Neoadjuvant immunotherapy improves outcomes in high-risk melanoma patients.

Published Date: 02 Mar 2023

High-risk melanoma patients who received the drug pembrolizumab before or after surgery to remove the cancer had a higher risk of developing melanoma than those who did not have a similar condition that eliminated cancer cells.

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Immunotherapy Remains Little Used in Head and Neck Cancer

Immune checkpoint inhibitors have been FDA-approved for head and neck cancer for a decade, but their use has only marginally increased among patients younger than 65.

EVP Beats Cisplatin for Resectable MIBC

As the first chemotherapy-free regimen to beat gemcitabine/cisplatin, perioperative enfortumab vedotin plus pembrolizumab could shift muscle-invasive bladder cancer care — but questions remain.

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Belzutifan plus lenvatinib significantly improves outcomes vs single agent cabozantinib in patients with advanced RCC who progressed after anti-PD-(L)1 therapy, new data show.

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The deadline is 9 PM ET Wednesday for fourth-year students to submit their residency preference lists.

A dozen public health experts are arriving in South Carolina to help the state contain the largest U.S. measles outbreak in more than 30 years, but they're not coming from...

Individuals receiving maximum oxytocin doses have elevated risk for cesarean delivery and postpartum hemorrhage, but the risks are attenuated in those with elevated BMI.

Med students have until March 4 to finalize their Match lists. There is a lot to consider before then.

As trust in healthcare erodes and disinformation thrives on social media, a small but determined group of physicians wants to win.

FDA Approves New Narcan Packaging, Aiming to Boost Carry Rates

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Icotrokinra beneficial for adults, teens with plaque psoriasis

For adults and adolescents with moderate-to-severe plaque psoriasis, selective blockade of the interleukin-23 receptor with the targeted oral peptide icotrokinra yields a significantly higher incidence of skin clearance at ...

How controlling sunburn-triggered inflammation may prevent skin cancer

Sunlight is vital for human health as it helps the body produce essential nutrients, such as vitamin D. However, too much sun exposure can significantly increase the risk of skin cancer.

Cellular protein FGD3 boosts breast cancer chemotherapy and immunotherapy, study finds

A naturally-occurring protein that tends to be expressed at higher levels in breast cancer cells boosts the effectiveness of some anticancer agents, including doxorubicin, one of the most widely used chemotherapies, and a ...

Gut bacterium may sabotage liver cancer immunotherapy, study suggests

A research team led by the Department of Clinical Oncology, Center of Cancer Medicine, School of Clinical Medicine, LKS Faculty of Medicine, the University of Hong Kong (HKUMed), has identified a critical factor contributing ...

Researchers try bold new approach in a race to better treat autoimmune diseases

Scientists are trying a revolutionary new approach to treat rheumatoid arthritis, multiple sclerosis, lupus and other devastating autoimmune diseases—by reprogramming patients' out-of-whack immune systems.

Immune reactions found behind human rejection of transplanted pig kidneys

Researchers have uncovered and then overcome an obstacle that has led to the failure of pioneering efforts in xenotransplantation, in which an animal kidney is transplanted into a human.

Common cold virus may unlock better COVID vaccine

Prior exposure to coronaviruses that cause ordinary colds can boost the immune system's ability to attack a vulnerable site on the COVID-19-causing coronavirus SARS-CoV-2, according to a study led by investigators at Weill ...

Global reviews call for urgent action on endometriosis in most world regions

Two reviews published in The Lancet Obstetrics, Gynecology & Women's Health reveal stark global inequities in how endometriosis is recognized, treated, and prioritized in national health systems.

Mental and physical coaching before surgery prepares immune system and reduces complications, trial finds

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Rapid growth of radiopharmaceutical therapy highlights need for expertise

The Society of Nuclear Medicine and Molecular Imaging (SNMMI) has released a position paper outlining the education, training, and experience needed to ensure the safe and effective delivery of radiopharmaceutical therapy ...

Flu vaccine performance varies by age, study reveals

New research comparing four different flu vaccines found that the ability of the vaccines to activate cells of the immune system that help to protect against infection varied greatly depending on the vaccine type and age ...

Study tracking how tumor microenvironment develops signals opportunity for early detection, risk prediction

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Researchers aim to disrupt breast cancer line of communication and prevent spread

Cancer Center at Illinois (CCIL) Program Leader Erik Nelson's lab made an important discovery about the relationship between cholesterol and breast cancer progression with crucial implications for breast cancer therapeutics.

Study reveals why some myeloma patients stay cancer-free for years after CAR T therapy

A new study from the Icahn School of Medicine at Mount Sinai helps explain why some people with multiple myeloma, a type of blood cancer, stay in remission for many years after receiving CAR T cell therapy, while others see ...

T cell therapies show long-term HPV gains

Researchers from Rutgers Cancer Institute, New Jersey's only National Cancer Institute (NCI)—designated Comprehensive Cancer Center, and RWJBarnabas Health, along with colleagues from the National Cancer Institute, a center ...

FDA grants fast track designation to drug combo for colorectal cancer

The U.S. Food and Drug Administration has granted Fast Track Designation to a new drug combination for metastatic colorectal cancer, following encouraging results from a clinical trial led in part by the University of Oklahoma ...

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