Weight loss is not enough to treat dyslipidemia in women

Published Date: 06 Mar 2023

Obesity continues to exist around the world despite the risk to health and death from illness and disease.

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Once-daily oral orforglipron offers an effective weight-loss option for adults aged 65 years or older with overweight or obesity, regardless of type 2 diabetes status.

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The Illuminating Intersection of Art History and Medicine

Doctors who study ‘medical humanities’ have gained a deeper grasp of how classic works influence and intertwine with modern practice. And they’re better doctors for it.

Simplified Risk Score Predicts Coronary Calcium on CTA

A simplified risk calculator based on age, sex, and ethnicity correlates with coronary artery calcification and the severity of coronary artery stenosis on CCTA to guide cardiac CT protocol selection.

Some Comorbidities Tied to Greater Postbariatric Weight Loss

The presence of metabolic syndrome or chronic obstructive pulmonary disease is associated with a greater total weight loss at 1 year after bariatric surgery in patients with severe obesity.

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Home visits — once common and now resurging — flip the dynamic, as the clinician becomes a guest in the patient's home. Experts say as both learn more about each other than is possible in-office, trust can build.

Hidden Body Fat Threatens Male Fertility

Higher body fat percentage, rather than BMI, is associated with reduced sperm count and disrupted reproductive hormone levels in men.

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Todays Updates

Residency Reverse: When the Patient's Home Is the Office

Home visits — once common and now resurging — flip the dynamic, as the clinician becomes a guest in the patient's home. Experts say as both learn more about each other than is possible in-office, trust can build.

Hidden Body Fat Threatens Male Fertility

Higher body fat percentage, rather than BMI, is associated with reduced sperm count and disrupted reproductive hormone levels in men.

The Dose Is Too High: Rethinking TKI Dosing

Standard TKI doses are often too high for long-term care. Dr Mark Kris shares his strategy for smart dose reductions that protect patient outcomes.

Optimizing Therapy in Early Stage HER2+ Breast Cancer

Cure rates are climbing, and so is the complexity of getting there. Dr Yara Abdou takes a closer look at optimizing HER2+ early-stage breast cancer therapy.

What I Wish I Knew Before Starting a Direct Primary Care

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Once-daily oral orforglipron offers an effective weight-loss option for adults aged 65 years or older with overweight or obesity, regardless of type 2 diabetes status.

A call to study weight-loss drugs’ effects on pregnancy outcomes; why light physical activity could be key to public health; and what treadmill testing may reveal in aortic stenosis.

Health ‘optimization’ is all the rage. Doctors say some patients may be taking things too far — here’s what they’re doing about it.

Doctors who study ‘medical humanities’ have gained a deeper grasp of how classic works influence and intertwine with modern practice. And they’re better doctors for it.

A simplified risk calculator based on age, sex, and ethnicity correlates with coronary artery calcification and the severity of coronary artery stenosis on CCTA to guide cardiac CT protocol selection.

The presence of metabolic syndrome or chronic obstructive pulmonary disease is associated with a greater total weight loss at 1 year after bariatric surgery in patients with severe obesity.

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FDA Panel Votes Against DMD Therapy Deramiocel

In a 9-3 vote, an FDA advisory committee concluded that the available evidence does not support deramiocel's efficacy for treating cardiomyopathy in Duchenne muscular dystrophy.

Lipid Profile May Affect Heart Risks of Hormone Therapy

Baseline low-density lipoprotein cholesterol levels may help stratify heart risks in postmenopausal women starting oral hormone therapy, a study finds.

Assessing Function in AF: Physical Performance Tool Reliable

A multidimensional test capturing upper and lower limb function reveals lower functional capacity relevant to daily life activities in patients with atrial fibrillation vs healthy individuals.

Obesity Goes Underdiagnosed Even as Comorbidities Increase

Adults with elevated BMI in the US and Japan remain underdiagnosed for obesity, even as interrelated disease rates stay high, according to a large observational study.

Oral Propranolol Remains Standard for Infantile Hemangioma

No alternative treatment proved statistically superior to oral propranolol for infantile hemangioma in this network meta-analysis.

Pulmonary Vascular Changes Tied to Heart Failure

Structural changes in pulmonary blood vessels correlate with cardiac dysfunction and elevated pulmonary pressure in older adults, study finds.

CKM Syndrome Calls for Team-Based Care

New CKM guidelines urge clinicians to stop treating the heart, kidneys, and metabolism separately and instead manage risk through coordinated, stage-based care.

The Physician Lunch Break Is Dead — & Something Died With It

Doctors once bonded over shared meals. Today, lunch is a rushed snack between patients — or nothing at all. These doctors say we lost something vital along the way.

A Shooter Opens Fire at Tourists and a Doctor Must Step In

A doctor and paramedic husband scramble to help the wounded when a mass shooter opens fire atop a historical pyramid in Mexico.

No One Workout Beats Every Metabolic Risk

A network meta analysis of 53 trials finds that no single exercise modality improves all components of metabolic syndrome, supporting phenotype tailored prescriptions.

How to Confirm Patients Understand Prescription Instructions

Structured communication techniques, including teach back and plain language, can help reduce medication errors and support better adherence to treatment.

Statins Tied to Fewer Failures After Retina Fixes

People taking statins have about half the rate of sight-threatening proliferative vitreoretinopathy and need another operation after surgery to fix retinal detachment.

Ex-Mayo AI Exec Sues, Says She Was Fired for Whistleblowing

The lawsuit highlights the oversight role medical institutions play in determining whether AI tools are safe and appropriate for patient care and research.

Early TAVI Cost-Effective in Asymptomatic Aortic Stenosis

Early transcatheter aortic valve implantation is projected to reduce healthcare costs and improve outcomes compared with watchful waiting in patients with asymptomatic severe aortic stenosis.

Patients With Seizures Face Higher Cardiovascular Risk

Patients with late-onset seizures have a higher risk for major ischaemic cardiovascular disease or death than those without seizures.

New Inclisiran Therapy Shows Reduction in LDL Cholesterol

New lipid-lowering therapy, administered subcutaneously just twice a year, offers significant and sustained reduction of LDL-C across a diverse group of patient populations.

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