Ureteroscopy and histopathology should be considered as routine preoperative assessments

Transforming Perioperative MIBC Care in Community Practice: Navigating Emerging Data, Guideline Changes, and Adverse Event Management Protocols

Transforming Perioperative MIBC Care in Community Practice: Navigating Emerging Data, Guideline Changes, and Adverse Event Management Protocols

Todays Updates

Benign or Malignant? No Way to Tell Radiologically

Case shows importance of accurate preop diagnosis

FDA Advisors Recommend Galleri Multicancer Blood Test

Some panelists had reservations about the test's true benefit, however

FDA Approves New Option for Previously Treated Bile Duct Cancer

— Trial of lirafugratinib showed responses in almost half of patients, with good durability

Todays Updates

Benign or Malignant? No Way to Tell Radiologically

Case shows importance of accurate preop diagnosis

FDA Advisors Recommend Galleri Multicancer Blood Test

Some panelists had reservations about the test's true benefit, however

FDA Approves New Option for Previously Treated Bile Duct Cancer

— Trial of lirafugratinib showed responses in almost half of patients, with good durability

Latest News

Optimizing Care Transitions and Referral Decision-Making Across the HNSCC Continuum

Terminology also makes a difference

Diagnosis complicated by absence of radiologic evidence of hepatic lesions

Targeted therapy in 3 boys allowed for conservative surgery to restore jaw to predisease state

Ureteroscopy and histopathology should be considered as routine preoperative assessments

Transforming Perioperative MIBC Care in Community Practice: Navigating Emerging Data, Guideline Changes, and Adverse Event Management Protocols

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Significant Survival Boost With Novel ADCs in Relapsed Small-Cell Lung Cancer

Death risk cut by 54% with B7-H3-targeting tambotatug pelitecan and risvutatug rezetecan

Nurse Accused of Exorcism; Death After 8 Hours of Plastic Surgery; Top Cancer Months

Health news and commentary gathered by MedPage Today staff

Brain MRI Surveillance Alone Helps Preserve Cognition in Small Cell Lung Cancer

Omitting prophylactic cranial irradiation led to improved cognitive failure-free survival

Cancer Drug Shortages Continue With No Immediate Path Toward Relief

All responding NCCN members reported shortages, priorities identified but solutions still needed

ROS1-Targeting Lung Cancer Drug Yields 90% Response Rate

Early efficacy among the highest seen in lung cancer, expert says

Drug Combo's Response Rates Top 90% in Small Cell Lung Cancer Trial

Bispecific antibody and ADC together impress in early study

Novel Drug Cuts Risk for Death by 44% in Squamous Lung Cancer Trial

If approved, immunotherapy gotistobart could offer a chemo-free option in second-line setting

Unprecedented PFS in HER2-Mutant Lung Cancer, but With a Touch of Controversy

Practice-changing median of 14.3 months with T-DXd, but caution over early unfavorable OS trend

Woman Develops Tiny Blood Spots on Her Body After COVID Shot

Case highlights need for quick diagnosis and management of rare disorder

Two Survival Wins in NSCLC With Bispecific Seeking Worldwide Status

Ivonescimab topped pembrolizumab alone or paired with chemotherapy in separate trials

Patient's Colonoscopy Refusal Highlights Value of CRC Screening

Man with a first-degree relative with CRC initially only agreed to stool-based testing

RFK Jr. Eyes Wireless, RF Radiation; Cancer by the Month; AI for Cancer Symptoms

News, features, and commentary about cancer-related issues

FDA Staff Find No Major Concerns With Galleri Multicancer Early Detection Test

— Comments were noncommittal in agency document released ahead of advisors' meeting

Definium's LSD-based Anxiety, Depression Drug Scores Another Trial Win

Definium Therapeutics said on Monday its LSD-based treatment reduced symptoms of generalized anxiety disorder ⁠in a second successful late-stage study for the...

Liberalized Cannabis Policies May Increase Substance Use

In a global review, legalization was associated with increased cannabis use and related emergency department visits, with potential decreases in the use of alcohol and tobacco.

UK Lawmakers Reject Bid to Legalise Assisted Dying

British lawmakers rejected on Friday a proposal to legalise assisted dying for terminally ill people, dealing a major setback to campaigners and bringing the latest effort...

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November 2023, Medical Bulletin 04/.

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