With ubituximab, a high percentage of patients maintained no signs of disease activity.

Published Date: 01 Mar 2023

After receiving ublituximab treatment, the majority of patients with relapsing multiple sclerosis showed that they could achieve and maintain no evidence of disease activity.

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Roche said it is initiating a late stage study for its ⁠gene therapy Elevidys following feedback from the European drug regulator.

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Immunotherapy Combo Shows Promise for Hodgkin Lymphoma

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An overview of MASLD, including the epidemiology, diagnostic approaches, and therapeutic options highlighting the cardiologists’ role in its multidisciplinary management.

Jan 30 2026 This Week in Cardiology

Listener feedback, huge news in the rapidly expanding world of PFA AF Ablation, obesity, and a beautiful trial studying an AI-enhanced diagnostic tool in the office are the topics discussed by John Mandrola, MD, in this week’s podcast.

Exogenous Ketones and Exercise Tolerance: KETO-HFpEF

A crossover trial to determine whether ketone ester improves exercise tolerance in HFpEF.

Feb 06 2026 This Week in Cardiology

Problems with the PREVENT score, a breakthrough in lipid-lowering therapy, a surprising benefit in stroke care, and more thoughts on statins and preventive care of heart disease are the topics John Mandrola, MD, discusses in this week’s podcast.

Frailty in CVD: Time for a Universal Definition!

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Latest News

The U.S. Food and Drug Administration should be more transparent when granting accelerated approval for certain drugs, influential drug pricing body, Institute for Clinical...

A newly identified recessive neurodevelopmental disorder may be among the most common genetic causes of intellectual disability and epilepsy, new research suggests.

Roche said it is initiating a late stage study for its ⁠gene therapy Elevidys following feedback from the European drug regulator.

Researchers report the first autopsy-confirmed case of Alzheimer's disease following suspected medical transmission, but experts say definitive causation may remain elusive.

Leading psychiatry groups say WHO guidance on ECT risks stigmatizing and reducing access to a safe, effective, and sometimes life-saving treatment for patients with severe mental illness.

Earlier bedtime and wake time and regular physical activity are associated with a significant reduction in ALS risk, a new study shows.

News All Time

Late Complications Common After CVT, Even After Recovery

Although a majority of patients with cerebral venous sinus thrombosis achieve independence, 1 in 3 may develop delayed complications such as seizures, a study shows.

Activity Trackers May Predict MS Progression

Reduced daytime physical activity, as measured with wearable trackers, is tied to increased risk for multiple sclerosis progression and brain atrophy, new research shows.

WHO Warns Of Health Risks From 'Black Rain' in Iran

The World Health Organization warned on Tuesday that the 'black rain' and toxic compounds in the air in Iran after strikes on ⁠oil facilities could cause respiratory problems.

Wildfire Smoke Tied to Higher Stroke Risk, Greater Severity

Short-term surges in air pollution from wildfire smoke have been linked to a greater incidence and severity of stroke.

Therapeutic Research in Alzheimer’s Disease: What Is New?

Long-term extension trial results with donanemab suggest a widening separation in cognitive decline through 36 months in early Alzheimer’s disease.

Reframing Dyslexia: Ancient Genes, Modern Skill

Study argues to move beyond ‘reading genes’ — focus on conserved neural-development networks in humans to improve early screening and identify therapeutic leads.

Adults With IDDs Face ‘Mental Health Crisis’

Adults with IDDs face disproportionately higher rates of anxiety and depression and barriers to care, prompting researchers to characterize the situation as a ‘mental health crisis.’

Positive Topline Results for Efgartigimod in Ocular MG

Efgartigimod led to statistically significant improvement in key symptoms of ocular myasthenia gravis compared with placebo in a phase 3 trial.

Smoking + Parkinson's: Lower Disease Risk, Higher Mortality

A large nationwide study revisits the smoking-Parkinson's paradox, linking current smoking to lower disease risk but linking quitting to lower all-cause mortality.

Stem Cell Therapy Safe, Feasible in Spina Bifida

A first-in-human trial shows the feasibility and safety of delivering placenta-derived stem cells during prenatal myelomeningocele repair.

Does Caring for Grandchildren Slow Cognitive Decline?

Grandmothers who care for grandchildren show slower cognitive decline over time than non-caregivers do.

Teen Cannabis Use Tied to Increase in Serious Mental Illness

A new study shows that teens with past-year cannabis use are twice as likely to be diagnosed with psychotic or bipolar disorders within 2 years of first use.

Fertility Treatments Linked to Higher Med Use in Offspring

Children conceived through medically assisted reproduction have higher out-of-hospital healthcare utilization including mental health medications.

Lifetime Risk Estimates for Dementia, MCI: New Data

Mild cognitive impairment before dementia is common in older adults, with women facing a higher lifetime burden and Black adults an earlier onset, new research shows.

Fibromyalgia-PTSD Link Shows Bidirectional Relationship

Research suggests a bidirectional relationship between posttraumatic stress disorder and fibromyalgia in military service members exposed to combat environments.

Redefining Cognitive Assessment With One Blood Test

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