Exercise Intensity Over Volume Linked to Lower Disease Risks

Published Date: 13 Apr 2026

Higher intensity of physical activity, regardless of total volume, is linked to significantly lower risks for many cardiovascular and other chronic diseases and death.

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Latest News

Insurers Fail to Get Specific on Prior Authorization Reforms

An industry trade group says prior authorization requirements have declined by 11% after last year’s pledge, but the numbers are fuzzy.

MHRA Approves Olezarsen for Rare Lipid Disorder

The MHRA has approved olezarsen for familial chylomicronaemia syndrome, a rare disorder linked to life-threatening pancreatitis.

Long COVID May Increase Your Heart Disease Risk

Individuals with long COVID face a substantially higher risk of developing cardiovascular disease — particularly cardiac arrhythmias and coronary artery disease — than those without long COVID.

Tirzepatide Bests Semaglutide in 12-Month Real-World Study

Tirzepatide is associated with a greater mean percent body weight reduction than semaglutide in adults with obesity or overweight and one or more related complications.

BP Lower Than Target in Many With Coronary Heart Disease

Over one third of patients with coronary heart disease have blood pressure below targets recommended by European guidelines and have elevated risks for heart and kidney diseases.

Lower LDL-C Target May Improve CV Outcomes

A study finds direct evidence to support guideline changes that promote lower targets for low-density lipoprotein cholesterol.

Todays Updates

A Nutritional Experiment: State-by-State Changes in SNAP

Dr Wilkoff wonders what the effects will be of 12 states proposing changes to restricted foods under SNAP.

Trump Officials Consider Ophthalmologist Hemmati for Top Vaccine Post, Reports Say

The Trump administration is considering appointing Houman Hemmati, an ⁠ophthalmologist and a frequent Fox News guest, to lead the FDA's Center ⁠for Biologics Evaluation and...

Residency Training May Formalize Digital Competencies

Medical residents report limited structured training in AI and digital health despite increasing clinical relevance.

Reusable Catheters Just as Safe as Disposables

Reusable catheter strategies may be as safe as single-use devices for preventing UTIs, but questions remain about their practical use.

A Simple Test Could Predict a Patient’s Final 24 Hours

New research suggests the loss of the corneal reflex — a classic marker of brain death — could help clinicians make more specific assessments during the final days and hours of life.

Multidose Ibuprofen Regimen Eases IUD Insertion Pain

Taking three doses of ibuprofen before the insertion of an intrauterine device reduces pain during the procedure compared with a placebo.

AI Chatbots Vary Widely on Fake Medical References

A study of nine AI chatbots found hallucination rates from 0% to 34%, with Grok 3 performing the worst and Perplexity Research being most reliable.

Todays Updates

A Nutritional Experiment: State-by-State Changes in SNAP

Dr Wilkoff wonders what the effects will be of 12 states proposing changes to restricted foods under SNAP.

Trump Officials Consider Ophthalmologist Hemmati for Top Vaccine Post, Reports Say

The Trump administration is considering appointing Houman Hemmati, an ⁠ophthalmologist and a frequent Fox News guest, to lead the FDA's Center ⁠for Biologics Evaluation and...

Residency Training May Formalize Digital Competencies

Medical residents report limited structured training in AI and digital health despite increasing clinical relevance.

Reusable Catheters Just as Safe as Disposables

Reusable catheter strategies may be as safe as single-use devices for preventing UTIs, but questions remain about their practical use.

A Simple Test Could Predict a Patient’s Final 24 Hours

New research suggests the loss of the corneal reflex — a classic marker of brain death — could help clinicians make more specific assessments during the final days and hours of life.

Multidose Ibuprofen Regimen Eases IUD Insertion Pain

Taking three doses of ibuprofen before the insertion of an intrauterine device reduces pain during the procedure compared with a placebo.

AI Chatbots Vary Widely on Fake Medical References

A study of nine AI chatbots found hallucination rates from 0% to 34%, with Grok 3 performing the worst and Perplexity Research being most reliable.

Latest News

An industry trade group says prior authorization requirements have declined by 11% after last year’s pledge, but the numbers are fuzzy.

The MHRA has approved olezarsen for familial chylomicronaemia syndrome, a rare disorder linked to life-threatening pancreatitis.

Individuals with long COVID face a substantially higher risk of developing cardiovascular disease — particularly cardiac arrhythmias and coronary artery disease — than those without long COVID.

Tirzepatide is associated with a greater mean percent body weight reduction than semaglutide in adults with obesity or overweight and one or more related complications.

Over one third of patients with coronary heart disease have blood pressure below targets recommended by European guidelines and have elevated risks for heart and kidney diseases.

A study finds direct evidence to support guideline changes that promote lower targets for low-density lipoprotein cholesterol.

News All Time

Veterans Often Miss Out on Quadruple Therapy for HFrEF

Most US veterans who have new heart failure with reduced ejection fraction do not receive all four classes of guideline-directed medical therapy, and many die before starting full therapy, a study finds.

PVR Reduced in Adults With HFpEF, Pulmonary Hypertension

In a phase 2 trial, treatment with sotatercept shows reduced pulmonary vascular resistance and heart outcomes in patients with combined postcapillary and precapillary pulmonary hypertension and HFpEF.

Should Your Patient Be on Statins? Maybe the Eyes Can Tell

A trial of an AI algorithm that uses retina images to evaluate the risk for atherosclerotic cardiovascular disease demonstrates a high level of accuracy.

Europe’s DNR Divide: Why CPR Discussions Are So Difficult

How do you speak with a deteriorating, in-hospital patient about resuscitation decisions? Physician confidence and legal frameworks vary, with direct impacts on patients.

Liraglutide Lessens Sleep Apnea in COPD With Obesity

Liraglutide reduced obstructive sleep apnea severity and improved quality of life in patients with overweight or obesity and COPD in a randomized trial.

Fluid Monitoring Device Can Improve HFpEF Outcomes

By early detection of fluid in the lungs, a device allows early therapy adjustments to reduce all-cause mortality in patients with heart failure with preserved ejection fraction.

Can Vitamin D Promote a Healthier Gut in IBD?

Vitamin D supplementation is linked to less disease activity and inflammation in inflammatory bowel disease and may restore healthy interactions between the immune system and the gut.

Inside the Quest to Predict Disease Before Symptoms Strike

From smartwatches to DNA fragments, scientists are building a ‘dashboard’ for human health, but a high-profile trial shows how difficult it is to prove the tech can save lives.

Australia Bans Use of Genetic Testing Data by Life Insurers

Australia has banned life insurance companies from using genetic testing information to deny or restrict policies.

Two Oral GLP-1s Increase Options for Patient Care

Eli Lilly and Novo Nordisk are in heated competition over orforglipron versus oral semaglutide, respectively, while injectables remain the more potent obesity treatment options.

Impella Comes Up Short in High-Risk PCI: CHIP-BCIS3

High-risk patients with left ventricular dysfunction fare as well, or better, without the support of a microaxial flow pump during complex PCI procedures than those provided with a microaxial flow pump.

Shingles Vaccine Lowers Cardiovascular Risk

Patients with atherosclerotic cardiovascular disease who had received herpes zoster vaccination saw reductions in major adverse cardiac events.

Younger Age Offers No Protection From HFrEF Deaths

Patients with heart failure with reduced ejection fraction, especially those aged 40-49 years, have higher 5-year mortality than peers from the general population.

Active Breath Control Cuts Radiation Dose to Heart

Active breath control significantly reduced radiation dose to the heart and a major artery during treatment for left-sided breast cancer, new data show.

Hormonal Contraception and IIH Risk: New Data

A systematic review and meta-analysis sheds light on the debated association between hormonal contraception and risk for idiopathic intracranial hypertension.

Concerns Continue Over Proposed New Obesity Definitions

The Endocrine Society has concerns of possible delays in care and other problematic areas of The Lancet Commission’s proposed new obesity framework; a Commission author cites ‘conceptual confusions.’

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