Basal cell carcinoma's low immunogenicity linked to suppression of antigen presentation from its cell of origin

Published Date: 23 Apr 2025

Compromised antigen presentation ranks among the top mechanisms that render cancers non-immunogenic (non-responsive to immune-based therapies). Despite harboring the highest tumor mutational burden of all cancers, basal cell ...

Read Full News

Latest News

Initial Prescription Duration May Shape Benzodiazepine Use

Longer durations of initial prescriptions are associated with prolonged use of benzodiazepines compared with durations of 7 days or less, a large cohort study shows.

Alcohol’s Health Myth Is Over. How to Tell Patients

The science on alcohol has changed dramatically. Here’s how experts say physicians can explain why older advice no longer holds up — and counsel patients without judgment.

US House Committee Opens Investigation Into Merck, AbbVie China Drug Trials

The chair of the U.S. House Select Committee on China opened national security investigations into whether five drugmakers including Merck and AbbVie have been involved in...

Bepirovirsen Achieves Functional Cure in HBV Phase 3 Trial

In patients with chronic hepatitis B infection, bepirovirsen achieves significantly higher rates of functional cure than placebo after discontinuation of nucleoside or nucleotide analog therapy.

Retina Care Visits Reveal High BP in Adults With Diabetes

Many adults with diabetes have uncontrolled or previously undiagnosed high blood pressure during their routine visits to retina clinics, prompting referrals and urgent follow-up, a study finds.

Venezuela Health System Strained After Earthquakes, WHO Says

Venezuela's healthcare system is under significant strain, ⁠the World Health Organization said on Tuesday, with some hospitals damaged and ⁠others missing staff after deadly...

Todays Updates

Enhancing Comprehensive Biomarker Testing and Biomarker-Directed Treatment Selection

Enhancing Comprehensive Biomarker Testing and Biomarker-Directed Treatment Selection

Advancing Care in ES-SCLC: Personalized Strategies, New Therapies, and Real-World Insights

Advancing Care in ES-SCLC: Personalized Strategies, New Therapies, and Real-World Insights

Adjuvant Combination for Kidney Cancer Gets FDA's Blessing

Belzutifan and pembrolizumab together reduced the risk of disease recurrence or death

FDA Approves Prostate Cancer Combo That Warranted Advisory Meeting

Capivasertib plus abiraterone combination lands indication for PTEN-deficient tumors

Talquetamab Regimens Boost Survival in Multiple Myeloma

"Combinations represent additional options for early-line treatment," researcher says

In High-Risk B-Cell ALL, Swapping Out Chemo for Blinatumomab Improves Outcomes

The bispecific T-cell engager also reduced toxicity in newly diagnosed kids

Timely 'Nudges' Can Help Encourage More End-of-Life Conversations in Cancer

A combination of clinician and patient prompts worked best, but talks remained infrequent

Todays Updates

Enhancing Comprehensive Biomarker Testing and Biomarker-Directed Treatment Selection

Enhancing Comprehensive Biomarker Testing and Biomarker-Directed Treatment Selection

Advancing Care in ES-SCLC: Personalized Strategies, New Therapies, and Real-World Insights

Advancing Care in ES-SCLC: Personalized Strategies, New Therapies, and Real-World Insights

Adjuvant Combination for Kidney Cancer Gets FDA's Blessing

Belzutifan and pembrolizumab together reduced the risk of disease recurrence or death

FDA Approves Prostate Cancer Combo That Warranted Advisory Meeting

Capivasertib plus abiraterone combination lands indication for PTEN-deficient tumors

Talquetamab Regimens Boost Survival in Multiple Myeloma

"Combinations represent additional options for early-line treatment," researcher says

In High-Risk B-Cell ALL, Swapping Out Chemo for Blinatumomab Improves Outcomes

The bispecific T-cell engager also reduced toxicity in newly diagnosed kids

Timely 'Nudges' Can Help Encourage More End-of-Life Conversations in Cancer

A combination of clinician and patient prompts worked best, but talks remained infrequent

Latest News

Longer durations of initial prescriptions are associated with prolonged use of benzodiazepines compared with durations of 7 days or less, a large cohort study shows.

The science on alcohol has changed dramatically. Here’s how experts say physicians can explain why older advice no longer holds up — and counsel patients without judgment.

The chair of the U.S. House Select Committee on China opened national security investigations into whether five drugmakers including Merck and AbbVie have been involved in...

In patients with chronic hepatitis B infection, bepirovirsen achieves significantly higher rates of functional cure than placebo after discontinuation of nucleoside or nucleotide analog therapy.

Many adults with diabetes have uncontrolled or previously undiagnosed high blood pressure during their routine visits to retina clinics, prompting referrals and urgent follow-up, a study finds.

Venezuela's healthcare system is under significant strain, ⁠the World Health Organization said on Tuesday, with some hospitals damaged and ⁠others missing staff after deadly...

News All Time

Colistin MIC Affects Outcomes in Gram-Negative Infections

In carbapenem-resistant gram-negative infections caused by pathogens for which the colistin MIC is 2 mg/L, the colistin-meropenem combination is linked to better clinical outcomes than colistin alone.

What 300,000 Implants Say About Light Adjustable Lens

An intraocular lens that can be adjusted after cataract surgery has better outcomes for meeting target vision than other lenses, but patient selection and involvement are key.

Parkinson’s Disease Deaths Decline Among Older US Adults

Death rates from Parkinson’s disease among US older adults decline in 2024 following a steady rise from 2014 to 2021, new data show.

Sri Lanka Battles Surge in Dengue Fever, With More Than 44,000 Cases So Far This Year

Sri Lanka is battling the worst outbreak of mosquito-borne dengue fever in years, with more than ⁠44,000 cases and 28 deaths recorded since January, an official said on...

More Than 70 Congo Medics Infected With Ebola Since Outbreak Started, WHO Says

A senior World Health Organization official said on Friday that 75 ⁠medics in the Democratic Republic of Congo had been infected with Ebola and 17 of ⁠them had died since...

US Progesterone Supplies Tighten as Menopause Treatment Demand Grows

U.S. supplies of progesterone are coming under strain, with patients, clinicians, and pharmacists reporting recent intermittent shortages of oral versions of the hormone...

Moderna's MRNA Flu Vaccine Backed by FDA Advisers

Advisers to the U.S. Food and Drug Administration on Thursday backed approval of Moderna's flu vaccine for adults aged 50 and older, saying its benefits outweigh its risks,...

Mycobacteria May Predict Graft Failure After Lung Transplant

Early isolation can be a biomarker for patients at increased risk for poor outcomes.

Safety Gaps Put Patients at Risk Across NHS Pathways

NHS patients may face delays in accessing specialist care because of accountability failures and data-sharing gaps across regional pathways, HSSIB has warned.

Moderna Flu Shot Data May Support Use in Older Adults, US FDA Staff Says

U.S. Food and Drug Administration staff reviewers said on Tuesday data demonstrating an immune response to Moderna's flu shot may support effectiveness in adults ⁠65 years...

Ebola Risk for World Cup Is 'Extremely Low', but US Is Ready, Experts Say

The risk that a traveler infected with Ebola could arrive in the United States during the 2026 World Cup tournament that kicked off last week is low but not zero, and if...

US Paying Almost $25,000 a Month to Store Unusable Contraceptives Stuck in Belgium

The United States is spending almost $25,000 every month to store contraceptives in Belgium that were originally bought for use in poorer nations but are ⁠now mainly...

RCPsych: Make Mental Healthcare a Priority, Not a Privilege

The UK must choose between investing in mental healthcare for all or accepting a postcode lottery, the outgoing RCPsych president warns.

VR May Help Curb Cravings in Substance Use Disorder

Virtual reality-based interventions are associated with significantly reduced cravings in patients with various substance use disorders, a new meta-analysis shows.

Infections Tied to Asthma Attacks on Benralizumab Therapy

In patients with eosinophilic asthma on benralizumab, attacks often feature airway neutrophilia, respiratory viruses, and microbiome shifts, indicating infections are a key cause of exacerbations.

EMA Holds Valproate Precautions Despite Mixed Evidence

EMA has found inconsistent data on developmental disorders in children of fathers using valproate before conception and retains existing precautions.

Recommended News For You

Advances in "next generation" photoactive cancer therapy

Do I qualify for a cancer clinical trial?

GuCS: Genitourinary Cancers Symposium

Study reveals link between new-onset type 2 diabetes and some obesity-related cancers

Nearly 6 Million Deaths From Five Major Cancer Types Averted Since 1975

The importance of breast cancer screening

Parents, teachers at Missouri school want answers after string of cancer diagnoses

Recommended Articles For You

Unlocking the Potential of Talquetamab: A Revolutionary Approach to Cancer Treatment 

Innovative Practices in Hematology in the Digital Era 

The Latest Research on Wiskott Aldrich Syndrome  

Revolutionizing Cancer Treatment: ESMO's Updated Recommendations for Tumour NGS 

Whats more on Hidoc Dr.

Medical Updates
KOL Videos
Surveys
Events

Daily news to keep you up to date

Gain valuable insights with our in-depth KOL Video discussions

Participate and win cash vouchers

Get updates on the latest events happening around the world
Featured News
Featured Articles
Featured Events
Featured KOL Videos

1.

Radioactive ion beams successfully treat animal tumors in study

2.

A computer-aided diagnostic system for improved detection of breast cancer.

3.

Ultrasound bras; HPV and thyroid cancer; language minimizing adverse events.

4.

Study reveals that older women frequently receive an incorrect breast cancer diagnosis.

5.

Durvalumab Plus BCG Earns FDA Nod for Bladder Cancer

1.

The Impact of Microadenoma on Hormonal Health

2.

Unlocking the Mysteries of the Axillary Vein: Exploring its Role in Human Anatomy

3.

ctDNA in Oncology: Transforming MRD Assessment, Disease Tracking, and Early Cancer Detection

4.

The Silent Danger of Hematoma: How to Identify and Treat This Potentially Serious Condition

5.

Revolutionizing Cancer Treatment: How Adoptive Cell Therapy is Overcoming Tumor Immune Evasion

1.

Asian Symposium on Advancement in Hematology and Oncology

2.

Asian Symposium on Advancement in Hematology and Oncology

3.

Asian Symposium on Advancement in Hematology and Oncology

4.

International Cancer Conference

5.

Asian Symposium on Advancement in Hematology and Oncology

1.

Revolutionizing Treatment of ALK Rearranged NSCLC with Lorlatinib - Part V

2.

Current Scenario of Blood Cancer- A Conclusion on Genomic Testing & Advancement in Diagnosis and Treatment

3.

Current Scenario of Blood Cancer- Genomic Testing & Advancement in Diagnosis and Treatment

4.

Newer Immunotherapies for Myeloma- A Comprehensive Overview- Part II

5.

Pazopanib Takes Center Stage in Managing Renal Cell Carcinoma - Part III

Fastest Growing Medical Platform for Doctors

Address :
Hidoc Dr. Inc. | Delaware C Corp | 1309 Coffeen Ave. Suite 1200, Sheridan WY, 82801

Phone :
+1-415-463-3094

Email :
anishagadia@hidoc.co

Quick Links

Drug DatabaseDrug InteractionDiseases Database
KOL VideosKnowledge HubQuizzes
Medical UpdatesEventsAbout Us

© Copyright 2026 Hidoc Dr. Inc.

Terms & Conditions - LLP | Inc. | Privacy Policy - LLP | Inc. | Account Deactivation
Home
Profile
Login
bot