Neoadjuvant immunotherapy improves outcomes in high-risk melanoma patients.

Published Date: 02 Mar 2023

High-risk melanoma patients who received the drug pembrolizumab before or after surgery to remove the cancer had a higher risk of developing melanoma than those who did not have a similar condition that eliminated cancer cells.

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Statins Tied to Fewer Respiratory Infections in Older Adults

Among older adults unvaccinated against influenza, starting statins is associated with a lower risk for hospitalisation with pneumonia or other acute respiratory infections.

GCA Patients Often Need Long-Term Glucocorticoids

Despite rapid diagnosis and guideline-based tapering, a substantial proportion of patients with giant cell arteritis remain dependent on glucocorticoid therapy for years.

Artificial Intelligence Boosts Automated Biolabs

AI and machine learning are kicking synthetic biology up to new levels of innovation. Researchers see huge potential for novel drugs and other chemicals; some also see risks.

Hospital Medicine: Good Onboarding of Hospitalists Pays Off

In years past, new hospitalists got a brief orientation and went to work. A more comprehensive approach — onboarding — is now the norm. It pays off in ways other than the bottom line.

Can Conversational AI Platforms Free Up Physicians’ Time?

Conversational agents are taking on scheduling, intake, and follow-ups, whereas clinics assess whether automation can ease administrative demands on physicians.

Branded Bevacizumab: Retina Breakthrough or Bankbuster?

Bevacizumab is a cornerstone retina drug that has been used off-label for decades. Where the FDA-cleared branded version fits in may be a matter of cost and acceptance.

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Sequencing Method Flags AML Relapse Risk Around Transplant

High-sensitivity tracking of a high-risk mutation may help identify risk for relapse in patients with acute myeloid leukemia around the time of allogeneic transplant.

Todays Updates

Sequencing Method Flags AML Relapse Risk Around Transplant

High-sensitivity tracking of a high-risk mutation may help identify risk for relapse in patients with acute myeloid leukemia around the time of allogeneic transplant.

Latest News

Among older adults unvaccinated against influenza, starting statins is associated with a lower risk for hospitalisation with pneumonia or other acute respiratory infections.

Despite rapid diagnosis and guideline-based tapering, a substantial proportion of patients with giant cell arteritis remain dependent on glucocorticoid therapy for years.

AI and machine learning are kicking synthetic biology up to new levels of innovation. Researchers see huge potential for novel drugs and other chemicals; some also see risks.

In years past, new hospitalists got a brief orientation and went to work. A more comprehensive approach — onboarding — is now the norm. It pays off in ways other than the bottom line.

Conversational agents are taking on scheduling, intake, and follow-ups, whereas clinics assess whether automation can ease administrative demands on physicians.

Bevacizumab is a cornerstone retina drug that has been used off-label for decades. Where the FDA-cleared branded version fits in may be a matter of cost and acceptance.

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Microcytic Anemia Patterns Differ by Sex in Teens

Adolescent females show a steady increase in the prevalence of microcytic anemia throughout their teenage years, while males show the opposite trend.

Whole Foods Recalls Items Containing Jalapenos on Potential Salmonella Contamination

Whole Foods said on Wednesday it was recalling select products from its produce and prepared foods departments that contain jalapenos ⁠sourced from Coast Citrus Distributors...

Med Schools Welcome Class of 2030 With White Coat Ceremonies

Thousands of newly minted med students took the first steps on their journey in medicine.

Gaza Cancer Patients Face Rising Death Rate Amid Israeli Curbs

Gaza cancer patients are dying at two to three times the pace they did before the start of the war in the territory, as Israel blocks many from travelling for treatment.

Living Near a Dry Cleaner Tied to Higher PD Risk

Living within 500 ft of a dry cleaner is linked to a 14% increased PD risk for vs living 4-5 miles away, with the strongest associations seen in certain US regions and in the gait-instability subtype.

Defining COPD Phenotypes With Advanced Imaging

Visual characteristics of lung disease are helping pulmonologists establish care plans and interventions.

Triple Therapy Reduces Antibiotic Use in Pediatric CF

A triple-combination therapy targeting the underlying defect in cystic fibrosis was associated with a dramatic reduction in antibiotic exposure among children and adolescents.

NHS Rehab Cuts Leaving Patients With ‘Avoidable Disability’

Recruitment freezes and lost rehab space are harming patient care, a CSP survey of 548 NHS physiotherapists finds.

ACARD Score Predicts Mortality in Status Epilepticus

A newly developed prognostic tool outperforms existing scoring systems in predicting short-term mortality risk following status epilepticus.

THC Safe, Effective for PTSD-Related Nightmares

Dronabinol, a medication containing THC, is linked to fewer nightmares at lower intensity compared to placebo in patients with post-traumatic stress disorder, new data show.

French Hospital Brings Phage Therapy Closer to Clinical Use

A first-in-world public authorization to manufacture GMP therapeutic phages could expand clinical trials, strengthen regulated access, and accelerate evidence-based treatment.

Self-Sampling Can Be Feasible for Respiratory Infections

A Swiss pilot study shows that self-sampling at home is feasible for detecting respiratory infections and supports creating a decentralised household-based cohort for pandemic preparedness.

Bipolar Disorder Linked to Higher Mortality in Older Adults

Bipolar disorder is associated with a 72% increased risk for mortality over 8 years in older adults compared with the general population, a new prospective study shows.

Age and MRI Features Predict MS Odds After Initial Symptoms

Younger age at onset, multifocal symptoms, and specific MRI findings are associated with increased odds of multiple sclerosis diagnosis after a first demyelinating event.

Prostate Surgery Leakage Improves Over 12 Months

About 1 in 5 patients develop urinary incontinence 3 months after thulium fiber laser enucleation of the prostate, with rates decreasing over 12 months.

Nirsevimab Linked to Lower Risk for IPD Hospitalizations

Nirsevimab immunization in children younger than 12 months is linked to a lower risk for hospitalization for invasive pneumococcal disease, a French nationwide analysis shows.