Neoadjuvant immunotherapy improves outcomes in high-risk melanoma patients.

Published Date: 02 Mar 2023

High-risk melanoma patients who received the drug pembrolizumab before or after surgery to remove the cancer had a higher risk of developing melanoma than those who did not have a similar condition that eliminated cancer cells.

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Supercharging immune cells to fight drug resistant bowel cancer

Scientists at University College London have engineered a rare type of immune cell to kill slow-growing bowel cancer cells that are resistant to current therapies, a breakthrough that could lead to new treatments in the future.

'Craters' on surface of melanoma cells mark tumor-killing hotspots, study reveals

New research published in Cell finds the existence of craters on the surface of melanoma cells that serve as immune hubs, becoming major sites for tumor killing. These craters could serve as good markers for immunotherapy ...

Crucial protein enables immune system memory

Researchers at the University of Missouri School of Medicine have recently found that a certain protein may have a large influence on how the immune system functions.

Cancer patients' thymic health is linked to their response to immunotherapy 

In cancer patients, the health of the thymus—a key part of the body's immune system—is associated with the outcomes these patients experience after immune checkpoint inhibitor treatment, according to an international ...

How bacteria in tumors drive treatment resistance in cancer

Researchers from The University of Texas MD Anderson Cancer Center have discovered a previously unknown mechanism that explains how bacteria can drive treatment resistance in patients with oral and colorectal cancer. The ...

Biomarker analysis reveals clues to long-term survival in glioblastoma patients treated with SurVaxM

Results of a study led by researchers at Roswell Park Comprehensive Cancer Center are shedding light on why some newly diagnosed glioblastoma patients survive longer than others after receiving standard treatment in conjunction ...

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Oral drug combination extends progression-free survival in advanced ER-positive breast cancer

Patients with estrogen-receptor-positive HER-2-negative advanced breast cancer showed significantly improved progression-free survival when treated with an oral combination regimen that includes giredestrant, a novel, next-generation ...

Todays Updates

Oral drug combination extends progression-free survival in advanced ER-positive breast cancer

Patients with estrogen-receptor-positive HER-2-negative advanced breast cancer showed significantly improved progression-free survival when treated with an oral combination regimen that includes giredestrant, a novel, next-generation ...

Latest News

Scientists at University College London have engineered a rare type of immune cell to kill slow-growing bowel cancer cells that are resistant to current therapies, a breakthrough that could lead to new treatments in the future.

New research published in Cell finds the existence of craters on the surface of melanoma cells that serve as immune hubs, becoming major sites for tumor killing. These craters could serve as good markers for immunotherapy ...

Researchers at the University of Missouri School of Medicine have recently found that a certain protein may have a large influence on how the immune system functions.

In cancer patients, the health of the thymus—a key part of the body's immune system—is associated with the outcomes these patients experience after immune checkpoint inhibitor treatment, according to an international ...

Researchers from The University of Texas MD Anderson Cancer Center have discovered a previously unknown mechanism that explains how bacteria can drive treatment resistance in patients with oral and colorectal cancer. The ...

Results of a study led by researchers at Roswell Park Comprehensive Cancer Center are shedding light on why some newly diagnosed glioblastoma patients survive longer than others after receiving standard treatment in conjunction ...

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Blood cancer: Scientists reprogram cancer cell death to trigger immune system

The aim of immunotherapy strategies is to leverage cells in the patient's own immune system to destroy tumor cells. Using a preclinical model, scientists from the Institut Pasteur and Inserm successfully stimulated an effective ...

FDA approves Zoryve for atopic dermatitis in young children

The U.S. Food and Drug Administration has approved the supplemental new drug application for Zoryve (roflumilast) cream 0.05% for the topical treatment of mild-to-moderate atopic dermatitis in children 2 to 5 years of age.

Study reveals a link between World Trade Center toxic exposures and lung cancer

The health risks from toxic exposures at Ground Zero of the 9/11 World Trade Center attacks are well documented, and diseases caused by those exposures continue to plague WTC responders as we approach 25 years since 9/11. ...

Certain dietary fatty acids can supercharge cancer-fighting immune cells

A research team at the LKS Faculty of Medicine of the University of Hong Kong (HKUMed) has discovered that certain dietary fatty acids can supercharge the human immune system's ability to fight cancer. The team found that ...

Seasonal allergies may increase suicide risk: New research

Seasonal allergies—triggered by pollen—appear to make deaths by suicide more likely. Our findings, published in the Journal of Health Economics, show that minor physical health conditions like mild seasonal allergies, ...

Breastfeeding for at least six months strengthens immunity in babies, study suggests

Breastfeeding until at least six months helps babies to fight off infections and reduces chronic inflammation, according to a new study. And better understanding the way specific nutrients in breast milk impact the immune ...

Engineered CAR-NK cells could evade immune rejection and target cancer more effectively

One of the newest weapons that scientists have developed against cancer is a type of engineered immune cell known as CAR-NK (natural killer) cells. Similar to CAR-T cells, these cells can be programmed to attack cancer cells.

Cancer researchers highlight role of nanomedicine in next-generation immunotherapies

Scientists at Virginia Tech's Fralin Biomedical Research Institute at VTC and their collaborators are exploring emerging trends in cancer immunotherapy with back-to-back review articles published in Nature Cancer and Trends ...

Repeated brain tumor sampling uncovers treatment response in patients with glioblastoma

A multi-institutional study from the Accelerating GBM Therapies Through Serial Biopsies TeamLab, led by investigators from the Mass General Brigham Cancer Institute, found that serially testing tumor samples can help detect ...

Novel immunotherapy combination destroys colorectal liver metastases

Advanced colon cancer is the leading cause of cancer-related death in young American men and the second highest worldwide. In the majority of these patients, as the cancer advances it metastasizes to the liver. Despite progress ...

Could reducing inflammation help combat fatigue in people with early-stage breast cancer?

New research reveals that inflammatory responses may play a role in different types of fatigue experienced by many people with cancer. The findings are published in Cancer.

From trips to treatments: How psychedelics could revolutionize anti-inflammatory medicine

Once synonymous with hippies and hallucinatory experiences, psychedelic drugs are now being explored for their medical potential. The stigma of that era resulted in research being suppressed by drug laws, yet with mental ...

What a respiratory system expert wants you to know about asthma

We all know that asthma impacts breathing. What may be less known is that the disease, which restricts our airways due to inflammatory responses, can be caused throughout our lifetime by a variety of things. It can be treated ...

Severe obesity causes lungs to age prematurely, study suggests

A research team has determined that severe obesity causes the lungs to age faster. The team was led by Prof. Dr. Veronika Lukacs-Kornek from the "ImmunoSensation2" Cluster of Excellence at the University of Bonn and the Institute ...

What is lupus, the condition Selena Gomez is diagnosed with?

Actress, singer and makeup mogul Selena Gomez has been candid about her experience of living with lupus. Since 2015, Gomez has documented on social media and in interviews the effect the condition has had on her health.

Easy-to-implement tools boost pediatricians' adherence to peanut allergy guidelines nearly 15-fold

A few easy-to-implement tools—a training video, electronic health record prompts and handouts for families—greatly increased how often pediatricians recommended early peanut introduction to infants, reports a new clinical ...

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