Neoadjuvant immunotherapy improves outcomes in high-risk melanoma patients.

Published Date: 02 Mar 2023

High-risk melanoma patients who received the drug pembrolizumab before or after surgery to remove the cancer had a higher risk of developing melanoma than those who did not have a similar condition that eliminated cancer cells.

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Prostate Surgery Leakage Improves Over 12 Months

About 1 in 5 patients develop urinary incontinence 3 months after thulium fiber laser enucleation of the prostate, with rates decreasing over 12 months.

Age and MRI Features Predict MS Odds After Initial Symptoms

Younger age at onset, multifocal symptoms, and specific MRI findings are associated with increased odds of multiple sclerosis diagnosis after a first demyelinating event.

Nirsevimab Linked to Lower Risk for IPD Hospitalizations

Nirsevimab immunization in children younger than 12 months is linked to a lower risk for hospitalization for invasive pneumococcal disease, a French nationwide analysis shows.

‘Big Beautiful’ Law Tests Rural Hospital Lifeline

A century-old hospital near Michigan’s southern border was one of the nation’s first to convert into a new emergency-focused model Congress created to save rural care.

Romanian Healthcare Workers End Strike Over Pay, Staffing

Romanian healthcare workers ended a nationwide strike on ⁠Friday as the country's caretaker government approved new hires in ⁠short-staffed state hospitals.

Swimming Linked to Reduced Disability in Low Back Pain

Swimming plus education is more effective than education alone in reducing disability in adults with chronic low back pain over 8 weeks, a trial shows.

Todays Updates

Jazz Seeks Second-Line Lurbinectedin SCLC Withdrawal

The planned label change follows failure of lurbinectedin to improve overall survival in the phase 3 postmarketing trial; the first-line maintenance indication remains unaffected.

Todays Updates

Jazz Seeks Second-Line Lurbinectedin SCLC Withdrawal

The planned label change follows failure of lurbinectedin to improve overall survival in the phase 3 postmarketing trial; the first-line maintenance indication remains unaffected.

Latest News

About 1 in 5 patients develop urinary incontinence 3 months after thulium fiber laser enucleation of the prostate, with rates decreasing over 12 months.

Younger age at onset, multifocal symptoms, and specific MRI findings are associated with increased odds of multiple sclerosis diagnosis after a first demyelinating event.

Nirsevimab immunization in children younger than 12 months is linked to a lower risk for hospitalization for invasive pneumococcal disease, a French nationwide analysis shows.

A century-old hospital near Michigan’s southern border was one of the nation’s first to convert into a new emergency-focused model Congress created to save rural care.

Romanian healthcare workers ended a nationwide strike on ⁠Friday as the country's caretaker government approved new hires in ⁠short-staffed state hospitals.

Swimming plus education is more effective than education alone in reducing disability in adults with chronic low back pain over 8 weeks, a trial shows.

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Online Harassment: Should Doctors Stay on Social Media?

Online harassment increasingly targets physicians who share evidence-based information, prompting calls for stronger institutional support and safer public engagement.

Post-Pandemic Burnout: NP, PAs Face Different Challenges

The struggles advanced practice practitioners face are different than those that physicians deal with. But the threats are the same.

Ethical Conflict Common in Maternity Care

Providers who work as midwives, in both inpatient and outpatient settings, in southern US states, or who do not have kids may face the most ethical conflicts over drug testing and child welfare reporting.

Sugammadex Reduces Post-Op Lung Complications

Reversal of neuromuscular block with sugammadex reduces the risk for post-op pulmonary complications or death compared with neostigmine in older adults undergoing major abdominal or thoracic surgery.

Faricimab May Aid Hard-to-Treat Macular Degeneration Cases

Faricimab may stabilize vision, reduce retinal fluid and thickness, and cut treatment burden in difficult-to-treat cases of wet age-related macular degeneration.

Delays Harmless for Most Macular Degeneration Patients

Waiting for prior authorization of drugs affects a small portion of patients with age-related macular degeneration, resulting in vision loss.

Sri Lanka Uses Air Force Drones to Tackle Spreading Dengue Outbreak

Sri Lanka's public health services and hospitals are battling the worst outbreak of mosquito-borne dengue in nearly a decade, and turning to the island nation's armed...

A 3-Week Steroid Course Falls Short in Pneumonitis

In patients with mild immune-related pneumonitis, a shorter 3-week corticosteroid regimen does not meet noninferiority compared with the standard 6-week taper.

Cefazolin Noninferior to Penicillins for MSSA Bacteremia

Cefazolin is noninferior to antistaphylococcal penicillins for methicillin-susceptible Staphylococcus aureus bacteremia and is associated with a lower risk for acute kidney injury.

Tentacular Cyclosporiasis Outbreak Stymies Epidemiology Efforts

Confirmed case count across 34 states is five times the number reported last summer, the CDC says.

Transport Of Dead Bodies Within Congo Risks Further Ebola Spread, UN Agency Warns

The transport of Ebola victims' bodies between different areas of the Democratic Republic of Congo, often for funerals in their home communities, risks further ⁠spreading...

Noninvasive Ventilation May Lower Tracheostomy Need in BPD

In preemies with bronchopulmonary dysplasia on home respiratory support, noninvasive positive airway pressure is linked to shorter hospital stays and less healthcare use than tracheostomy ventilation.

Ensitrelvir Reduces COVID Risk Among Contacts Post-Exposure

Household contacts who initiate ensitrelvir vs placebo within 72 hours of symptom onset in the index patient have lower risk of developing COVID, with no apparent safety concerns.

How to Teach Professionalism? Ditch the Deficiency Focus

Teaching professionalism in medical school is required, but how best to do it? Move beyond a deficiency focus, experts say. Emphasize positive examples of professionalism.

Anemia Leads List of Factors That Affect BLVR Failure

Recognizing the impact of comorbidities may guide patient selection and improve outcomes.

Paid Parental Leave for Med School Faculty Often Lacking

Many medical schools don’t offer nationally recommended levels of paid parental leave.

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