Maternal type 1 diabetes causes heart defects.

Published Date: 02 Mar 2023

A review of more than 600,000 Finnish births from 2006 to 2016 found that mothers with type 1 diabetes had more than four times as many children born with heart defects.

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Trial data behind the decision showed durable tumour shrinkage and improved pain outcomes with mirdametinib, now recommended by NICE for children from age 2.

Gestational diabetes is linked to an increased risk for type 2 diabetes and other cardiometabolic conditions within the first few years postpartum.

A large Brazilian study suggests colder temperatures may increase cardiovascular hospitalizations, while regional climate differences did not appear to change the association.

GLP-1 receptor agonists are linked to sustained weight loss, improved blood glucose and lipid measures, and reductions in certain inflammatory marker levels among patients with rheumatic diseases.

In the randomized NEXAF trial, a 1-year personalized exercise program reduced atrial fibrillation burden by 45% and lowered atrial fibrillation-related hospitalizations.

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