Neoadjuvant immunotherapy improves outcomes in high-risk melanoma patients.

Published Date: 02 Mar 2023

High-risk melanoma patients who received the drug pembrolizumab before or after surgery to remove the cancer had a higher risk of developing melanoma than those who did not have a similar condition that eliminated cancer cells.

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ASTRO: American Society for Radiation Oncology

Todays Updates

ASTRO: American Society for Radiation Oncology

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Nearly 3 in 10 Italians older than 65 years take more than 10 medications, highlighting why deprescribing is gaining attention as a strategy to improve care.

Respiratory experts disagree over initiating upfront dual therapy vs sequential escalation as next-generation antifibrotics emerge for pulmonary fibrosis.

A ketogenic diet paired with weight loss improves liver health more than a Mediterranean or very low-fat diet with similar weight loss in people with metabolically unhealthy obesity.

Extremely preterm birth in infants with bronchopulmonary dysplasia is associated with similar post-discharge respiratory visits and lower medication use compared with slightly later preterm birth.

Adding telitacicept to standard therapy can improve renal response rates in patients with proliferative lupus nephritis while allowing for reduced steroid use.

The walkouts are the next stage of the doctors’ effort to improve what they call long hours and poor working conditions.

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Rheumatologists Seek Changes to Looming Medicaid Work Rules

Groups such as the ACR object to a CMS ‘frailty-exemption’ rule intended to make clinicians try to judge patients’ ability to work, noting among their objections a lack of adequate tools for this task.

Can Sexual Experience Reshape the Brain?

New research is exploring whether sexual experience may shape brain circuits linked to reward, learning, and mood — but the human evidence remains early.

Somatic Mutations Shape Systemic Autoinflammatory Disease

Acquired somatic variants may drive over 20% of systemic autoinflammatory disease diagnoses, with VEXAS syndrome and cryopyrin-associated periodic syndromes representing the majority of cases.

Sonographer Shortage Is Affecting Expectant Women’s Health

A sonographer shortage confronts expectant women in Ontario with long commutes for routine ultrasounds.

How Clinicians Can Improve STI Conversations

A Spanish sexologist says the key to better STI detection may be simpler than it seems: create a safe, nonjudgmental space and ask directly.

Ultrasound Expands Options for Chest Lesion Biopsy

A radiation-sparing procedure shows a safe and effective diagnostic potential.

Irish Health Service Operator Fined for Storing Data in Disused Bathroom, Turf Shed

Ireland's health service operator was fined a record amount for an Irish public body by the country's data regulator ⁠for storing medical records in "profound disarray" in...

How to Differentiate the Major Subtypes of ILD

The definitions of interstitial lung disease subtypes have undergone major revisions, encompassing clinical, radiologic, and histologic findings, as well as a few new categories.

Long-Term Primary Care Saves Lives — and Is Hard to Achieve

New research quantifies the benefits of long-term patient relationships. How can you build them in a system that prioritizes high-volume access?

UnitedHealthcare to Drop Prior Authorization Requirements for Range Of Conditions From Oct. 1

UnitedHealth's insurance unit said on Tuesday that a broad range of conditions will no ⁠longer need prior approval, effective October 1, as it aims to eliminate prior...

Size Matters for Chest Tubes

New data show similar outcomes with large-bore and small-bore chest tubes in patients with pneumothoraces.

Rilzabrutinib May Be Promising in IgG4-Related Disease

Rilzabrutinib treatment is associated with a reduction in disease activity in patients with IgG4-related disease and enables most patients to discontinue glucocorticoids without experiencing flares.

What to Know About ‘Musculoskeletal Syndrome of Menopause’

Is new joint pain in perimenopause simple arthralgia or underlying inflammatory arthritis? Learn key diagnostic steps, seronegative RA risks, and hormone replacement therapy insights.

Strategies to Optimize Sepsis Outcomes

Multi-society position paper presents strategies for improvement at the hospital and systems level.

MRI Pattern May Forecast MCI to Dementia Timeline

An MRI-defined pattern of cortical atrophy may help identify patients with early-onset Alzheimer’s disease at risk for more rapid progression from MCI to dementia.

At-Home Lecanemab: What Does It Mean for Alzheimer’s Care?

At-home subcutaneous lecanemab may ease the burden of frequent infusions, but clinicians still face key questions about patient selection, training, ARIA monitoring, adherence, and access.

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