The world's first mRNA vaccine against a deadly disease

Published Date: 15 Mar 2023

A world first: A research team from Tel Aviv University and the Israel Institute of Biology has developed an anti-mRNA drug that is 100% effective against a single type of virus.

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Tirzepatide-Associated Ketoacidosis in One Woman

A single dose of tirzepatide was followed by persistent vomiting and severe high-anion-gap acidosis in a nondiabetic woman, highlighting a rare safety concern.

Chronic Eosinophilic Pneumonia in Man With Persistent Cough

A man with chronic cough and migratory pulmonary infiltrates is diagnosed with chronic eosinophilic pneumonia after infection, tuberculosis, and other mimics are excluded.

1 in 5 Patients With Bacteremia Have Skin Involvement

Skin involvement is common in neutropenic patients with a Pseudomonas aeruginosa bloodstream infection, a study suggests.

Cancer Risk Low, Similar Across IBD Advanced Therapy Classes

Patients with IBD face similar risk for cancer whether treated with TNF antagonists, vedolizumab, anti-interleukins, or JAK inhibitors, with overall incidence remaining low across all therapy classes.

e-Cigarettes May Increase Risk for RA or SLE

Current e-cigarette users face a higher risk of developing incident rheumatoid arthritis or systemic lupus erythematosus than nonusers, a study finds.

MMR Deficiency Tied to Better Survival in Gastric Cancer

Patients with mismatch repair-deficient oesophagogastric adenocarcinoma treated with perioperative chemotherapy show significantly improved survival outcomes.

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FDA Approves Camizestrant for ESR1-Mutated Breast Cancer

The accelerated approval enables an endocrine therapy switch when the ESR1 resistance mutation is detected, rather than waiting for evidence of disease progression.

Todays Updates

FDA Approves Camizestrant for ESR1-Mutated Breast Cancer

The accelerated approval enables an endocrine therapy switch when the ESR1 resistance mutation is detected, rather than waiting for evidence of disease progression.

Latest News

A single dose of tirzepatide was followed by persistent vomiting and severe high-anion-gap acidosis in a nondiabetic woman, highlighting a rare safety concern.

A man with chronic cough and migratory pulmonary infiltrates is diagnosed with chronic eosinophilic pneumonia after infection, tuberculosis, and other mimics are excluded.

Skin involvement is common in neutropenic patients with a Pseudomonas aeruginosa bloodstream infection, a study suggests.

Patients with IBD face similar risk for cancer whether treated with TNF antagonists, vedolizumab, anti-interleukins, or JAK inhibitors, with overall incidence remaining low across all therapy classes.

Current e-cigarette users face a higher risk of developing incident rheumatoid arthritis or systemic lupus erythematosus than nonusers, a study finds.

Patients with mismatch repair-deficient oesophagogastric adenocarcinoma treated with perioperative chemotherapy show significantly improved survival outcomes.

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Skin Deep: Could Clues Reveal Underlying Disease Early?

From liver disease to malignancy, characteristic skin findings can prompt a broader evaluation and help physicians consider systemic conditions during routine examinations.

Novartis MS Pill Beats Older Drug in Trials, Boosts Pipeline Hopes

(Corrects paragraph 12 to say remi is approved to treat only one skin condition, not two)

Teva's Immune Disorder Drug Meets Main Goal in Mid-stage Trial

Israeli drugmaker Teva Pharmaceutical Industries, said on Wednesday its experimental drug helped prevent gluten-related intestinal damage in ⁠adults with celiac disease,...

Maternal HIV Treatment May Aid Child Viral Load Suppression

Children living with HIV whose mothers receive antiretroviral therapy or achieve viral load suppression are more likely to receive antiretroviral therapy themselves.

Lipid-Lowering Drugs Tied to Worse Venom Anaphylaxis

Patients receiving lipid-lowering medications face roughly double the odds of severe anaphylaxis after Hymenoptera stings compared with those not taking these medications.

Controversial Drug Suspended Due to Trial Irregularities

MHRA suspends new use of avacopan after concluding pivotal trial data can no longer be trusted, despite real-world evidence of efficacy.

Exclusive-US Refusals Of Crucial Newborn Vitamin Spike, Raising Risk Of Dangerous Bleeding

The percentage of parents and caregivers in the United States refusing a standard vitamin K shot for infants at birth has accelerated sharply this year, an exclusive data...

How Biologics Have Changed Atopic Dermatitis Treatment

Experts highlight the positive impact biologic treatments have had on the care of patients with atopic dermatitis, with even more promising agents in development.

Digital Tool May Help Optimise Allergic Rhinitis Care

A digital decision-support tool aligned with allergic rhinitis guidelines may aid in identifying opportunities to adjust allergic rhinitis treatment among primary care patients.

Necrotic Eschar on the Back in a Preterm Neonate

A 5-day-old girl born at 23 weeks’ gestation was evaluated in the neonatal intensive care unit for a skin lesion on the back. What’s the diagnosis?

Unexplained Symptoms? Consider Cat-Associated Infections

A careful pet history can point to infections ranging from Bartonella and Pasteurella to toxoplasmosis, ringworm, and, rarely, rabies.

Kidney Donors Maintain High Self-Esteem Post-Donation

Tracking living kidney donors for 5 years reveals that nearly all maintain normal-to-high self-esteem after donation, with those having lower baseline self-esteem experiencing modest improvements.

Doctors Sue Over Federal Dietary Guidelines

A federal lawsuit challenges the 2025-2030 Dietary Guidelines, alleging that conflicts of interest and a secretive process violated federal law.

Inhaled Corticosteroids Safe for Pregnancy but Underused

Experts say clinicians should reassure pregnant patients that inhaled corticosteroids are safe and emphasize the risks of stopping treatment.

Alumis Eyes Late-stage Lupus Study Despite Trial Miss

Alumis said on Tuesday it plans to advance its experimental drug for a type of immunity-related condition in a ⁠smaller subset of patients, even after the treatment failed...

Cold Urticaria Often Missed by Standard Testing

About 1 in 3 patients with convincing cold-induced symptoms test negative on the standard cold stimulation test and show a clinical profile distinct from those who test positive, a study shows.