De-Intensified Therapy Misses Mark in HPV-Positive Oropharyngeal Cancer

Published Date: 04 Oct 2024

With 98% PFS at 2 years, standard RT plus cisplatin sets a higher bar for de-escalation

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Psychotropics Linked to Increased BMI, CVD Risk

Psychotropics are associated with increased BMI, and users with a high BMI genetic risk score and an unhealthy lifestyle have triple the risk for CVD, new research shows.

Adjuvant Radiation Boosts High-Risk Bladder Cancer Control

For patients with high-risk muscle-invasive bladder cancer, adjuvant radiotherapy improves disease control without increasing the risk of serious side effects.

Blood Test Flags Mantle Cell Lymphoma Relapse Before PET-CT

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WHO Warns Loosely Regulated Nicotine Pouches Risk Youth Addiction

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Novel ADC Improves Survival in Metastatic TNBC

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Proton Therapy Fails to Beat IMRT in Prostate Cancer

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Fuzuloparib Add-On Improves Metastatic Prostate Cancer rPFS

Researchers track progression-free survival after adding a PARP inhibitor to a standard regimen for metastatic castration-resistant prostate cancer.

Todays Updates

Isatuximab Boosts MRD Negativity in Multiple Myeloma

Researchers compare two different treatment regimens in 446 transplant-ineligible patients with newly diagnosed multiple myeloma in a global phase 3 trial.

Novel ADC Improves Survival in Metastatic TNBC

Izalontamab brengitecan extends overall survival among patients with metastatic TNBC, but it’s unclear how the investigational therapy might fit into an evolving treatment landscape.

Proton Therapy Fails to Beat IMRT in Prostate Cancer

For men with localized prostate cancer, proton therapy looks no better than IMRT when it comes to 3-year biochemical progression or GI toxicity.

Fuzuloparib Add-On Improves Metastatic Prostate Cancer rPFS

Researchers track progression-free survival after adding a PARP inhibitor to a standard regimen for metastatic castration-resistant prostate cancer.

Latest News

Researchers increasingly suggest that biological diversity within schizophrenia may limit efforts to identify a single defining biomarker.

Psychotropics are associated with increased BMI, and users with a high BMI genetic risk score and an unhealthy lifestyle have triple the risk for CVD, new research shows.

For patients with high-risk muscle-invasive bladder cancer, adjuvant radiotherapy improves disease control without increasing the risk of serious side effects.

Results pinpoint who has the worst prognosis and might benefit from different therapies.

Neuromodulation, mind-body therapy, and other nonpharmacologic interventions are linked to improved psychiatric symptoms in people with SUD, a meta-analysis shows.

The World Health Organization on Friday urged governments to do more to control the sale of nicotine pouches, warning ⁠that the highly addictive products were being...

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Next-Generation KRAS G12C Inhibitor Shows 'Robust' Efficacy in Advanced Lung Cancer

Responses observed in patients with and without previous exposure to other KRAS G12C inhibitors

CAR-T Trial Raises Prospect of Preventing Myeloma in High-Risk Group

All 20 smoldering myeloma patients had deep responses after one-time infusion

More Positive Survival Data in Lung Cancer With Perioperative Therapy

High rate of tumor DNA clearance with chemoimmunotherapy portends improved EFS, possibly OS

Study Linking Fruits, Veggies to Lung Cancer Raises Eyebrows

Association by way of pesticide exposure proposed, but outside experts not so sure

SCOTUS Grapples With Multibillion-Dollar Lawsuits Over Roundup Cancer Claims

Several justices seemed sympathetic to Monsanto's argument that it can't be sued under state law

Rectal Cancer 'Crisis'; Smells Like Cancer; Flushing Away Clues to Colon Cancer

News, features, and commentary about cancer-related issues

Lung Cancer Screening Rates in Eligible Adults Remain Low, Uneven

However, rates were improved from previous survey results

FDA Says First 'Real-Time' Clinical Trial Is Underway

Two sponsors are on board, with a larger pilot program planned later this year

Novel Mimetic Bispecific Antibody Superior to Standard Care in Hemophilia A

Mim8 prophylaxis significantly reduced bleeding events in patients with or without inhibitors

High Rate of Surgical Success in Complex NSCLC With Neoadjuvant Chemoimmunotherapy

Three-fourths of patients had cancer-free mediastinal lymph nodes, clear surgical margins in 93%

Pooled Cord Blood Transplants Achieve Near-Perfect Results in Early Trial

Disease-free survival of 96% with no severe GVHD in acute leukemia, other blood cancers

FDA Panel Endorses Capivasertib Use in Prostate Cancer

Agency staff expressed uncertainty over whether PFS benefit was "clinically meaningful"

Paging Dr. AI; Myth Busting in Cancer; Oncologists Shine in Malpractice Survey

News, features, and commentary about cancer-related issues

J. Craig Venter, Who Won the Race to Sequence the Human Genome, Dies at 79

His death followed a hospitalization for cancer treatment side effects

I Was Told I Had 6 Months to Live. That Was 20 Years Ago.

Here's what two brain surgeries taught me about public health and care access

Woman Loses 6-Year Battle With Mouth Tumor

Rare ameloblastoma rapidly recurs and metastasizes despite numerous radical excisions

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