Neoadjuvant immunotherapy improves outcomes in high-risk melanoma patients.

Published Date: 02 Mar 2023

High-risk melanoma patients who received the drug pembrolizumab before or after surgery to remove the cancer had a higher risk of developing melanoma than those who did not have a similar condition that eliminated cancer cells.

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Punchlines and Pathology: The Secrets of Laughter Explained

A new review of data from patients with epilepsy describes two distinct neural networks, offering clinicians and patients a way to better understand laughter as a neurologic malfunction.

Gene Therapy Delivers Sustained Retinal Protection

People with age-related macular degeneration maintain vision and cut their need for supplemental injections by 90% 5 years after receiving gene therapy.

Online Harassment: Should Doctors Stay on Social Media?

Online harassment increasingly targets physicians who share evidence-based information, prompting calls for stronger institutional support and safer public engagement.

Post-Pandemic Burnout: NP, PAs Face Different Challenges

The struggles advanced practice practitioners face are different than those that physicians deal with. But the threats are the same.

Ethical Conflict Common in Maternity Care

Providers who work as midwives, in both inpatient and outpatient settings, in southern US states, or who do not have kids may face the most ethical conflicts over drug testing and child welfare reporting.

Sugammadex Reduces Post-Op Lung Complications

Reversal of neuromuscular block with sugammadex reduces the risk for post-op pulmonary complications or death compared with neostigmine in older adults undergoing major abdominal or thoracic surgery.

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Palliative Care Remains Uncommon in Young Adults With Cancer

Concurrent palliative care use among young adults with advanced cancer is less than 20%, with substantial variation across cancer types.

Todays Updates

Palliative Care Remains Uncommon in Young Adults With Cancer

Concurrent palliative care use among young adults with advanced cancer is less than 20%, with substantial variation across cancer types.

Latest News

A new review of data from patients with epilepsy describes two distinct neural networks, offering clinicians and patients a way to better understand laughter as a neurologic malfunction.

People with age-related macular degeneration maintain vision and cut their need for supplemental injections by 90% 5 years after receiving gene therapy.

Online harassment increasingly targets physicians who share evidence-based information, prompting calls for stronger institutional support and safer public engagement.

The struggles advanced practice practitioners face are different than those that physicians deal with. But the threats are the same.

Providers who work as midwives, in both inpatient and outpatient settings, in southern US states, or who do not have kids may face the most ethical conflicts over drug testing and child welfare reporting.

Reversal of neuromuscular block with sugammadex reduces the risk for post-op pulmonary complications or death compared with neostigmine in older adults undergoing major abdominal or thoracic surgery.

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Anemia Leads List of Factors That Affect BLVR Failure

Recognizing the impact of comorbidities may guide patient selection and improve outcomes.

Paid Parental Leave for Med School Faculty Often Lacking

Many medical schools don’t offer nationally recommended levels of paid parental leave.

Congo's Ebola Outbreak Spreads to Two More Provinces

The Ebola outbreak in the Democratic Republic of Congo has spread to two more northeastern provinces, Haut-Uele ⁠and Tshopo, the country's public health institute said in...

‘Super Movers’ May Have Slower Cognitive Decline

Fast-walking ‘super movers’ aged 80 years or older have about half the risk for cognitive impairment but no less Alzheimer’s disease pathology.

Sanofi to Stop Disparaging Rival Flu Vaccine to Stave Off EU Antitrust Fine

French pharmaceutical company Sanofi has offered to state publicly that ⁠a rival flu vaccine is as effective as its own, EU antitrust regulators said on Wednesday of the...

India's Dr Reddy's Says Semaglutide Shipping Disruption to Last Until At Least Late October

India's Dr Reddy's Laboratories said on Thursday that supplies of its generic semaglutide would remain unavailable in India and face disruptions in Canada until at least...

RSV Preventive Strategies Tied to Fewer Bronchiolitis Cases

Administration of nirsevimab and RSV vaccination in pregnant women are tied to significant reductions in hospitalized days and oxygen requirements among infants with bronchiolitis.

Light Activity Pays Off for COPD Survival

New data show that patients need not exercise intensely to improve outcomes.

Initial Prescription Duration May Shape Benzodiazepine Use

Longer durations of initial prescriptions are associated with prolonged use of benzodiazepines compared with durations of 7 days or less, a large cohort study shows.

Alcohol’s Health Myth Is Over. How to Tell Patients

The science on alcohol has changed dramatically. Here’s how experts say physicians can explain why older advice no longer holds up — and counsel patients without judgment.

US House Committee Opens Investigation Into Merck, AbbVie China Drug Trials

The chair of the U.S. House Select Committee on China opened national security investigations into whether five drugmakers including Merck and AbbVie have been involved in...

Bepirovirsen Achieves Functional Cure in HBV Phase 3 Trial

In patients with chronic hepatitis B infection, bepirovirsen achieves significantly higher rates of functional cure than placebo after discontinuation of nucleoside or nucleotide analog therapy.

Retina Care Visits Reveal High BP in Adults With Diabetes

Many adults with diabetes have uncontrolled or previously undiagnosed high blood pressure during their routine visits to retina clinics, prompting referrals and urgent follow-up, a study finds.

Venezuela Health System Strained After Earthquakes, WHO Says

Venezuela's healthcare system is under significant strain, ⁠the World Health Organization said on Tuesday, with some hospitals damaged and ⁠others missing staff after deadly...

Evidence for tVNS Stronger for Anxiety Than Cognition

Transcutaneous vagus nerve stimulation was associated with reduced anxiety severity but showed no significant benefit for working memory or inhibitory control in healthy adults.