Gene Therapy Injections for Knee OA: Where Are We At?

Published Date: 10 Mar 2026

Developers of gene therapies to treat knee osteoarthritis are taking the familiar intra-articular route to deliver proteins and molecules directly to the site of the disease.

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Latest News

A French gynecologist recounts 11 years as Greenland’s lone hospital doctor, where polar nights, isolation, and Inuit hospitality shaped her extraordinary life.

Two groups studied the same cancer mutations in the blood. They agreed on many aspects, including the mechanism at work. But their answers were radically different.

Oral antihistamines appear to be effective in reducing nasal symptoms and improving quality of life compared with placebo in children with allergic rhinitis, a network meta-analysis finds.

The evolution in the types of immunosuppressive therapies used in children and the frequency with which they are prescribed has increased the importance of pretreatment screening for infection risk.

The NHS is rolling out blood matched for red and white cells to kidney transplant patients, potentially averting 100 rejections a year.

Hyponatraemia during the first 72 hours of life is linked to later neurodevelopmental disorders or death in infants with perinatal asphyxia.

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Gram-Negative Bacteria Lead Pediatric Cancer BSIs

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Does CKD Severity Predict Adverse ICU Outcomes?

Among patients in the ICU, the presence and severity of chronic kidney disease are tied to a higher risk for mortality; among those who receive maintenance dialysis, the risk is comparatively lower.

Argenx Drug Vyvgart Meets Goal in Autoimmune Myositis Study

Belgian-Dutch immunology company argenx said on Monday its autoimmune drug Vyvgart met the primary endpoint in a late-stage study in autoimmune myositis, ⁠potentially...

Medical Therapy Reduces Nasal Discharge in CRS

Medical therapy significantly reduces nasal discharge symptoms in chronic rhinosinusitis, with benefits observed in both patients with nasal polyps and those without.

Antioxidants in Vitiligo: Experts Support Select Ingredients

Experts say some antioxidants can improve vitiligo with or without phototherapy, but ingredients backed by evidence remain limited.

Cannabis Use May Increase Fall Risk in Adults With HIV

Among adults living with HIV, cannabis use is associated with an increased risk for falls — but the link weakens after accounting for other substance use and medications.

VNS for RA a Year After Approval: Where Do Things Stand?

A year after approval of the first VNS device for rheumatoid arthritis, many patients are interested and providers in eight states are able to offer the device, but insurers are hesitating.

SLE Linked to Increased Risk for Venous Thromboembolism

Systemic lupus erythematosus is associated with an increased risk for venous thromboembolism, with the highest risk occurring in the first year after diagnosis.

Dermatologists Highlight Cutaneous Signs of Hantavirus

“Hantavirus dermatology is fundamentally about pattern recognition rather than recognition of a specific rash,” one dermatologist points out.

Aug 14 2026 This Week in Cardiology

Listener feedback, the ZEUS trial fails, a fascinating statin trial, more on GLP-1 drugs, and radiation safety in the EP lab are the topics John Mandrola, MD, discusses in this week’s podcast.

RSV Maternal Vaccine Halves Baby Intensive Care Admissions

UKHSA data show a 50% drop in newborn ICU admissions since the RSV maternal vaccine programme took full effect, though officials say low uptake still leaves many babies exposed.

New Evidence Links Atopic Dermatitis to Herpes Zoster

A study of more than 13 million people in the UK finds an association between atopic dermatitis and herpes zoster, including after adjusting for comorbidities, treatments, and other factors.

Antiphospholipid Antibodies Linked to Pregnancy Risks in SLE

Certain antiphospholipid antibody profiles are associated with increased odds of adverse pregnancy outcomes in women with systemic lupus erythematosus.

Metabolic, Autoimmune Links Seen in Sclerosing Mesenteritis

Patients with symptomatic sclerosing mesenteritis often present with abdominal pain and have concurrent autoimmune, malignant, or metabolic disorders.

How Immigration Raids Emptied a Local Pediatric Clinic

Fear of immigration operations keeps vulnerable families away from the doctor, driving a sharp rise in missed appointments and leaving critical childhood care on hold.

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