Neoadjuvant immunotherapy improves outcomes in high-risk melanoma patients.

Published Date: 02 Mar 2023

High-risk melanoma patients who received the drug pembrolizumab before or after surgery to remove the cancer had a higher risk of developing melanoma than those who did not have a similar condition that eliminated cancer cells.

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Culture findings were key in making the diagnosis

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Latest News

Bevacizumab is a cornerstone retina drug that has been used off-label for decades. Where the FDA-cleared branded version fits in may be a matter of cost and acceptance.

Healthcare workers are facing more violence and staff shortages, fueling hospital strikes as workers push for safer workplaces and enough staff to care for patients.

Thinning of specific retinal layers predicts cognitive worsening in patients with multiple sclerosis, even without disease relapses — suggesting the eye may reveal hidden neurodegeneration.

Higher nurse-led supportive care intensity is associated with a better quality of life and lower symptom burden in patients receiving palliative chemotherapy, a study reports.

A ‘living’ evidence review of bipolar disorder treatments has been transformed into a free, continuously updated online tool that helps clinicians and patients weigh efficacy, side effects, and individual preferences.

Citicoline added to dopaminergic therapy is safe and tied to higher odds of clinically meaningful improvement than placebo in motor function in Parkinson’s, a trial shows.

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Defining COPD Phenotypes With Advanced Imaging

Visual characteristics of lung disease are helping pulmonologists establish care plans and interventions.

Triple Therapy Reduces Antibiotic Use in Pediatric CF

A triple-combination therapy targeting the underlying defect in cystic fibrosis was associated with a dramatic reduction in antibiotic exposure among children and adolescents.

NHS Rehab Cuts Leaving Patients With ‘Avoidable Disability’

Recruitment freezes and lost rehab space are harming patient care, a CSP survey of 548 NHS physiotherapists finds.

ACARD Score Predicts Mortality in Status Epilepticus

A newly developed prognostic tool outperforms existing scoring systems in predicting short-term mortality risk following status epilepticus.

THC Safe, Effective for PTSD-Related Nightmares

Dronabinol, a medication containing THC, is linked to fewer nightmares at lower intensity compared to placebo in patients with post-traumatic stress disorder, new data show.

French Hospital Brings Phage Therapy Closer to Clinical Use

A first-in-world public authorization to manufacture GMP therapeutic phages could expand clinical trials, strengthen regulated access, and accelerate evidence-based treatment.

Self-Sampling Can Be Feasible for Respiratory Infections

A Swiss pilot study shows that self-sampling at home is feasible for detecting respiratory infections and supports creating a decentralised household-based cohort for pandemic preparedness.

Bipolar Disorder Linked to Higher Mortality in Older Adults

Bipolar disorder is associated with a 72% increased risk for mortality over 8 years in older adults compared with the general population, a new prospective study shows.

Prostate Surgery Leakage Improves Over 12 Months

About 1 in 5 patients develop urinary incontinence 3 months after thulium fiber laser enucleation of the prostate, with rates decreasing over 12 months.

Age and MRI Features Predict MS Odds After Initial Symptoms

Younger age at onset, multifocal symptoms, and specific MRI findings are associated with increased odds of multiple sclerosis diagnosis after a first demyelinating event.

Nirsevimab Linked to Lower Risk for IPD Hospitalizations

Nirsevimab immunization in children younger than 12 months is linked to a lower risk for hospitalization for invasive pneumococcal disease, a French nationwide analysis shows.

‘Big Beautiful’ Law Tests Rural Hospital Lifeline

A century-old hospital near Michigan’s southern border was one of the nation’s first to convert into a new emergency-focused model Congress created to save rural care.

Romanian Healthcare Workers End Strike Over Pay, Staffing

Romanian healthcare workers ended a nationwide strike on ⁠Friday as the country's caretaker government approved new hires in ⁠short-staffed state hospitals.

Swimming Linked to Reduced Disability in Low Back Pain

Swimming plus education is more effective than education alone in reducing disability in adults with chronic low back pain over 8 weeks, a trial shows.

Preterm Lung Disease: One Drug Testing May Miss Responders

Most children born premature with chronic lung disease have reversible airway obstruction, but bronchodilator responses vary widely, underscoring the need for individualized testing.

Vancomycin Prophylaxis Tied to Lower C difficile Recurrence

In children and young adults with cancer, oral vancomycin prophylaxis during broad-spectrum antibiotic therapy is associated with a lower risk for recurrent Clostridioides difficile infection.

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