Neoadjuvant immunotherapy improves outcomes in high-risk melanoma patients.

Published Date: 02 Mar 2023

High-risk melanoma patients who received the drug pembrolizumab before or after surgery to remove the cancer had a higher risk of developing melanoma than those who did not have a similar condition that eliminated cancer cells.

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Faricimab may stabilize vision, reduce retinal fluid and thickness, and cut treatment burden in difficult-to-treat cases of wet age-related macular degeneration.

Waiting for prior authorization of drugs affects a small portion of patients with age-related macular degeneration, resulting in vision loss.

Sri Lanka's public health services and hospitals are battling the worst outbreak of mosquito-borne dengue in nearly a decade, and turning to the island nation's armed...

In patients with mild immune-related pneumonitis, a shorter 3-week corticosteroid regimen does not meet noninferiority compared with the standard 6-week taper.

Cefazolin is noninferior to antistaphylococcal penicillins for methicillin-susceptible Staphylococcus aureus bacteremia and is associated with a lower risk for acute kidney injury.

Confirmed case count across 34 states is five times the number reported last summer, the CDC says.

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RSV Preventive Strategies Tied to Fewer Bronchiolitis Cases

Administration of nirsevimab and RSV vaccination in pregnant women are tied to significant reductions in hospitalized days and oxygen requirements among infants with bronchiolitis.

Light Activity Pays Off for COPD Survival

New data show that patients need not exercise intensely to improve outcomes.

Initial Prescription Duration May Shape Benzodiazepine Use

Longer durations of initial prescriptions are associated with prolonged use of benzodiazepines compared with durations of 7 days or less, a large cohort study shows.

Alcohol’s Health Myth Is Over. How to Tell Patients

The science on alcohol has changed dramatically. Here’s how experts say physicians can explain why older advice no longer holds up — and counsel patients without judgment.

US House Committee Opens Investigation Into Merck, AbbVie China Drug Trials

The chair of the U.S. House Select Committee on China opened national security investigations into whether five drugmakers including Merck and AbbVie have been involved in...

Bepirovirsen Achieves Functional Cure in HBV Phase 3 Trial

In patients with chronic hepatitis B infection, bepirovirsen achieves significantly higher rates of functional cure than placebo after discontinuation of nucleoside or nucleotide analog therapy.

Retina Care Visits Reveal High BP in Adults With Diabetes

Many adults with diabetes have uncontrolled or previously undiagnosed high blood pressure during their routine visits to retina clinics, prompting referrals and urgent follow-up, a study finds.

Venezuela Health System Strained After Earthquakes, WHO Says

Venezuela's healthcare system is under significant strain, ⁠the World Health Organization said on Tuesday, with some hospitals damaged and ⁠others missing staff after deadly...

Evidence for tVNS Stronger for Anxiety Than Cognition

Transcutaneous vagus nerve stimulation was associated with reduced anxiety severity but showed no significant benefit for working memory or inhibitory control in healthy adults.

Delirium After Surgery Linked to Lasting Loss of Cognition

Delirium after surgery is associated with lasting decline in cognition in older adults, and rehospitalizations may not explain this association.

RSV More Common Than hMPV in Adults With Chronic Illness

In adults with chronic underlying health conditions, respiratory syncytial virus is detected more often than human metapneumovirus, especially in inpatient settings, a meta-analysis finds.

No Gender Disparity in Deaths After Anaphylaxis

Hospital stay, hospital charges, and other secondary outcomes also were similar between male and female patients.

When AI Makes the Call, Doctors May Take the Blame

For all its promise and computational power, will AI in clinical medicine overcome physicians’ concerns?

New Artificial Neurons Cause Living Brain Cells to Fire

An array of artificial neurons printed on a flexible wafer produce spiking waveforms closely matching biological action — and drive living mouse brain cells to fire.

China Outpacing Europe in Drug Innovation, Pfizer Executive

China has pulled ahead of Europe in pharmaceutical innovation and drug development, a senior Pfizer executive ⁠said on Tuesday.

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Tests show greatest value when used alongside imaging.

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