Dual-action mRNA vaccine takes aim at aggressive skin cancer

Published Date: 04 Nov 2025

Yale researchers have developed a new vaccine that does double duty against a rare and aggressive skin cancer by targeting the protein essential to tumor cell growth and by adding a key signal to boost the immune system response. ...

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GLP-1 drugs linked to dramatically lower death rates in colon cancer patients

A new University of California San Diego study offers compelling evidence that glucagon-like peptide-1 (GLP-1) receptor agonists—the class of drugs behind Ozempic, Wegovy and Mounjaro, for example—may do more than regulate ...

Best foot forward—chemo care should include podiatry, say researchers

Irreversible nerve damage to the lower limbs is a common side effect of chemotherapy, yet up to 50% of patients are missing out on vital foot care that could significantly ease their symptoms, according to new research from ...

New imaging probe helps track prostate cancer and possibly treat it before resistance develops

Researchers at Wayne State University and the Barbara Ann Karmanos Cancer Institute have developed a chemical imaging probe that resists the breakdown of certain compounds in the body, giving doctors a more dependable way ...

Depression risk higher among long-term breast cancer survivors than women without breast cancer history

Long-term breast cancer survivors have a higher risk for developing depression, particularly if they have insomnia, according to a study published online Oct. 10 in SLEEPJ.

New study elucidates obesity's role in fueling breast cancer progression

Obesity and cancer are two major health challenges of our time, yet the link between them remains only partially understood. New research now highlights a molecular chain of events in estrogen receptor-positive breast cancer, ...

Todays Updates

Better treatments buoy multiple-myeloma patients, bound by research cuts and racial disparities

For more than a year, Diane Hunter, now 72, had been experiencing vague symptoms—pain in her spine and hips, nausea, exhaustion, thirst, and frequent urination. Her primary care physician had ruled out diabetes before finally ...

Newly identified T-cell subtype may explain treatment-resistant childhood leukemia

A new type of cancer cell that "warrants urgent investigation" has been discovered in childhood leukemia and could impact clinical care. Research into new or repurposed treatments that target this new cell type could give ...

Nasal therapeutic HPV vaccine could prevent cervical cancer

Cervical cancer, which affects the reproductive tract, is one of the most common cancers in women worldwide. It is primarily caused by human papillomavirus (HPV), a viral infection that spreads through sexual contact.

Todays Updates

Better treatments buoy multiple-myeloma patients, bound by research cuts and racial disparities

For more than a year, Diane Hunter, now 72, had been experiencing vague symptoms—pain in her spine and hips, nausea, exhaustion, thirst, and frequent urination. Her primary care physician had ruled out diabetes before finally ...

Newly identified T-cell subtype may explain treatment-resistant childhood leukemia

A new type of cancer cell that "warrants urgent investigation" has been discovered in childhood leukemia and could impact clinical care. Research into new or repurposed treatments that target this new cell type could give ...

Nasal therapeutic HPV vaccine could prevent cervical cancer

Cervical cancer, which affects the reproductive tract, is one of the most common cancers in women worldwide. It is primarily caused by human papillomavirus (HPV), a viral infection that spreads through sexual contact.

Latest News

Lung cancer remains the leading cause of cancer death in the U.S., responsible for about 1 in 4, but major advances in screening, surgery and personalized treatment are helping more patients live longer.

A new University of California San Diego study offers compelling evidence that glucagon-like peptide-1 (GLP-1) receptor agonists—the class of drugs behind Ozempic, Wegovy and Mounjaro, for example—may do more than regulate ...

Irreversible nerve damage to the lower limbs is a common side effect of chemotherapy, yet up to 50% of patients are missing out on vital foot care that could significantly ease their symptoms, according to new research from ...

Researchers at Wayne State University and the Barbara Ann Karmanos Cancer Institute have developed a chemical imaging probe that resists the breakdown of certain compounds in the body, giving doctors a more dependable way ...

Long-term breast cancer survivors have a higher risk for developing depression, particularly if they have insomnia, according to a study published online Oct. 10 in SLEEPJ.

Obesity and cancer are two major health challenges of our time, yet the link between them remains only partially understood. New research now highlights a molecular chain of events in estrogen receptor-positive breast cancer, ...

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Indoor hydroponic gardening can improve mental health and quality of life for cancer patients

Indoor hydroponic gardening—a method of growing plants using nutrient-rich water instead of soil—could help cancer patients develop better mental health, eat a healthier diet and enjoy a better overall quality of life.

Clinical trial sees dramatic results using radiation to treat breast cancer

Almost immediately after Theresa Greco was diagnosed with breast cancer in March, doctors asked her whether she wanted to participate in a clinical trial. The trial would do high-powered radiation targeted at her tumor prior ...

FDA approves Blenrep for relapsed or refractory multiple myeloma

The U.S. Food and Drug Administration approved Blenrep (belantamab mafodotin-blmf) in combination with bortezomib and dexamethasone for the treatment of adult patients with relapsed or refractory multiple myeloma.

Molecular profiling of renal medullary carcinoma identifies TROP2 as a promising therapeutic target

Researchers at The University of Texas MD Anderson Cancer Center, in collaboration with BostonGene, conducted the largest and most comprehensive molecular analysis of renal medullary carcinoma (RMC), a rare and aggressive ...

Radiation therapy for patients with breast cancer

Radiation therapy is a common component of breast cancer treatment for patients. The high-powered beams of intense energy kill cancer cells and reduce the risk of the cancer recurring.

Discovery of breast cancer treatment resistance mechanism could lead to new hope for some

Mayo Clinic researchers have discovered a key reason why certain breast cancers might not respond to an important new class of therapeutics called antibody drug conjugates (ADCs). These treatments pair an antibody that targets ...

AI tool identifies women at high risk of interval breast cancer

In a study of more than 100,000 screening mammograms, researchers demonstrated the potential of an AI tool to help identify women at higher risk of developing interval breast cancer, which is breast cancer that is diagnosed ...

Study finds higher breast cancer rates in areas with more air pollution

Women living in parts of the United States with lower air quality, especially neighborhoods with heavy emissions from motor vehicles, are more likely to develop breast cancer, according to a multiyear analysis involving more ...

'Sleep ALL night' program helps children with leukemia sleep better during treatment

Disrupted sleep is a common, often overlooked problem for pediatric patients being treated for acute lymphoblastic leukemia (ALL). To address this issue, researchers at Dana-Farber/Boston Children's Cancer and Blood Disorders ...

COVID-19 mRNA vaccines could unlock the next revolution in cancer treatment

The COVID-19 mRNA-based vaccines that saved 2.5 million lives globally during the pandemic could help spark the immune system to fight cancer. This is the surprising takeaway of a new study that we and our colleagues published ...

Toward rapid and comprehensive genetic diagnosis of pediatric cancer through adaptive sequencing

What if a single test could simultaneously contribute to the diagnosis, characterization, and treatment guidance of childhood cancer—while helping avoid toxic or potentially unnecessary treatments?

Medicaid expansion tied to smaller declines in early-stage cancer detection

During the COVID-19 pandemic, Medicaid expansion was associated with smaller declines in early-stage cancer detection, according to a study published online Oct. 21 in the Journal of the National Cancer Institute.

Many patients learn they could have cancer in the emergency department

Abdominal and chest pain. Injuries. Breathing difficulty. Infections. Mental health emergencies. Those are some of the most common reasons why people go to the local emergency department.

An understudied type of breast cancer poses a lurking threat

University of Colorado Cancer Center member Matthew Sikora, Ph.D., is a national leader in research into an understudied subtype of breast cancer that's on the rise in American women, is often more difficult to detect than ...

How a new light-based cancer treatment could destroy tumors without harming healthy cells—using LEDs

Cancer treatment has come a long way, but many of today's therapies still come with steep costs: not just financial, but physical and emotional too. Chemotherapy and radiotherapy remain vital tools, yet they often damage ...

Report provides global picture of wide inequalities in care for women's cancers

One in five women with breast or cervical cancer in low- and middle-income countries (LMICs) are diagnosed at an early stage, compared with more than one in three in high-income countries (HICs), new research suggests. For ...

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