FDA panel backs Pfizer's RSV vaccine for US adults

Published Date: 02 Mar 2023

In a tough vote, advisers to the US Food and Drug Administration (FDA) on Tuesday approved the RSV vaccine for Americans over 60.

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Comorbid Fibromyalgia Tied to Falls in Lupus Patients

Patients with lupus who also have fibromyalgia face substantially higher risks for falls and fractures than those with only lupus, a recent study shows.

Healthy Births After CAR T Therapy in Autoimmune Diseases

Women with autoimmune diseases who receive CAR T-cell therapy have uncomplicated pregnancies without disease relapse, delivering healthy infants at full term.

Arkansas Shows Highest Seroprevalence of Alpha-Gal Syndrome

Alpha-gal syndrome is not a nationally reportable condition, so true burden remains unclear.

Antihistamines Fail to Relieve Eczema Symptoms

Oral antihistamines added to standard atopic dermatitis treatment result in detectable but clinically unimportant reductions in eczema severity and itch and may cause cognitive impairment.

Genetic Clues May Help Identify Obesity Risk Earlier

Population-specific genomic projects may help refine obesity risk scores and support more individualized interventions.

Half of Metastatic Skin Cancer Arises From Low-Stage Tumours

Nearly half of metastatic cutaneous squamous cell carcinoma cases arise from low-stage primary tumours, even when treatment is adequate, a nationwide analysis in Netherlands shows.

Todays Updates

Defibrotide Prophylaxis May Reduce SOS Risk After HSCT

A study evaluates whether defibrotide prophylaxis during HSCT reduces the risk for sinusoidal obstruction syndrome in children with relapsed or refractory B-ALL receiving prior inotuzumab.

Todays Updates

Defibrotide Prophylaxis May Reduce SOS Risk After HSCT

A study evaluates whether defibrotide prophylaxis during HSCT reduces the risk for sinusoidal obstruction syndrome in children with relapsed or refractory B-ALL receiving prior inotuzumab.

Latest News

Patients with lupus who also have fibromyalgia face substantially higher risks for falls and fractures than those with only lupus, a recent study shows.

Women with autoimmune diseases who receive CAR T-cell therapy have uncomplicated pregnancies without disease relapse, delivering healthy infants at full term.

Alpha-gal syndrome is not a nationally reportable condition, so true burden remains unclear.

Oral antihistamines added to standard atopic dermatitis treatment result in detectable but clinically unimportant reductions in eczema severity and itch and may cause cognitive impairment.

Population-specific genomic projects may help refine obesity risk scores and support more individualized interventions.

Nearly half of metastatic cutaneous squamous cell carcinoma cases arise from low-stage primary tumours, even when treatment is adequate, a nationwide analysis in Netherlands shows.

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Diet Strategy May Affect Growth With Food Allergies

Children with non-IgE-mediated food allergies managed with dietary interventions show improved growth trajectories, particularly in BMI-for-age z-scores.

Chronic Pain Conditions Linked to Risk for Dry Eye Disease

Chronic pain is associated with a significantly increased risk for developing dry eye disease over 3 years, a study finds.

‘This Cannot Be Right’: These Cells Break Immunology’s Rules

Researchers witness macrophages nibbling bits of living cells and using them to activate CD8 T cells — violating immunology dogma and begging the question: Why?

Deep Dive: JAK Inhibitors: Prescribing & Clinical Decision-Making

Ten agents, six specialties, and a complex safety landscape. This deep dive breaks down selectivity profiles, boxed warning nuances, and clinical selection criteria for the modern JAK inhibitor class.

Early Respiratory Infections Linked to Childhood AD Risk

Children with a higher burden of early-life respiratory infections show a dose-dependent increase in the risk for atopic dermatitis.

Ebola Patient Discharged From Frankfurt Hospital After Full Recovery

A U.S. citizen who became infected with ⁠the Ebola virus in Democratic Republic of Congo was ⁠discharged from Frankfurt University Hospital on Tuesday after ⁠making a full...

China's Innocare Says Psoriasis Oral Drug Shows 'consistent Treatment Effect' in Late-stage Trial

Chinese drugmaker Innocare Pharma said on Monday one of its experimental oral ⁠treatments for moderate-to-severe plaque psoriasis showed a "consistent treatment effect" in a...

An Older Woman With Refractory Hypoxemia

An older woman’s worsening dyspnea and upright desaturation lead to an unexpected diagnosis that required cardiac imaging and endovascular treatment.

Zanubrutinib May Benefit Patients With IgG4-Related Disease

Zanubrutinib monotherapy may help shrink inflamed glands, ease symptoms, and is generally well tolerated in patients with immunoglobulin G4-related head and neck disease, a phase 2 study shows.

Vitamin A Boosts Lung Function in Patients With Asthma

Vitamin A is linked to improved lung function both in children and adults with asthma; however, vitamin D shows the same benefit only in adults.

MetS May Up Risk for Clostridioides difficile Infection

Metabolic syndrome, obesity, and T2D each raise the odds of Clostridioides difficile infection — patients with diabetes facing the highest risk for adverse outcomes.

Childhood Cancer Incidence Linked With Socioeconomic Status

A Canadian study shows higher cancer incidence among children who live in affluent and residentially stable neighborhoods.

NICE Recommends Lung Machine to Ease Donor Shortage

A machine that keeps donated lungs alive outside the body has been conditionally recommended in new draft NICE guidance.

Measles and TB Return to Spain’s Emergency Rooms

With measles back in Spain and tuberculosis on the rise, emergency physicians are being urged to spot subtle clues early and isolate patients before spread begins.