The world's first mRNA vaccine against a deadly disease

Published Date: 15 Mar 2023

A world first: A research team from Tel Aviv University and the Israel Institute of Biology has developed an anti-mRNA drug that is 100% effective against a single type of virus.

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Exercise and Cancer Survival; COVID Vaccine and Immune Checkpoint Inhibitors

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BPAP Intervention Flops in Asthma Study

Goal of decreasing the duration of beta-agonist therapy in the ED showed no significant effect

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STAREE trial will give its verdict on primary prevention statins in people ages 70 and up

Radio Silence on Mitch McConnell's Health Persists

84-year-old senator hasn't been seen in public since his hospitalization nearly 3 months ago

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The danger may be in the dosing, not in the drug itself

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Tozorakimab Cuts COPD Mucus Plugging, With George Washko, MD

Tozorakimab Cuts COPD Mucus Plugging, With George Washko, MD

Chronic Proton Pump Inhibitor Use Linked to More Asthma Exacerbations

Chronic Proton Pump Inhibitor Use Linked to More Asthma Exacerbations

FDA Approves Autoinjector for Self-Administered Zilucoplan in Generalized Myasthenia Gravis Marco Meglio

Adults with generalized myasthenia gravis who are anti-acetylcholine receptor antibody positive now have a second self-administration option for the complement inhibitor zilucoplan.

Levacetylleucine Shows Sustained Benefit at 3 Years in Niemann-Pick Disease Marco Meglio

Three-year extension data from the phase 3 IB1001-301 trial show levacetylleucine slowed disease progression in both adults and children with Niemann-Pick disease type C.

Recognizing Familial Chylomicronemia Syndrome in the APOC3 Era

Recognizing Familial Chylomicronemia Syndrome in the APOC3 Era

Todays Updates

Verekitug's Quarterly Dosing Cuts Asthma Burden, With Michael Wechsler, MD Michael Wechsler, MD, MSc

Wechsler discusses why less frequent dosing matters to patients with severe asthma, plus VALIANT's safety profile and what's next for the field.

Tozorakimab Cuts COPD Mucus Plugging, With George Washko, MD

Tozorakimab Cuts COPD Mucus Plugging, With George Washko, MD

Chronic Proton Pump Inhibitor Use Linked to More Asthma Exacerbations

Chronic Proton Pump Inhibitor Use Linked to More Asthma Exacerbations

FDA Approves Autoinjector for Self-Administered Zilucoplan in Generalized Myasthenia Gravis Marco Meglio

Adults with generalized myasthenia gravis who are anti-acetylcholine receptor antibody positive now have a second self-administration option for the complement inhibitor zilucoplan.

Levacetylleucine Shows Sustained Benefit at 3 Years in Niemann-Pick Disease Marco Meglio

Three-year extension data from the phase 3 IB1001-301 trial show levacetylleucine slowed disease progression in both adults and children with Niemann-Pick disease type C.

Recognizing Familial Chylomicronemia Syndrome in the APOC3 Era

Recognizing Familial Chylomicronemia Syndrome in the APOC3 Era

Latest News

— GI and respiratory symptoms at presentation both flagged in observational study

— Also in TTHealthWatch: colonoscopy after polyp removal

Goal of decreasing the duration of beta-agonist therapy in the ED showed no significant effect

STAREE trial will give its verdict on primary prevention statins in people ages 70 and up

84-year-old senator hasn't been seen in public since his hospitalization nearly 3 months ago

The danger may be in the dosing, not in the drug itself

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Discordant Tissue Findings in Suspected HLH

Hemophagocytic lymphohistiocytosis is a hyperinflammatory syndrome characterized by an exaggerated immune response to a triggering stimulus.

What Extreme Athletes Teach Us About Sleep Deprivation

What can a 1000-mile race teach MDs about sleep? Dr Alison Kole shares sleep deprivation insights from ultramarathon racing and gives practical tips for exhausted patients.

Omalizumab May Ease Inflammation in Chronic Urticaria

In patients with antihistamine-resistant chronic spontaneous urticaria, omalizumab treatment is linked to clinical improvement and reduced systemic inflammatory markers and D-dimer levels.

Pediatric Lung Transplantation Enters a New Era

New CFTR modulators are reshaping pediatric lung transplantation, forcing clinicians to rethink when children should be referred and listed.

CVS Health's Aetna to Streamline Cancer Treatment Approvals

CVS Health's Aetna health insurance unit will cut back next year on the preapprovals it requires for treatment ⁠for cancer patients to only one medical prior authorization...

Diphtheria Debate Exposes Health Misinformation

A diphtheria death in Sicily has reignited debate over vaccines, migration, and how political spin can distort public health facts.

Azithromycin Use Cuts Cesarean Infections

Azithromycin has been shown to lower the risk for postoperative infection during cesarean deliveries when added to more standard prophylactics such as cefazolin.

Methotrexate for IBD: How Do GIs Use It?

A new study offers the most comprehensive real-world look yet at methotrexate use in treating IBD in everyday practice.

AI Digital Twins Get Better and Better: Cancer in Crosshairs

Digital twins allow doctors to simulate treatment to see what will work best — and the tech has made real strides in cardiology. Oncology remains the bigger challenge.

S1P Modulators: 5 Agents, One Safety Playbook

Five S1P modulators now span neurology and GI. Bruce Cree, MD, PhD, and others weigh in on why selectivity differences are no longer academic.

As-Needed Allergic Rhinitis Meds Comparable to Daily Use

Patients with allergic rhinitis who use medication as needed can achieve symptom control and treatment satisfaction comparable to those achieved by patients who use them daily.

Host-Directed Therapies and Phages in Lung Care

Host-directed and phage therapies are emerging as alternatives to antibiotics in managing lung infections in a worsening antimicrobial resistance crisis.

Mild Brain Injury Frequently Missed in the ED

Only 21% of adults with closed head injury have mTBI diagnosed or clinically suspected in the ED, despite 41% meeting diagnostic criteria, with missed diagnoses most common among middle-aged adults.

D10 Matches D50 for Hypoglycemia, Shows Lower Rebound Risk

A lower-concentration dextrose solution matches the standard treatment for hypoglycemia in the emergency department but carries a lower risk for rebound hypoglycemia.

A Rare Hearing Implant Bypasses Damaged Nerves

When cochlear implants failed, doctors turned to a brainstem auditory implant to restore sound awareness in a patient with profound deafness.

Two-Midnight Rule: Key Strategies for Observation Patients

The Two-Midnight Rule has created important clinical and operational strategies for hospitals.

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