Clinical trial finds RNA inhibitor effectively reduces 'bad cholesterol' in patients with cardiovascular disease

Published Date: 14 Feb 2025

The RNA inhibitor olpasiran significantly reduces a type of "bad cholesterol" that's associated with a high risk of cardiovascular events, according to results from an analysis by a Mount Sinai researcher of a Phase II trial.

Read Full News

Latest News

Non-opioid pain relief: Brain's 'cleanup crew' reveals a new target

Chronic pain is a daily reality for millions of Americans, interfering with their everyday activities and quality of life. An estimated 24.3% of adults in the United States experienced chronic pain in 2023, and current treatment ...

Clinical trial countries often left without new medicines they helped test

A new study led by Yale's Jennifer Miller, Ph.D., found that medicines are not physically accessible in many of the countries where they are tested for FDA approval. The findings were published in JAMA Internal Medicine.

New study identifies part of brain animals use to make inferences

Animals survive in changing and unpredictable environments by not merely responding to new circumstances, but also, like humans, by forming inferences about their surroundings—for instance, squirrels understand that certain ...

Researcher out to solve mystery of migraine

Often dismissed as a minor ailment, migraine is a debilitating neurological disease affecting hundreds of thousands of New Zealanders. At the University of Otago's School of Biomedical Sciences, world-leading research by ...

Why snake pee may be key to treating kidney stones and gout

Scientists think snakes and lizards could help them find new ways to prevent painful kidney stones and gout in people. And it all owes to an evolutionary trick.

Scientific researchers urge Congress to increase funding to the NIH as the shutdown ends

The record-breaking federal government shutdown marked yet another impediment to scientific research efforts at the Wistar Institute this year.

Todays Updates

Belgian Algorithm Reshapes Endometrial Cancer Care

A new Belgian algorithm may help clinicians choose adjuvant therapy more precisely in early endometrial cancer, moving beyond TNM staging alone.

Todays Updates

Belgian Algorithm Reshapes Endometrial Cancer Care

A new Belgian algorithm may help clinicians choose adjuvant therapy more precisely in early endometrial cancer, moving beyond TNM staging alone.

Latest News

Chronic pain is a daily reality for millions of Americans, interfering with their everyday activities and quality of life. An estimated 24.3% of adults in the United States experienced chronic pain in 2023, and current treatment ...

A new study led by Yale's Jennifer Miller, Ph.D., found that medicines are not physically accessible in many of the countries where they are tested for FDA approval. The findings were published in JAMA Internal Medicine.

Animals survive in changing and unpredictable environments by not merely responding to new circumstances, but also, like humans, by forming inferences about their surroundings—for instance, squirrels understand that certain ...

Often dismissed as a minor ailment, migraine is a debilitating neurological disease affecting hundreds of thousands of New Zealanders. At the University of Otago's School of Biomedical Sciences, world-leading research by ...

Scientists think snakes and lizards could help them find new ways to prevent painful kidney stones and gout in people. And it all owes to an evolutionary trick.

The record-breaking federal government shutdown marked yet another impediment to scientific research efforts at the Wistar Institute this year.

News All Time

Research gap discovered: 1 in 21 adults affected by mental disorders omitted from global health study

Mental disorders that cause physical symptoms are not included in a major health trends study, despite them impacting as many as 1 in 21 adults, researchers have found.

Scientists complete first drafts of developing mammalian brain cell atlases

A global consortium of scientists has created the first and most detailed "developmental maps" of the mammalian brain (from mouse to human) to date, taking the first critical steps in unraveling the mystery of early brain ...

Slowed by sound: Mouse model of Parkinson's disease shows noise affects movement

In the development of Parkinson's disease, it may not be a good idea to turn the amp to 11. High-volume noise exposure produced motor deficits in a mouse model of early-stage Parkinson's disease, and established a link between ...

'Molecular glues' and 'bumpers' offer new hope for precision medicines

New research led by the University of Minnesota Medical School demonstrates that molecules acting as "molecular bumpers" and "molecular glues" can rewire G protein-coupled receptor (GPCR) signaling, turning the cell's busiest ...

Astringent, sharper mind: Flavanols can trigger brain activity for memory and stress response

Astringency is a dry, puckering, rough, or sandpapery sensation in the mouth caused by plant-derived polyphenols. Polyphenols, including flavanols, are well known for risk reduction in cardiovascular diseases.

Opening the door to a vaccine for multiple childhood infections

A vaccine that tackles the bacteria that cause up to 200 million childhood infections every year could be possible, experts say.

Hundreds of animal studies on brain damage after stroke flagged for problematic images

A new study has identified over 240 scientific publications on animal models of hemorrhagic stroke that contain potentially problematic images, thereby raising concerns about the trustworthiness of the body of literature ...

Decentralized future: Expanding clinical trials by allowing people to participate from home

As the world becomes more digital, clinical research is evolving. One major change is the rise of decentralized clinical trials, or DCTs. Unlike traditional trials that require participants to visit hospitals or research ...

In drug trials, lack of oversight of research ethics boards could put Canadian patients at risk

New drug approvals by Health Canada are based on the results of clinical trials. But before clinical trials can go ahead, they need to be approved by ethics committees known as Research Ethics Boards (REBs).

Discovery of 'doorstop' for brain's electrical gates may open path to new therapies for neurodegenerative conditions

As information zings from cell to cell inside the brain, bursts of electricity spur its transmission. At Cold Spring Harbor Laboratory (CSHL), scientists have turned their attention to the tiny pores that let charged ions ...

WHO's priorities shaped by its reliance on grants from donor organizations, study suggests

The World Health Organization's (WHO's) priorities are being skewed by its increasing reliance on donations from organizations such as the Gates Foundation (previously known as the Bill and Melinda Gates Foundation), which ...

Opt-out organ donation policies may reduce organ supply

Every day, 17 Americans die while waiting for an organ transplant. Opt-out organ donation policies, which enroll everyone into post-mortem donation programs by default unless people choose to opt out, have been touted as ...

New Hampshire man resumes dialysis after record 271 days living with a pig kidney

A New Hampshire man is resuming dialysis after living with a gene-edited pig kidney for a record 271 days, doctors said Monday. His experience is helping researchers in their quest for animal-to-human transplants.

Liver transplantation utilizing grafts donated after euthanasia is feasible, study suggests

Organ donation following medical assistance in dying (MAiD), also known as euthanasia, is a relatively new practice both in North America and worldwide. A first comparison of liver transplantation using organs donated after ...

A 'bird's eye view' of how human brains operate

A new study provides the best evidence to date that the connection patterns between various parts of the human brain can tell scientists the specialized functions of each region.

Researchers decipher a mechanism that determines the complexity of the glucocorticoid receptor

Deciphering how the GR forms oligomers—through the binding of several subunits—opens a crucial avenue for developing more selective drugs. These new drugs could modulate this association and thus minimize serious adverse ...

Recommended News For You

Orca-T Approved to Prevent GVHD After Stem Cell Transplant for Blood Cancers

The Early Progression of Prostate Cancer Is Not Stopped by Metformin.

Toward rapid and comprehensive genetic diagnosis of pediatric cancer through adaptive sequencing

Low-Dose Radiation Provides Almost Perfect Control Over Slow-Growing Lymphoma.

Global warming could be driving up women's cancer risk, find researchers

Enhanced CAR T cell therapy offers new strategy for lymphoma

Urinary tract cancer prediction models with high sensitivity and specificity

Recommended Articles For You

Exploring The Science Of Hematopoietic Stem Cell Transplantation: What You Need To Know 

Revolutionizing Thyroid Cancer: Advances in Molecular Genetics and Personalized Treatment Approaches 

Uncovering Breast Cancer: The Power of Early Stage Ultrasound 

Rehabilitation of Hand Dexterity Following Hematologic Treatment-Associated Deconditioning 

Whats more on Hidoc Dr.

Medical Updates
KOL Videos
Surveys
Events

Daily news to keep you up to date

Gain valuable insights with our in-depth KOL Video discussions

Participate and win cash vouchers

Get updates on the latest events happening around the world
Featured News
Featured Articles
Featured Events
Featured KOL Videos

1.

Short Shrift in Cancer Funding; Bypassing Familiar for Distant; Testing for BRCA.

2.

Pre-operative evaluation of ovarian cancer patients using DWI-MRI is helpful.

3.

Rural colon cancer patients face higher risks, but minimally invasive surgery could narrow gap

4.

Novel topical fluorescent imaging technique rapidly and safely detects basal cell carcinoma

5.

Potential new therapy for childhood brain cancer could heal treatment-resistant tumors

1.

What is Hemorrhagic Cystitis and How to Manage its Symptoms

2.

How Digital Innovation and AI-Powered Case Studies are Revolutionizing Oncology Education?

3.

Blood Donation Sustainability Through Behavioral Science

4.

Emerging Therapies and Technologies Reshaping Oncology: Innovations and Impact in 2025

5.

Essential Developments in Oncology for Healthcare Excellence

1.

Asian Symposium on Advancement in Hematology and Oncology (ASAHO)

2.

International Cancer Conference

3.

Asian Symposium on Advancement in Hematology and Oncology (ASAHO)

4.

Asian Symposium on Advancement in Hematology and Oncology

5.

Asian Symposium on Advancement in Hematology and Oncology

1.

Targeting Oncologic Drivers with Dacomitinib: A New Approach to Lung Cancer Treatment

2.

Navigating the Complexities of Ph Negative ALL - Part XVI

3.

Molecular Contrast: EGFR Axon 19 vs. Exon 21 Mutations - Part VI

4.

Molecular Contrast: EGFR Axon 19 vs. Exon 21 Mutations - Part V

5.

Molecular Contrast: EGFR Axon 19 vs. Exon 21 Mutations - Part VII

Fastest Growing Medical Platform for Doctors

Address :
Hidoc Dr. Inc. | Delaware C Corp | 1309 Coffeen Ave. Suite 1200, Sheridan WY, 82801

Phone :
+1-415-463-3094

Email :
anishagadia@hidoc.co

Quick Links

Drug DatabaseDrug InteractionDiseases Database
KOL VideosKnowledge HubQuizzes
Medical UpdatesEventsAbout Us

© Copyright 2026 Hidoc Dr. Inc.

Terms & Conditions - LLP | Inc. | Privacy Policy - LLP | Inc. | Account Deactivation
Home
Profile
Login
bot