Study: "Profound" diagnoses of autism are far outnumbered by milder cases.

Published Date: 26 Apr 2023

Health officials have wondered how many U.S. children are being diagnosed with autism as it becomes more common. S. How many children experience more severe symptoms like a very low IQ and verbal immaturity, and how many kids have relatively mild symptoms?

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Gene 'switch' reverses Alzheimer's risk in experimental model

University of Kentucky researchers have developed a new experimental model that could point the way toward more effective Alzheimer's disease treatments by targeting one of the brain's most important genes for risk and resilience.

Mild cognitive impairment, dementia risk up with increasing biological severity of Alzheimer's disease

For individuals who are currently cognitively unimpaired, the lifetime and 10-year absolute risk of mild cognitive impairment (MCI) and dementia increases with increasing amyloid positron emission tomography (PET) centiloid ...

What polymers can teach us about curing Alzheimer's disease

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Study shows over 90% of older adults with dementia undergo burdensome interventions in their final year

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Parents of neurodivergent kids need support. But those who need it most often wait longer

Parenting any young child is full of highs and lows. In addition to these, parents and caregivers of children with neurodevelopmental conditions such as autism and attention-deficit hyperactivity disorder (ADHD) are more ...

Next-generation microbiome medicine may transform Parkinson's treatment

The age-old advice to "trust your gut" could soon take on new meaning for people diagnosed with Parkinson's disease, thanks to a creative feat of bioengineering by researchers in the University of Georgia's College of Veterinary ...

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Anemia Correction Before Colorectal Surgery Yields No Postoperative Gains

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Bridging the Treatment Gap in Pediatric Psoriasis and PsA With Guselkumab, With Vimal H. Prajapati, MD Vimal H. Prajapati, MD

Prajapati discussed the impact of the expanded approval of guselkumab to pediatric PsO and psoriatic arthritis.

Sonelokimab Demonstrates Psoriatic Arthritis Improvements Over Placebo Victoria Johnson

Sonelokimab meets ACR50 primary endpoint in a phase 2 trial.

Todays Updates

Anemia Correction Before Colorectal Surgery Yields No Postoperative Gains

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Addressing Fibromyalgia Sleep and Pain With TNX-102 SL Approval: Q&A With Philip Mease, MD Philip J. Mease, MD

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The rheumatology month in review emphasizes new approvals and the latest comparative research.

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Q3 2025 saw several new first targeted therapies for rare and more individualized indications in a number of fields.

Q3 2025 Recap: Rheumatology News and Updates Victoria Johnson

Q3 2025 saw a number of exciting approvals and data on promising therapies in development.

Bridging the Treatment Gap in Pediatric Psoriasis and PsA With Guselkumab, With Vimal H. Prajapati, MD Vimal H. Prajapati, MD

Prajapati discussed the impact of the expanded approval of guselkumab to pediatric PsO and psoriatic arthritis.

Sonelokimab Demonstrates Psoriatic Arthritis Improvements Over Placebo Victoria Johnson

Sonelokimab meets ACR50 primary endpoint in a phase 2 trial.

Latest News

University of Kentucky researchers have developed a new experimental model that could point the way toward more effective Alzheimer's disease treatments by targeting one of the brain's most important genes for risk and resilience.

For individuals who are currently cognitively unimpaired, the lifetime and 10-year absolute risk of mild cognitive impairment (MCI) and dementia increases with increasing amyloid positron emission tomography (PET) centiloid ...

Researchers from Tokyo Metropolitan University have applied ideas from polymer physics to illuminate the mechanism behind a key pathology in Alzheimer's disease, the formation of fibrils of tau proteins. They showed that ...

A new study by researchers from Duke-NUS Medical School has revealed that almost all community-dwelling older adults with advanced dementia in Singapore experience at least one potentially burdensome intervention in their ...

Parenting any young child is full of highs and lows. In addition to these, parents and caregivers of children with neurodevelopmental conditions such as autism and attention-deficit hyperactivity disorder (ADHD) are more ...

The age-old advice to "trust your gut" could soon take on new meaning for people diagnosed with Parkinson's disease, thanks to a creative feat of bioengineering by researchers in the University of Georgia's College of Veterinary ...

News All Time

Quantifying the intensity of emotional response to sound, images and touch through skin conductance

When we listen to a moving piece of music or feel the gentle pulse of a haptic vibration, our bodies react before we consciously register the feeling. The heart may quicken and palms may sweat, resulting in subtle electrical ...

Brain's mechanical properties influence synapse formation and electrical signal development, study finds

In the brain, highly specific connections called synapses link nerve cells and transmit electrical signals in a targeted manner. Despite decades of research, how synapses form during brain development is still not fully understood.

Signal in the silence: Researchers uncover hidden potential in discarded MRI data

In every functional MRI scan, after the whir and pounding begins, there is a brief 10 to 20 seconds of stabilization as the machine's magnetic field settles into place. For decades, scientists have treated this period as ...

The link between the gut microbiome and autism is not backed by science, researchers say

There's no scientific evidence that the gut microbiome causes autism, a group of scientists argue in an opinion paper published in Neuron. They point to the fact that conclusions from past research that supported this hypothesis—including ...

New oral treatment may prevent dementia

Researchers from DANDRITE have played a central role in developing a new oral treatment that, for the first time ever, has shown promising results in a clinical trial involving patients—a breakthrough that appears capable ...

How income may shape risk of dementia

People with lower incomes and people from racial and ethnic historically underrepresented groups in clinical studies are more likely to have modifiable risk factors for dementia, factors that could be changed to lower their ...

LSD microdosing reduces depression scores without major side effects, clinical trial finds

University of Auckland researchers report that an 8-week, twice-weekly LSD microdosing regimen for major depressive disorder was feasible and well-tolerated, with Montgomery-Åsberg Depression Rating Scale (MADRS) scores ...

Newly discovered RNA molecule could limit protein aggregation and prevent neuronal damage

Neurodegenerative diseases, such as Alzheimer's disease and dementia, are medical conditions that entail the progressive loss of neurons and a decline in brain function. Past studies have found a link between these diseases ...

Research in mice reveals brain cells that drive—and prevent—anxiety

Anxiety disorders are some of the most common mental health conditions in America, affecting about one in five people nationwide. But much remains unknown about the roots of anxiety in the brain. Now, research at the University ...

Findings reveal role of FBXO21 in axon degeneration

NMNAT2 is a key protein required for axon integrity whose rapid depletion following axon injury triggers Wallerian degeneration. The molecular mechanism controlling NMNAT2 turnover in neurons has not been fully understood. ...

Chemical compound holds potential against Alzheimer's disease

A team of researchers at the Federal University of ABC (UFABC) in Brazil has developed a new chemical compound with the potential to treat Alzheimer's disease. The research involved computer simulations (in silico), cell ...

Alzheimer's risk calculator could spot danger years before symptoms begin

Mayo Clinic researchers have developed a new tool that can estimate a person's risk of developing memory and thinking problems associated with Alzheimer's disease years before symptoms appear.

Infants born with hearing loss show disruptions in brain design, underscoring the urgency of intervention

Infants born deaf or hard of hearing show adverse changes in how their brains organize and specialize, but exposure to sound and language may help them develop more normally, according to new research.

Research reveals shared genetic roots for psychiatric and neurological disorders

Researchers from the Center for Precision Psychiatry at the University of Oslo and Oslo University Hospital have discovered extensive genetic links between neurological disorders like migraine, stroke and epilepsy, and psychiatric ...

Drug candidate slows motor neuron disease progression and preserves muscle function in preclinical study

A drug candidate found to protect nerve cells damaged by motor neuron disease (MND), could offer new hope to people living with the devastating condition.

Brain activity goes to extremes in soccer fans, neuroimaging reveals

Studying brain patterns in soccer fans, researchers found that certain circuit regions of the brain were activated while viewing soccer matches involving their favorite team, triggering positive and negative emotions and ...

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