First-in-human trial of CRISPR gene-editing therapy safely lowers cholesterol and triglycerides

Published Date: 11 Nov 2025

In a 15-patient, Phase 1, first-in-human trial, a one-time CRISPR-Cas9 gene-editing therapy safely reduced LDL cholesterol and triglycerides in people with difficult-to-treat lipid disorders, according to a preliminary late-breaking ...

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