Combination immunotherapy helps overcome melanoma treatment resistance

Published Date: 09 Nov 2025

Early data from a Phase 2 clinical trial show a combination of immunotherapy medications can activate a robust immune response and help overcome treatment resistance in patients with refractory melanoma.

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Women Face Longer Peer Review Delays

A PLOS Biology analysis finds papers led by women spend 7%-15% longer in peer review, a delay that can undermine promotion, funding, and career advancement for clinician-researchers.

Marijuana Use Tied to More Asthma Attacks in Young Adults

Young adults with asthma who inhale marijuana have a higher likelihood of asthma attacks, a new study finds.

Butterfly Network Gets FDA Clearance for AI Ultrasound Pregnancy Tool

Butterfly Network said on Monday it received U.S. regulatory clearance for an artificial intelligence-powered ultrasound ⁠tool that can estimate gestational age, a move the...

FDA Approves Higher Dose Of Genetic Disorder Drug for SMA

The U.S. Food and Drug Administration has approved a higher dose of Biogen's spinal muscular atrophy ⁠drug Spinraza, the company said on Monday, after rejecting it last...

Separate Hiring for Abortion Doctors Barred in Sicily

Italy's Constitutional Court bars Sicily from advertising jobs reserved for health workers willing to ⁠perform abortions, but it can find alternatives to safeguard access.

Real-Time Antimicrobial Stewardship May Aid Bacteremia Care

A real-time antimicrobial stewardship intervention may increase early switches from intravenous to oral antibiotics for nonstaphylococcal bloodstream infections, without changing clinical outcomes.

Todays Updates

Brexpiprazole Safe, Effective in Early-Episode Schizophrenia

Brexpiprazole is linked to reduced symptoms, improved functioning, and greater response compared with placebo in patients with early-episode schizophrenia, new research shows.

Oncology Care Model’s Net Losses Well Exceed Savings

But the CMS’s cancer-focused alternative payment model’s losses “mask successes” that should serve as lessons, experts say.

Todays Updates

Brexpiprazole Safe, Effective in Early-Episode Schizophrenia

Brexpiprazole is linked to reduced symptoms, improved functioning, and greater response compared with placebo in patients with early-episode schizophrenia, new research shows.

Oncology Care Model’s Net Losses Well Exceed Savings

But the CMS’s cancer-focused alternative payment model’s losses “mask successes” that should serve as lessons, experts say.

Latest News

A PLOS Biology analysis finds papers led by women spend 7%-15% longer in peer review, a delay that can undermine promotion, funding, and career advancement for clinician-researchers.

Young adults with asthma who inhale marijuana have a higher likelihood of asthma attacks, a new study finds.

Butterfly Network said on Monday it received U.S. regulatory clearance for an artificial intelligence-powered ultrasound ⁠tool that can estimate gestational age, a move the...

The U.S. Food and Drug Administration has approved a higher dose of Biogen's spinal muscular atrophy ⁠drug Spinraza, the company said on Monday, after rejecting it last...

Italy's Constitutional Court bars Sicily from advertising jobs reserved for health workers willing to ⁠perform abortions, but it can find alternatives to safeguard access.

A real-time antimicrobial stewardship intervention may increase early switches from intravenous to oral antibiotics for nonstaphylococcal bloodstream infections, without changing clinical outcomes.

News All Time

World’s Best Hospitals Ranking Puts Mayo Back at No. 1

A new global hospital ranking spanning 32 countries places Mayo Clinic first and highlights strong performances from hospitals in Germany, Switzerland, and Austria.

How Babies Process Pain — and Sugar’s Role in Relieving It

Mounting evidence backs sucrose as an analgesic for newborns — yet their experience of pain remains mysterious.

Environmental Pollution From Pharmaceuticals Raises Concern

Pharmaceutical residues increasingly enter ecosystems across the drug life cycle, prompting calls for coordinated global action grounded in One Health principles.

Newer Groundwater Linked to Increased PD Risk

Drinking water sourced from newer groundwater or carbonate aquifers is linked to a significantly increased risk for Parkinson’s disease, a new study shows.

AAN Issues Guidance on Consumer Wearables in Neurologic Care

New AAN guidance examines how consumer wearable devices can support neurologic care, including epilepsy monitoring and sleep tracking — while cautioning that many of them are insufficiently validated.

When Hearing Fails, Vision Rehab Falls Short

Patients with hearing impairment who receive vision rehabilitation are 42% less likely than those with normal hearing to achieve a meaningful functional improvement, a recent study shows.

AHS Recommends Annual Migraine Screening for Girls and Women

A new recommendation from the American Headache Society calls for annual migraine screening as part of preventive care for girls and women — from adolescence through menopause.

Biologics Don’t Promote Respiratory Infections

Reassuring data support the safety of biologics as an option for asthma care.

Biologics, Phototherapy in Psoriasis: Cost-Benefit Compared

A simulated analysis in psoriasis highlights divergent patient and payer incentives and inconsistent coverage strategies behind barriers to phototherapy uptake.

Spirituality Linked to Lower Risk for Substance Misuse

Integrating spirituality into patient care might hold potential for substance use prevention and recovery, a new meta-analysis shows.

GSK Gets US FDA Approval for Expanded Use Of RSV Vaccine

British drugmaker GSK said on Friday the U.S. Food and Drug ⁠Administration has expanded the approved age range for its respiratory syncytial virus vaccine, ⁠Arexvy, to...

WHO Confirms 18 Attacks on Healthcare Sites in Iran

The World Health Organization said on Wednesday that it has verified 18 attacks on healthcare centers ⁠in Iran since the start of the U.S. and Israel war on Iran.

How Can First-Year Residents Avoid Clinical Errors?

Experts say that many early residency mistakes stem from structural factors such as workload, supervision, and training environment, rather than from individual performance.

Dry Powder Inhaler May Reduce COPD Exacerbations

In patients with COPD, starting the umeclidinium-vilanterol dry powder inhaler may lower the risk for exacerbations compared with starting glycopyrrolate-formoterol or tiotropium-olodaterol inhalers.

Add-On Vancomycin Taper May Reduce C difficile Recurrence

In patients with a first episode or first recurrence of Clostridioides difficile infection, adding a vancomycin taper after the standard 14-day course may delay or lower the risk for recurrence.

Donna Ockenden to Lead Review of Leeds Maternity Failures

An independent review will examine maternity and neonatal services at Leeds Teaching Hospitals after repeated safety failures.

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