Gene therapies for BCG-unresponsive bladder cancer have high response rates.

Published Date: 10 May 2024

Complete responses were seen in 75% of patients, and these were generally found to be long-lasting.

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Tumor infiltration of major blood vessels, not metastasis, may be primary cause of cancer death

The ultimate cause of death from cancer may not be metastatic disease, as researchers have long surmised, but an infiltration of tumors into major blood vessels that cause blood clots and multiorgan failure, a one-of-a-kind ...

High-speed whole-body SPECT tracks tumor evolution to optimize prostate cancer treatment

A new fast and convenient approach to scintigraphy-based monitoring allows physicians to efficiently and reliably assess prostate cancer progression or regression during treatment. With this strong prognostic information, ...

After cancer: Study explores caring-healing modalities for survivors

As cancer survivorship rises, many people living with or beyond cancer face lasting physical and emotional challenges—particularly anxiety and depression, which affect about 30% of this population. Emotional distress is ...

Study identifies new approach to protect the brain during radiation therapy

While tremendous relief comes from successfully battling cancer, survivors can also experience cognitive impairments caused by the disease and its treatment. Up to 70% of survivors experience trouble with memory and concentration, ...

Loneliness and social isolation linked to heightened risk of death in those with cancer

Loneliness and social isolation are linked to a heightened risk of death from cancer as well as from all causes among those with the disease, finds a pooled data analysis of the available research published online in the ...

New imaging solution could help improve survival for patients with recurring prostate cancer

A multicenter study led by London Health Sciences Centre Research Institute (LHSCRI), Lawson Research Institute of St. Joseph's Health Care London (Lawson), and University Health Network (UHN) has found a novel imaging solution, ...

Todays Updates

Should the UK introduce targeted prostate cancer screening? The case for and against

Former UK prime minister Rishi Sunak has called for a targeted prostate cancer screening program for men most at high risk of the disease, reviving a national debate on how to save more lives and tackle health inequalities ...

Chemotherapy combination boosts overall survival in patients with EGFR-mutant non-small cell lung cancer

In recent research, treatment with osimertinib plus a platinum–pemetrexed chemotherapy combination resulted in statistically significant and clinically meaningful improvement in overall survival in patients with newly diagnosed ...

Dense breasts: What it means and what women can do about screening

About half of women over 40 have dense breasts. The denser the breast tissue, the more difficult it is to spot cancer on a standard mammogram. Having dense breast tissue can make it harder to detect cancer and sometimes leads ...

Leukemia cells evade treatment by reshaping their mitochondria, researchers discover

Researchers from Rutgers Health and other institutions have discovered why a powerful leukemia drug eventually fails in most patients—and found a potential way to overcome that resistance.

Todays Updates

Should the UK introduce targeted prostate cancer screening? The case for and against

Former UK prime minister Rishi Sunak has called for a targeted prostate cancer screening program for men most at high risk of the disease, reviving a national debate on how to save more lives and tackle health inequalities ...

Chemotherapy combination boosts overall survival in patients with EGFR-mutant non-small cell lung cancer

In recent research, treatment with osimertinib plus a platinum–pemetrexed chemotherapy combination resulted in statistically significant and clinically meaningful improvement in overall survival in patients with newly diagnosed ...

Dense breasts: What it means and what women can do about screening

About half of women over 40 have dense breasts. The denser the breast tissue, the more difficult it is to spot cancer on a standard mammogram. Having dense breast tissue can make it harder to detect cancer and sometimes leads ...

Leukemia cells evade treatment by reshaping their mitochondria, researchers discover

Researchers from Rutgers Health and other institutions have discovered why a powerful leukemia drug eventually fails in most patients—and found a potential way to overcome that resistance.

Latest News

The ultimate cause of death from cancer may not be metastatic disease, as researchers have long surmised, but an infiltration of tumors into major blood vessels that cause blood clots and multiorgan failure, a one-of-a-kind ...

A new fast and convenient approach to scintigraphy-based monitoring allows physicians to efficiently and reliably assess prostate cancer progression or regression during treatment. With this strong prognostic information, ...

As cancer survivorship rises, many people living with or beyond cancer face lasting physical and emotional challenges—particularly anxiety and depression, which affect about 30% of this population. Emotional distress is ...

While tremendous relief comes from successfully battling cancer, survivors can also experience cognitive impairments caused by the disease and its treatment. Up to 70% of survivors experience trouble with memory and concentration, ...

Loneliness and social isolation are linked to a heightened risk of death from cancer as well as from all causes among those with the disease, finds a pooled data analysis of the available research published online in the ...

A multicenter study led by London Health Sciences Centre Research Institute (LHSCRI), Lawson Research Institute of St. Joseph's Health Care London (Lawson), and University Health Network (UHN) has found a novel imaging solution, ...

News All Time

Neural networks and label-free microscopy enable accurate detection of pancreatic tumors

Pancreatic neuroendocrine neoplasms (PNENs) are a rare form of cancer that affects hormone-producing cells in the pancreas. Although uncommon, their incidence has been rising steadily over the past few decades.

Q&A: Breast cancer facts that could save lives

October is Breast Cancer Awareness Month, a time to spotlight a disease that will affect hundreds of thousands of Americans this year. In the U.S., a new case of breast cancer is diagnosed about every two minutes, with more ...

Study recommends new grading system for invasive squamous cell carcinoma of the lung

Invasive lung squamous cell carcinoma (LUSC) accounts for approximately one-quarter of all lung cancers, but therapeutic options for LUSC remain limited, primarily due to the absence of well-defined, targetable molecular ...

Lesser-known lobular breast cancer on the rise in U.S. women

The American Cancer Society has released a report on occurrence and outcomes in the United States for this subtype of breast cancer. Findings show an estimated 33,600 women will be diagnosed with lobular breast cancer or ...

Patients value communication skills from cancer surgeons across six key areas, according to research

Facing a cancer diagnosis can be one of the most stressful times for patients and their loved ones. When seeking a surgeon for treatment, providing emotional support and helping patients manage expectations are among the ...

Drop in credit score after cancer diagnosis linked to increased mortality

Patients with cancer whose credit scores decline after their diagnosis face a significantly higher risk of mortality, providing the first objective data linking financial health to physical survival.

A healthier lifestyle after bowel screening shown to prevent bowel cancer

If you adopt a healthier lifestyle after bowel screening, it can lower your risk of both bowel cancer and other chronic diseases, a new study shows.

Herpes virus-based vaccine shows promise in targeting tumors without side effects

The Herpes simplex virus is a widespread virus that often causes cold sores, and most people carry it. By removing a virulence gene, i.e. a gene that makes the virus harmful to humans, the herpes virus can be repurposed as ...

Analysis of NRG trial in limited-stage small cell lung cancer suggests QOL benefit with twice- vs. once-daily radiation

Previously, the primary endpoint results of the NRG-LU005 study assessing the addition of the immunotherapy drug atezolizumab to standard of care concurrent chemoradiation for limited-state small cell lung cancer were reported ...

Zebrafish models offer fast, effective guidance for personalized therapies for kids with high-risk cancer

Molecular profiling has transformed cancer care, but 30% of high-risk pediatric cancers do not have actionable therapeutic targets, limiting personalized treatment options and negatively affecting survival outcomes.

Women who miss their first mammogram face higher risk of breast cancer death, study finds

Women who miss their first mammogram run a higher risk of being diagnosed with advanced breast cancer and dying from the disease. This is shown in a new study from Karolinska Institutet published in BMJ.

Cancer deaths expected to rise to over 18 million in 2050, nearly 75% more than in 2024

There has been a rapid increase in the global number of cancer cases and deaths between 1990 and 2023, despite advances in cancer treatment and efforts to tackle cancer risk factors over that same time period.

New PET tracer enables same-day imaging of triple-negative breast and urothelial cancers

A promising new PET tracer can visualize a protein that is commonly overexpressed in triple-negative breast and urothelial bladder cancers within four hours, according to research published in the Journal of Nuclear Medicine. ...

Severe obesity associated with reduced prevalence of recommended cancer screenings

In a recent cross-sectional study, researchers from Pennington Biomedical Research Center found that severe obesity is associated with a lower rate of cancer screenings. In their paper published in JAMA Network Open, "Obesity ...

WHO releases new R&D landscape analyses highlighting gaps and inequities in cancer research

WHO has released a new landscape analysis that exposes critical gaps in global research and development (R&D) efforts related to cancer. The report reveals that despite rapid advancements in clinical research, investment ...

Distribution of fat could influence cancer risk, study suggests

How fat is distributed in people's bodies could make a difference to their risk of certain cancers, according to new research led by the University of Bristol. The study is published in JNCI: Journal of the National Cancer ...

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