NeurologyLive® Brain Games : 12 mars 2023

Published Date: 16 Mar 2023

Test your neurology knowledge with NeurologyLive®'s weekly quiz featuring questions on a variety of clinical and neurological history topics. This week's theme is movement.

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Latest News

Self-Administered Med Shows Promise in Myasthenia Gravis

Weekly subcutaneous gefurulimab delivered early is linked to lasting symptom improvement in patients with generalized myasthenia gravis in phase 3 PREVAIL trial.

Novel PD Drug May Delay Levodopa Initiation

Tavapadon may delay levodopa use in early Parkinson’s and help stabilize dosing in the later stages of the disease, with most patients avoiding initiation or dose increases.

Tau Blood Test Detects AD Risk Years Before Brain Changes

Plasma pTau217 may detect initial buildup of AD-related brain changes before they can be detected by current ‘gold standard’ tests, such as PET scans, new research shows.

Novel Kv7 Channel Opener Reduces Seizures Without Titration

In a phase 3 trial, the agent reduces seizure frequency by up to 53% in treatment-resistant focal epilepsy, with rapid onset and a favorable safety profile.

US FDA's Accelerated Approval for Drugs Needs More Transparency, Says Research Firm

The U.S. Food and Drug Administration should be more transparent when granting accelerated approval for certain drugs, influential drug pricing body, Institute for Clinical...

Common Genetic Cause of Intellectual Disability Identified

A newly identified recessive neurodevelopmental disorder may be among the most common genetic causes of intellectual disability and epilepsy, new research suggests.

Todays Updates

AstraZeneca to Invest $405 Million in Britain After US-UK Pharma Deal

Prime Minister Keir Starmer said on Wednesday that Britain's biggest company AstraZeneca would invest 300 million pounds ($405 ⁠million) in the country, after pausing...

Upadacitinib After TNF Inhibitor Failure Improves RA Control

In patients with active RA, switching to upadacitinib after failure of a single TNF inhibitor is more effective in reducing disease activity at 12 weeks than using a second TNF inhibitor adalimumab.

AAN 2026: Key RRMS Clinical Trial Updates

Dr Chu-Yueh Guo discusses promising MS trial results, including a study of fenebrutinib and positive safety data for ocrelizumab in pregnancy and pediatric patients.

Are Smartwatches Changing Arrhythmia Care?

Wearables can flag AF and capture symptoms in real time — but who truly benefits? Cardiologist Walid Amara, MD, outlines where smartwatches fit in clinical practice.

Why the FDA Rejected RP-1 in Melanoma: A Data Deep Dive

Dr Bishal Gyawali unpacks the FDA’s decision to deny RP-1 in melanoma, exploring why single-arm data and confounded response rates failed to meet the bar for clinical evidence.

Differential Diagnosis of Suspected Pulmonary Fibrosis and Efficacy of Approved Therapies

Experts review the differential diagnosis of suspected IPF, highlighting how a multidisciplinary approach confirmed the diagnosis and informed selection of optimal antifibrotic therapy.

‘Living’ Database Tracks Psilocybin Trials for Depression

Sypres.io continuously tracks and evaluates psychedelic research, offering an up-to date view of study findings, design, and limitations.

Todays Updates

AstraZeneca to Invest $405 Million in Britain After US-UK Pharma Deal

Prime Minister Keir Starmer said on Wednesday that Britain's biggest company AstraZeneca would invest 300 million pounds ($405 ⁠million) in the country, after pausing...

Upadacitinib After TNF Inhibitor Failure Improves RA Control

In patients with active RA, switching to upadacitinib after failure of a single TNF inhibitor is more effective in reducing disease activity at 12 weeks than using a second TNF inhibitor adalimumab.

AAN 2026: Key RRMS Clinical Trial Updates

Dr Chu-Yueh Guo discusses promising MS trial results, including a study of fenebrutinib and positive safety data for ocrelizumab in pregnancy and pediatric patients.

Are Smartwatches Changing Arrhythmia Care?

Wearables can flag AF and capture symptoms in real time — but who truly benefits? Cardiologist Walid Amara, MD, outlines where smartwatches fit in clinical practice.

Why the FDA Rejected RP-1 in Melanoma: A Data Deep Dive

Dr Bishal Gyawali unpacks the FDA’s decision to deny RP-1 in melanoma, exploring why single-arm data and confounded response rates failed to meet the bar for clinical evidence.

Differential Diagnosis of Suspected Pulmonary Fibrosis and Efficacy of Approved Therapies

Experts review the differential diagnosis of suspected IPF, highlighting how a multidisciplinary approach confirmed the diagnosis and informed selection of optimal antifibrotic therapy.

‘Living’ Database Tracks Psilocybin Trials for Depression

Sypres.io continuously tracks and evaluates psychedelic research, offering an up-to date view of study findings, design, and limitations.

Latest News

Weekly subcutaneous gefurulimab delivered early is linked to lasting symptom improvement in patients with generalized myasthenia gravis in phase 3 PREVAIL trial.

Tavapadon may delay levodopa use in early Parkinson’s and help stabilize dosing in the later stages of the disease, with most patients avoiding initiation or dose increases.

Plasma pTau217 may detect initial buildup of AD-related brain changes before they can be detected by current ‘gold standard’ tests, such as PET scans, new research shows.

In a phase 3 trial, the agent reduces seizure frequency by up to 53% in treatment-resistant focal epilepsy, with rapid onset and a favorable safety profile.

The U.S. Food and Drug Administration should be more transparent when granting accelerated approval for certain drugs, influential drug pricing body, Institute for Clinical...

A newly identified recessive neurodevelopmental disorder may be among the most common genetic causes of intellectual disability and epilepsy, new research suggests.

News All Time

Anxiety and Depression May Raise Risk for Aneurysm Rupture

Anxiety and depression are linked to an increased risk for rupture and mortality in patients with unruptured intracranial aneurysms, a new cohort study shows.

China Approves Market Launch Of Brain-computer Interface Medical Device in World First

China's drug regulator said on Friday that it has given the nod for a brain-computer interface (BCI) system ⁠that helps restore hand-movement ability to be sold, the world's...

Why Aren’t Canadians Getting Enough Sleep?

The change to daylight saving time and the marking of World Sleep Day call attention to the factors that contribute to sleep deficits among Canadians.

Single IV Ketamine Promising for Depression in MCI

Ketamine is well-tolerated in older adults with both mild cognitive impairment and depression and associated with improved depression scores, a new study shows.

Late Complications Common After CVT, Even After Recovery

Although a majority of patients with cerebral venous sinus thrombosis achieve independence, 1 in 3 may develop delayed complications such as seizures, a study shows.

Activity Trackers May Predict MS Progression

Reduced daytime physical activity, as measured with wearable trackers, is tied to increased risk for multiple sclerosis progression and brain atrophy, new research shows.

WHO Warns Of Health Risks From 'Black Rain' in Iran

The World Health Organization warned on Tuesday that the 'black rain' and toxic compounds in the air in Iran after strikes on ⁠oil facilities could cause respiratory problems.

Wildfire Smoke Tied to Higher Stroke Risk, Greater Severity

Short-term surges in air pollution from wildfire smoke have been linked to a greater incidence and severity of stroke.

Therapeutic Research in Alzheimer’s Disease: What Is New?

Long-term extension trial results with donanemab suggest a widening separation in cognitive decline through 36 months in early Alzheimer’s disease.

Reframing Dyslexia: Ancient Genes, Modern Skill

Study argues to move beyond ‘reading genes’ — focus on conserved neural-development networks in humans to improve early screening and identify therapeutic leads.

Adults With IDDs Face ‘Mental Health Crisis’

Adults with IDDs face disproportionately higher rates of anxiety and depression and barriers to care, prompting researchers to characterize the situation as a ‘mental health crisis.’

Smoking + Parkinson's: Lower Disease Risk, Higher Mortality

A large nationwide study revisits the smoking-Parkinson's paradox, linking current smoking to lower disease risk but linking quitting to lower all-cause mortality.

Positive Topline Results for Efgartigimod in Ocular MG

Efgartigimod led to statistically significant improvement in key symptoms of ocular myasthenia gravis compared with placebo in a phase 3 trial.

Stem Cell Therapy Safe, Feasible in Spina Bifida

A first-in-human trial shows the feasibility and safety of delivering placenta-derived stem cells during prenatal myelomeningocele repair.

Does Caring for Grandchildren Slow Cognitive Decline?

Grandmothers who care for grandchildren show slower cognitive decline over time than non-caregivers do.

Teen Cannabis Use Tied to Increase in Serious Mental Illness

A new study shows that teens with past-year cannabis use are twice as likely to be diagnosed with psychotic or bipolar disorders within 2 years of first use.

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