EMA Turns Down 3 Therapies Across Oncology, Transplantation

Published Date: 30 Jun 2026

Tacquell, Yartemlea, and Xervyteg failed to secure positive CHMP recommendations after EMA identified major concerns with efficacy, safety, and data interpretability.

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The first oral PCSK9 inhibitor, another study finding safe MRI scanning in patients with nonconditional CIEDs, the PFA-SHAM trial, and the curious case of orthopedic injuries in cardiology are the topics John Mandrola, MD, discusses in this week’s podcast.

A compression device worn around the abdomen during colonoscopy shortens procedure time and reduces discomfort.

Catheter placement after ureteroscopic lithotripsy appears to be safe and is linked to a lower incidence of pain and urinary urgency 1 day after surgery.

Neurologist Christoph Diener summarizes what randomized studies in the last 4-5 years have taught us about the management of acute ischemic stroke.

Skin prick tests and specific IgE levels are moderately useful for predicting oral food challenge outcomes in patients with cow’s milk or hen’s egg allergy.

Review finds limited evidence supporting most IVF add-ons, reinforcing calls for stronger trials and transparent counseling before routine use.

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