Neoadjuvant immunotherapy improves outcomes in high-risk melanoma patients.

Published Date: 02 Mar 2023

High-risk melanoma patients who received the drug pembrolizumab before or after surgery to remove the cancer had a higher risk of developing melanoma than those who did not have a similar condition that eliminated cancer cells.

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Can Sexual Experience Reshape the Brain?

New research is exploring whether sexual experience may shape brain circuits linked to reward, learning, and mood — but the human evidence remains early.

Somatic Mutations Shape Systemic Autoinflammatory Disease

Acquired somatic variants may drive over 20% of systemic autoinflammatory disease diagnoses, with VEXAS syndrome and cryopyrin-associated periodic syndromes representing the majority of cases.

Sonographer Shortage Is Affecting Expectant Women’s Health

A sonographer shortage confronts expectant women in Ontario with long commutes for routine ultrasounds.

How Clinicians Can Improve STI Conversations

A Spanish sexologist says the key to better STI detection may be simpler than it seems: create a safe, nonjudgmental space and ask directly.

Ultrasound Expands Options for Chest Lesion Biopsy

A radiation-sparing procedure shows a safe and effective diagnostic potential.

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‘Modest’ Differences in OAT Should Not Obscure Benefits

Methadone may be linked to a lower risk for death than buprenorphine-naloxone in the short term, but after an overdose, either opioid agonist therapy is better than none.

Talc Powder Not Linked to Lung Cancer in Women

A study of US women finds no connection between talc powder use and lung cancer, though subgroup findings leave questions open.

Todays Updates

‘Modest’ Differences in OAT Should Not Obscure Benefits

Methadone may be linked to a lower risk for death than buprenorphine-naloxone in the short term, but after an overdose, either opioid agonist therapy is better than none.

Talc Powder Not Linked to Lung Cancer in Women

A study of US women finds no connection between talc powder use and lung cancer, though subgroup findings leave questions open.

Latest News

Groups such as the ACR object to a CMS ‘frailty-exemption’ rule intended to make clinicians try to judge patients’ ability to work, noting among their objections a lack of adequate tools for this task.

New research is exploring whether sexual experience may shape brain circuits linked to reward, learning, and mood — but the human evidence remains early.

Acquired somatic variants may drive over 20% of systemic autoinflammatory disease diagnoses, with VEXAS syndrome and cryopyrin-associated periodic syndromes representing the majority of cases.

A sonographer shortage confronts expectant women in Ontario with long commutes for routine ultrasounds.

A Spanish sexologist says the key to better STI detection may be simpler than it seems: create a safe, nonjudgmental space and ask directly.

A radiation-sparing procedure shows a safe and effective diagnostic potential.

News All Time

Paternal Valproate Use Not Tied to NDDs in Offspring

Paternal exposure to valproate during spermatogenesis is not tied to a risk for neurodevelopmental disorders or congenital malformations in offspring, research shows.

Early Oseltamivir Tied to Lower Hospitalization Risk in Flu

Among adult veterans, oseltamivir treatment initiated within 6 hours of influenza diagnosis is associated with a reduced risk for hospitalization.

AI Outperforms Gene Sequencing for Lung Nodule Triage

Interpret findings with caution, but AI-based radiomics may help curb unnecessary procedures.

Discharge Support Remains Weak Spot in CQC Patient Survey

The CQC's 2025 survey of 58,000 patients found rising satisfaction overall, but discharge planning remains an area of difficulty.

Canadian Bill Intended to Close Gaps in Women’s Healthcare

The comprehensive bill takes a multipronged approach to improving women’s health within a framework intended to keep future governments accountable.

Are Universal Digital Mental Health Interventions Effective?

In children without diagnosed mental health conditions, digital interventions are associated with small psychological improvements.

West Nile Virus Infection Causes One Death in the Netherlands

A person has died in a Dutch hospital after ⁠contracting the West Nile virus in the Netherlands, the country's public ⁠health institution RIVM said on...

Statins Tied to Fewer Respiratory Infections in Older Adults

Among older adults unvaccinated against influenza, starting statins is associated with a lower risk for hospitalisation with pneumonia or other acute respiratory infections.

GCA Patients Often Need Long-Term Glucocorticoids

Despite rapid diagnosis and guideline-based tapering, a substantial proportion of patients with giant cell arteritis remain dependent on glucocorticoid therapy for years.

Artificial Intelligence Boosts Automated Biolabs

AI and machine learning are kicking synthetic biology up to new levels of innovation. Researchers see huge potential for novel drugs and other chemicals; some also see risks.

Hospital Medicine: Good Onboarding of Hospitalists Pays Off

In years past, new hospitalists got a brief orientation and went to work. A more comprehensive approach — onboarding — is now the norm. It pays off in ways other than the bottom line.

Can Conversational AI Platforms Free Up Physicians’ Time?

Conversational agents are taking on scheduling, intake, and follow-ups, whereas clinics assess whether automation can ease administrative demands on physicians.

Branded Bevacizumab: Retina Breakthrough or Bankbuster?

Bevacizumab is a cornerstone retina drug that has been used off-label for decades. Where the FDA-cleared branded version fits in may be a matter of cost and acceptance.

Worker Violence, Staff Shortages Spark Hospital Strikes

Healthcare workers are facing more violence and staff shortages, fueling hospital strikes as workers push for safer workplaces and enough staff to care for patients.

Retinal Thinning Predicts Cognitive Decline in MS

Thinning of specific retinal layers predicts cognitive worsening in patients with multiple sclerosis, even without disease relapses — suggesting the eye may reveal hidden neurodegeneration.

Intensive Nurse-Led Supportive Care Tied to Better QOL

Higher nurse-led supportive care intensity is associated with a better quality of life and lower symptom burden in patients receiving palliative chemotherapy, a study reports.

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