Researchers show that an efficacious breast cancer drug can be reconstituted from one that is susceptible to resistance.

Published Date: 07 Feb 2024

Targeting a protein known as TACC3 (transforming acidic coiled-coil containing protein 3) has been demonstrated by researchers at MUSC Hollings Cancer Center to restore the effectiveness in a recent paper published in Cancer Research.

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Delays in Visa Program Threaten Hundreds of Doctors

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Prime Minister Keir Starmer said on Wednesday that Britain's biggest company AstraZeneca would invest 300 million pounds ($405 ⁠million) in the country, after pausing...

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Germany Risks Missing Out on New Drugs, AstraZeneca CEO Says

AstraZeneca's CEO said Germany risks missing out on new drugs that ⁠the drugmaker plans to launch if the nation sticks with plans to keep pharmaceutical spending in check.

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EMA Backs Breast Cancer SERD After FDA No Vote

The recommendation follows phase 3 data showing longer progression-free survival when patients switched to camizestrant plus a CDK4/6 inhibitor.

Datopotamab Deruxtecan Earns New Breast Cancer Indication

The antibody drug conjugate was approved by the FDA for certain patients with triple-negative breast cancer.

Todays Updates

EMA Backs Breast Cancer SERD After FDA No Vote

The recommendation follows phase 3 data showing longer progression-free survival when patients switched to camizestrant plus a CDK4/6 inhibitor.

Datopotamab Deruxtecan Earns New Breast Cancer Indication

The antibody drug conjugate was approved by the FDA for certain patients with triple-negative breast cancer.

Latest News

Boston Scientific has issued an urgent recall to correct several heart devices after ⁠the U.S. Food and Drug Administration classified the action as its most serious recall,...

Prolonged HHS J-1 waiver backlogs leave hundreds of foreign-trained doctors facing departure this summer, threatening care in underserved areas, immigration attorneys warn.

Prime Minister Keir Starmer said on Wednesday that Britain's biggest company AstraZeneca would invest 300 million pounds ($405 ⁠million) in the country, after pausing...

Europe risks falling behind the US and China in pharma innovation because of bureaucracy and government policies threatening ⁠jobs, Roche CEO Thomas Schinecker warns.

U.S. health regulators announced a new program to speed up Medicare coverage for certain medical devices on ⁠Thursday, saying it would cut reimbursement timelines to as...

AstraZeneca's CEO said Germany risks missing out on new drugs that ⁠the drugmaker plans to launch if the nation sticks with plans to keep pharmaceutical spending in check.

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The Golden Handcuffs of Private Equity

Private equity firms are increasingly buying up smaller medical practices. Sometimes for the better, and sometimes not.

New Book Spotlights Medicine’s Emotional Side

A new anthology, Where It Hurts: Dispatches from the Emotional Frontlines of Medicine, explores how doctors process the day-to-day challenges of their careers.

Novel imaging approach may improve treatment for spinal cord injuries

Northwestern Medicine investigators have developed a new imaging approach to more accurately assess blood flow in the spinal cord, a method that could be used to better inform treatment for neurological diseases and injuries, ...

Tirzepatide may only temporarily suppress brain 'food noise' activity

A rare glimpse into the brain activity of a patient with obesity and loss of control eating on tirzepatide, marketed as Mounjaro and Zepbound, revealed that the medication suppresses signaling in the brain's "reward center" ...

Supercomputer simulation is changing how we study the brain

Harnessing the muscle of one of the world's fastest supercomputers, researchers have built one of the largest and most detailed biophysically realistic brain simulations of an animal ever.

AI tool creates digital twins of patients to predict their future health

A new artificial intelligence tool that can create virtual representations of patients and predict individual health trajectories has been hailed a potential gamechanger for the clinical trial sector.

New tool predicts graft failure after kidney transplant

Researchers at The Johns Hopkins Medicine say they have developed a new electronic medical records-based tool that should help doctors predict which patients are most at risk of losing a transplanted kidney graft.

How are patients using health care chatbots? Study finds some 'eye-openers'

A health care chatbot can be a patient's first point of contact for some sensitive conversations from mental health to billing, a new CU Anschutz study has found.

New study reveals high rates of fabricated and inaccurate citations in LLM-generated mental health research

A new study published in the journal JMIR Mental Health by JMIR Publications highlights a critical risk in the growing use of Large Language Models (LLMs) like GPT-4o by researchers: the frequent fabrication and inaccuracy ...

A unified model of memory and perception: How Hebbian learning explains our recall of past events

A collaboration between SISSA's Physics and Neuroscience groups has taken a step forward in understanding how memories are stored and retrieved in the brain. The study, recently published in Neuron, shows that distinct perceptual ...

Ovarian tissue preservation enables future fertility for young woman with cancer

In patients of reproductive age who have cancer, fertility preservation for potential children in the future should be a high priority. A practice article published in the Canadian Medical Association Journal describes the ...

Malaria rapid diagnostic test 'not fit for purpose,' international study claims

An international study published in the Malaria Journal claims that a widely used test for detecting malaria is delivering too many inaccurate false-negative results and is "not fit for purpose."

Simple test brings clarity and hope for families with inherited neuropathy

A new, inexpensive urine test that measures two sugar alcohols, sorbitol and xylitol, is making it easier, faster, and far less expensive to identify a common inherited nerve disorder called SORD-related neuropathy. The test, ...

Would you put period blood on your face? What science says about 'menstrual masking'

In the ever-evolving world of beauty trends, few have sparked as much debate—and discomfort—as "menstrual masking." This is the practice of applying menstrual blood to the skin, usually the face, as a form of DIY skincare.

Reaching the unreachable: Endoscopy technique opens route to deep lung tumors

Researchers at the University of Osaka have engineered a novel technique, balloon-assisted bronchoscope delivery (BDBD), to guide endoscopes to small, early-stage lung cancers hidden deep within the periphery of the lungs.

Healing the heart after a heart attack with a biodegradable patch

A new patch developed by Texas A&M University researcher Dr. Ke Huang may offer a way to help the heart heal after a heart attack. The patch uses a unique microneedle system to deliver a therapeutic molecule directly to damaged ...

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