With ubituximab, a high percentage of patients maintained no signs of disease activity.

Published Date: 01 Mar 2023

After receiving ublituximab treatment, the majority of patients with relapsing multiple sclerosis showed that they could achieve and maintain no evidence of disease activity.

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Precision medicine intervention found to ease symptoms of a depression biotype

Depression is one of the most widespread mental health disorders worldwide, characterized by persistent feelings of sadness, a loss of interest in everyday activities, dysregulated sleep or eating patterns and other impairments. ...

How brain lipids help neurons communicate and protect themselves

A University of Alberta research team has discovered a new function for brain molecules known as gangliosides, offering potential new targets for the treatment of Huntington's and other genetic neurological diseases.

Brain pathway may fuel both aggression and self-harm

Aggression and self-harm often co-occur in individuals with a history of early-life trauma—a connection that has largely been documented by self-reporting in research and clinical settings. Adding to this connection, individuals ...

Abnormal repetitive behaviors in mice are associated with oxidative stress

Abnormal repetitive behaviors in mice are strongly linked to multiple biomarkers of oxidative stress, which occurs when antioxidants cannot counteract the effects of harmful molecules in the body, according to a study published ...

Blood markers linked to post-concussion symptoms in teens

Levels of certain biomarkers in the blood are associated with symptom severity during recovery from concussion in adolescents—with some significant differences between male and female patients, reports a study in the Journal ...

Caricature-inspired brain mapping method sharpens forecasts of cognitive and emotional traits

Caricature artists exaggerate distinctive features of an individual, deepening a cleft chin or multiplying freckles. Yale researchers have now applied a similar approach to maps of neural connections, emphasizing individual ...

Todays Updates

Combination treatment may help cut lifelong ibrutinib for chronic lymphocytic leukemia patients

Chronic lymphocytic leukemia (CLL) is the most prevalent adult leukemia in the Western Hemisphere, affecting approximately 200,000 people in the United States.

Study shows supervised exercise improves strength, physical performance in patients with advanced breast cancer

Aerobic and resistance exercise can significantly improve physical performance in patients living with metastatic breast cancer, according to new results presented at the Advanced Breast Cancer Eighth International Consensus ...

Todays Updates

Combination treatment may help cut lifelong ibrutinib for chronic lymphocytic leukemia patients

Chronic lymphocytic leukemia (CLL) is the most prevalent adult leukemia in the Western Hemisphere, affecting approximately 200,000 people in the United States.

Study shows supervised exercise improves strength, physical performance in patients with advanced breast cancer

Aerobic and resistance exercise can significantly improve physical performance in patients living with metastatic breast cancer, according to new results presented at the Advanced Breast Cancer Eighth International Consensus ...

Latest News

Depression is one of the most widespread mental health disorders worldwide, characterized by persistent feelings of sadness, a loss of interest in everyday activities, dysregulated sleep or eating patterns and other impairments. ...

A University of Alberta research team has discovered a new function for brain molecules known as gangliosides, offering potential new targets for the treatment of Huntington's and other genetic neurological diseases.

Aggression and self-harm often co-occur in individuals with a history of early-life trauma—a connection that has largely been documented by self-reporting in research and clinical settings. Adding to this connection, individuals ...

Abnormal repetitive behaviors in mice are strongly linked to multiple biomarkers of oxidative stress, which occurs when antioxidants cannot counteract the effects of harmful molecules in the body, according to a study published ...

Levels of certain biomarkers in the blood are associated with symptom severity during recovery from concussion in adolescents—with some significant differences between male and female patients, reports a study in the Journal ...

Caricature artists exaggerate distinctive features of an individual, deepening a cleft chin or multiplying freckles. Yale researchers have now applied a similar approach to maps of neural connections, emphasizing individual ...

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Study pinpoints source of free radicals in the brain that may fuel dementia

Free radicals generated at a specific site in non-neuronal brain cells called astrocytes may promote dementia, according to a Weill Cornell Medicine study. These findings, published in Nature Metabolism, demonstrated that ...

Significant variations in survival times of early onset dementia by clinical subtype

The survival rates of people with early onset dementia—diagnosed before the age of 65—vary considerably by clinical type, but sex, age, family history and co-existing conditions aren't specific risk factors, finds research ...

Personalized care can ease Parkinson's pain

Every 27 minutes, someone in Australia is diagnosed with Parkinson's disease. Best known for its tremors, movement and balance issues, it also brings another, often overlooked burden—persistent pain.

Detailed map of the developing human brain opens new pathways for Parkinson's treatment

Scientists from Duke-NUS Medical School and their collaborators have created one of the most comprehensive single cell maps of the developing human brain. The atlas captures nearly every cell type, their genetic fingerprints, ...

Reduced synapse protein SNAP 25 found in patients with major depressive disorder and schizophrenia

People with major depressive disorder or schizophrenia have been found to have lower levels of the synaptic protein "SNAP-25" in their cerebrospinal fluid, according a study by University Medicine Halle that included more ...

Massive database maps links between brain development and mental health

A new large-scale, open data resource from the Perelman School of Medicine and collaborators helps researchers link brain development with mental health disorders.

The right dose for the brain: Selenomethionine's role in protecting dopaminergic neurons

Dopamine is often called the brain's "motivation molecule," but for me, it represents something deeper, a window into how fragile our neurons can be. The cells that produce dopamine, known as dopaminergic neurons, are among ...

Exploring the relationship between sleep and diet

Sleep patterns and eating habits can influence each other, but the link between these behaviors remains unclear. In a new JNeurosci paper, researchers led by William Ja, from the Herbert Wertheim UF Scripps Institute for ...

Small brain region linked to schizophrenia risk through unique gene changes

New research published in the American Journal of Psychiatry provides new molecular insights into the role of the habenula, a pea-sized brain region that helps regulate motivation and mood, in contributing to the risk of ...

Prenatal exposure to specific fine particles linked to autism risk

A multi-institutional team including Health Canada researchers has found that prenatal air exposure to specific particulate matter components and early-life ozone is associated with autism spectrum disorder in Ontario children.

Families pay thousands for an unproven autism treatment: Researchers say we need ethical guidelines

Over the last decade, clinics have popped up across Southern California and beyond advertising something called magnetic e-resonance therapy, or MERT, as a therapy for autism.

Even modest amounts of physical activity may slow Alzheimer's disease among at-risk older adults

Increasing your steps by even a little bit may help slow down the progression of Alzheimer's disease among people at heightened risk, according to a new study. In a paper published in Nature Medicine, Mass General Brigham ...

Optimal cardiovascular health among people with type 2 diabetes may offset dementia risk

Having optimal cardiovascular health may offset the risk of developing mild cognitive impairment and dementia for people with type 2 diabetes (T2D), even among those with a high genetic risk for cognitive decline, according ...

Imaging study shows how brains go off-track in rare childhood disorder

Researchers at the VIB-UAntwerp Center for Molecular Neurology have visualized how brain network development is altered in a model of KCNQ2-related developmental and epileptic encephalopathy, a rare childhood brain disorder. ...

'Frazzled' fruit flies help unravel how neural circuits stay wired

Florida Atlantic University neuroscientists have uncovered a surprising role for a protein named "Frazzled" (known as DCC in mammals) in the nervous system of fruit flies, showing how it helps neurons connect and communicate ...

Neuronal hyperactivity and broader tuning linked to altered sound processing in autism model rats

People with autism spectrum disorders commonly have difficulty processing sensory information, which can make busy, bright or loud settings—such as schools, airports and restaurants—stressful or even painful. The neurological ...

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