Atorvastatin cuts anthracycline heart failure

Published Date: 08 Mar 2023

Atorvastatin 40 mg daily for 12 months reduces cardiovascular events in lymphoma patients treated with anthracyclines.

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Exercise Intensity Over Volume Linked to Lower Disease Risks

Higher intensity of physical activity, regardless of total volume, is linked to significantly lower risks for many cardiovascular and other chronic diseases and death.

Genetic Risk Tied to Postpartum BP Risk, BMI Matters More

First-time mothers with high genetic risk for systolic blood pressure have a higher likelihood of postpartum hypertension, but BMI and hypertensive pregnancy disorders are stronger risk factors.

Apixaban May Cut Stroke Risk but Raise Bleeding in Dialysis

Observational data suggest apixaban leads to fewer thromboembolic events but higher bleeding risk, highlighting the need for individualized decision-making in dialysis patients.

AI Model Can Help Cut Hospitalizations in Dialysis Patients

AI-driven interventions reduce the odds of hospitalization within 7 days by 8% in patients with end-stage kidney disease receiving hemodialysis, according to a recent study.

The Case for Muscle Power Over Strength

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Wall Thickness Heterogeneity Improves Cardiomyopathy Detection

Heterogeneity in the thickness of the heart wall, represented by wall thickness standard deviation, can improve the early detection of hypertrophic cardiomyopathy and mutation carriers, a study shows.

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Older adults with chronic disease who have less education, lower income, and no active jobs tend to experience symptoms of depression.

Infection Burden High With Myeloma T-Cell Therapies

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HER2 ADC Shows Promise in Recurrent Endometrial Cancer

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Low Income, Education Tied to Depression in Older Adults

Older adults with chronic disease who have less education, lower income, and no active jobs tend to experience symptoms of depression.

Infection Burden High With Myeloma T-Cell Therapies

A retrospective study suggests a high burden of prolonged, mostly low-grade infections in patients with multiple myeloma who receive T-cell-engaging therapies.

Weight-Based and Fixed-Dose Pembrolizumab Compared in NSCLC

A national cohort study compares the safety and efficacy of weight-based and fixed-dose pembrolizumab regimens in patients with advanced non-small cell lung cancer.

HER2 ADC Shows Promise in Recurrent Endometrial Cancer

Trastuzumab pamirtecan, a HER2-targeted antibody-drug conjugate, achieved ‘exceptional’ antitumor responses in patients with recurrent endometrial cancer, especially those with HER2 IHC 3+ tumors.

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Higher intensity of physical activity, regardless of total volume, is linked to significantly lower risks for many cardiovascular and other chronic diseases and death.

First-time mothers with high genetic risk for systolic blood pressure have a higher likelihood of postpartum hypertension, but BMI and hypertensive pregnancy disorders are stronger risk factors.

Observational data suggest apixaban leads to fewer thromboembolic events but higher bleeding risk, highlighting the need for individualized decision-making in dialysis patients.

AI-driven interventions reduce the odds of hospitalization within 7 days by 8% in patients with end-stage kidney disease receiving hemodialysis, according to a recent study.

The ability to move a weight with force may be a better predictor of mortality risk than how much weight you can move overall. A beneficial tweak for exercise Rx?

Heterogeneity in the thickness of the heart wall, represented by wall thickness standard deviation, can improve the early detection of hypertrophic cardiomyopathy and mutation carriers, a study shows.

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Australia Bans Use of Genetic Testing Data by Life Insurers

Australia has banned life insurance companies from using genetic testing information to deny or restrict policies.

Impella Comes Up Short in High-Risk PCI: CHIP-BCIS3

High-risk patients with left ventricular dysfunction fare as well, or better, without the support of a microaxial flow pump during complex PCI procedures than those provided with a microaxial flow pump.

Two Oral GLP-1s Increase Options for Patient Care

Eli Lilly and Novo Nordisk are in heated competition over orforglipron versus oral semaglutide, respectively, while injectables remain the more potent obesity treatment options.

Shingles Vaccine Lowers Cardiovascular Risk

Patients with atherosclerotic cardiovascular disease who had received herpes zoster vaccination saw reductions in major adverse cardiac events.

Younger Age Offers No Protection From HFrEF Deaths

Patients with heart failure with reduced ejection fraction, especially those aged 40-49 years, have higher 5-year mortality than peers from the general population.

Active Breath Control Cuts Radiation Dose to Heart

Active breath control significantly reduced radiation dose to the heart and a major artery during treatment for left-sided breast cancer, new data show.

Hormonal Contraception and IIH Risk: New Data

A systematic review and meta-analysis sheds light on the debated association between hormonal contraception and risk for idiopathic intracranial hypertension.

Concerns Continue Over Proposed New Obesity Definitions

The Endocrine Society has concerns of possible delays in care and other problematic areas of The Lancet Commission’s proposed new obesity framework; a Commission author cites ‘conceptual confusions.’

SGLT2i Show Cardiorenal, Liver Benefits in Cirrhosis

In patients with type 2 diabetes and cirrhosis, SGLT2 inhibitors show increased efficacy over DPP-4 inhibitors in kidney, cardiac, and liver outcomes.

12 Common Hypertension Pitfalls and How to Fix Them

A review identifies 12 common hypertension errors, highlighting missed diagnostic steps and treatment gaps that may affect long-term cardiovascular outcomes.

Stroke Support System Linked to Fewer Vascular Events

An AI-assisted clinical decision-support system is associated with reduced incidence of vascular events in patients with acute ischemic stroke, a new study shows.

Transcatheter ViV Safe for Failed Bioprostheses

A valve-in-valve procedure for dysfunctional bioprosthetic mitral valves had lower 1-year risk for death and stroke than redo surgery, according to a clinical trial.

Incidental Liver Lesions Common in Patients With CHD on cMRI

Nearly 10% of patients with congenital heart disease have incidental liver lesions detected during cardiac MRI, the majority of which being previously unknown to clinicians.

All-RISE, FAST III: Novel FFR Noninferior to Standard

Two trials showed novel angiography-based physiology assessments were comparable to pressure wire-based approaches for guiding percutaneous coronary intervention.

Sirolimus-Coated Balloon Reduces PAD Amputation Risk

Angioplasty with sirolimus-coated balloons, as compared with uncoated balloons, reduced limb amputation and other adverse events in the SirPAD trial.

Wireless Monitoring Saves Time, May Save Lives

Continuous wireless monitoring reduced in-hospital complications and mortality in an Italian pilot trial and significantly eased nursing workload.

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