Neoadjuvant immunotherapy improves outcomes in high-risk melanoma patients.

Published Date: 02 Mar 2023

High-risk melanoma patients who received the drug pembrolizumab before or after surgery to remove the cancer had a higher risk of developing melanoma than those who did not have a similar condition that eliminated cancer cells.

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Primary Care on the Front Lines of Mental Health Care

With a mental health care provider shortage and many patients’ seeking mental health support, primary care doctors have stepped up to the front lines.

Strategies for Latent TB Infection Screening and Care

While tuberculosis spread is not significant nationally, lack of awareness of the latent form of the condition raises legitimate concerns for potential future infections.

Residency Training May Formalize Digital Competencies

Medical residents report limited structured training in AI and digital health despite increasing clinical relevance.

S Korea Bans Syringe Stockpiling to Prevent Supply Disruptions

South Korea will ⁠ban stockpiling medical syringes and needles ⁠to prevent supply disruptions at ⁠hospitals starting on ‌Tuesday.

Teleneurology Bests On-Site Rounds for Postacute Stroke

In a head-to-head comparison of telemedicine and on-site care in postacute stroke rounds, teleneurology outperforms in-person consultations for guideline-supported care.

Feeding a Need: Hospitals Addressing Food Insecurity

Food insecurity is a growing problem, linked with higher rates of hospitalization and chronic illness. With 1 in 7 children affected, pediatric hospitals are taking action.

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Early Tislelizumab May Boost PFS in Esophageal Cancer

For patients with locally advanced esophageal cancer, front-loading immunotherapy with induction chemo and chemoradiotherapy, without maintenance immunotherapy, may improve outcomes.

ctDNA Predicts Relapse in Locally Advanced Cervical Cancer

Posttreatment ctDNA positivity correlates with worse relapse-free survival and earlier recurrence in patients with locally advanced cervical cancer, real-world data show.

GLP-1 RAs May Lower Hysterectomy Risk in Endometrial Cancer

There’s now a hint that GLP-1 receptor agonists might prevent hysterectomies in endometrial intraepithelial neoplasia/early-stage endometrial cancer, but prospective trials are needed to confirm it.

Todays Updates

Early Tislelizumab May Boost PFS in Esophageal Cancer

For patients with locally advanced esophageal cancer, front-loading immunotherapy with induction chemo and chemoradiotherapy, without maintenance immunotherapy, may improve outcomes.

ctDNA Predicts Relapse in Locally Advanced Cervical Cancer

Posttreatment ctDNA positivity correlates with worse relapse-free survival and earlier recurrence in patients with locally advanced cervical cancer, real-world data show.

GLP-1 RAs May Lower Hysterectomy Risk in Endometrial Cancer

There’s now a hint that GLP-1 receptor agonists might prevent hysterectomies in endometrial intraepithelial neoplasia/early-stage endometrial cancer, but prospective trials are needed to confirm it.

Latest News

With a mental health care provider shortage and many patients’ seeking mental health support, primary care doctors have stepped up to the front lines.

While tuberculosis spread is not significant nationally, lack of awareness of the latent form of the condition raises legitimate concerns for potential future infections.

Medical residents report limited structured training in AI and digital health despite increasing clinical relevance.

South Korea will ⁠ban stockpiling medical syringes and needles ⁠to prevent supply disruptions at ⁠hospitals starting on ‌Tuesday.

In a head-to-head comparison of telemedicine and on-site care in postacute stroke rounds, teleneurology outperforms in-person consultations for guideline-supported care.

Food insecurity is a growing problem, linked with higher rates of hospitalization and chronic illness. With 1 in 7 children affected, pediatric hospitals are taking action.

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FDA Approves Higher Dose Of Genetic Disorder Drug for SMA

The U.S. Food and Drug Administration has approved a higher dose of Biogen's spinal muscular atrophy ⁠drug Spinraza, the company said on Monday, after rejecting it last...

Separate Hiring for Abortion Doctors Barred in Sicily

Italy's Constitutional Court bars Sicily from advertising jobs reserved for health workers willing to ⁠perform abortions, but it can find alternatives to safeguard access.

Real-Time Antimicrobial Stewardship May Aid Bacteremia Care

A real-time antimicrobial stewardship intervention may increase early switches from intravenous to oral antibiotics for nonstaphylococcal bloodstream infections, without changing clinical outcomes.

Retaining APPs: Why One APP Won’t Leave Rheumatology

Clear expectations, mutual respect with physicians, and compensation models all play important roles in retaining advanced practice providers, a physician assistant says.

Pneumonia Tied to Noncommunicable Disease Risk in Adults

Hospitalization for community-acquired pneumonia is linked to an increased risk of developing multiple chronic noncommunicable diseases over 5 years in adults.

Is ‘Spring Fatigue’ Real? Sleep Study Questions It

In a nine-wave online survey of 418 adults over 18 months, researchers find fatigue levels do not fluctuate seasonally — only everyday activity fatigue falls as days lengthen.

Telemedicine Matches Clinic Visits in IIH Care

Remote consults using optical coherence tomography data show high agreement with traditional clinic evaluations for the management of patients with idiopathic intracranial hypertension.

When Medications May Contribute to Cognitive Decline

Medication-related cognitive impairment is common, mimics neurodegenerative disease, increases with polypharmacy, and may be prevented with regular cognitive assessment monitoring.

Access to Mental Health Support ‘Uneven’ for Young Canadians

The need for mental health support services is high in Canada, especially among youth, but many are unable to access the care they need in a timely manner.

Pope Leo Calls Universal Healthcare a 'Moral Imperative'

Pope Leo has made a plea for countries ⁠to offer their citizens universal healthcare, calling it a "moral imperative" that people have access to ⁠the health services they need.

Will the UK Lose Senior Doctors Earlier Than EU Peers?

Findings from a Medscape survey suggest German and French doctors plan to work longer than their British counterparts — and it’s not just a lifestyle choice.

Human Milk Tied to Fewer Respiratory Admissions in Preemies

Among infants born very preterm, human milk feeding at hospital discharge is associated with fewer respiratory hospital admissions during their first 18 months than exclusive formula feeding.

Depression Predicts Disability Progression in Progressive MS

Depression screening predicts subsequent disability progression in people with primary progressive multiple sclerosis.

World’s Best Hospitals Ranking Puts Mayo Back at No. 1

A new global hospital ranking spanning 32 countries places Mayo Clinic first and highlights strong performances from hospitals in Germany, Switzerland, and Austria.

How Babies Process Pain — and Sugar’s Role in Relieving It

Mounting evidence backs sucrose as an analgesic for newborns — yet their experience of pain remains mysterious.

Environmental Pollution From Pharmaceuticals Raises Concern

Pharmaceutical residues increasingly enter ecosystems across the drug life cycle, prompting calls for coordinated global action grounded in One Health principles.

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