Sep 18 2026 This Week in Cardiology

Published Date: 19 Sep 2026

Another ESC recap, listener feedback on two trials, and a paper on GLP-1 effects on inflammation from the SELECT trial are the topics John Mandrola, MD, discusses in this week’s podcast.

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Latest News

Time to REACT Earlier: Is CVD Prevention Starting Too Late?

How reassuring is a low 10-year CV risk? REACT reveals how early silent atherosclerosis begins and asks whether CVD prevention should start sooner.

Never Too Late (or Too Early) for Lipid Lowering

ESC studies on statin use in patients over 70 years and identifying subclinical atherosclerosis via 3D ultrasonography of the carotid and femoral arteries and coronary CTA are discussed.

Narrative Videos to Improve Lung Cancer Screening Uptake

Short, veteran-led clips could stem fear, anxiety associated with screening

What the 2026 ESC Guidelines Mean for Primary Care

The guideline update is a revolution that will promote evidence-based, person-centered classification and management of heart failure.

Sep 11 2026 This Week in Cardiology

A second ESC recap plus two breaking stories on the failure of an investigational Lp(a) reducing drug and a new FDA approval of an AI-ECG app are covered by John Mandrola, MD

Nothing to Shrug About: Shoulder Reproducibility with SGRT

A pilot study suggests open-face SGRT immobilization is feasible for HN radiotherapy, with shoulder reproducibility similar to conventional masks.

Todays Updates

Q3 2026 Recap: Psychiatry News and Updates

Q3 2026 Recap: Psychiatry News and Updates

CSF Biomarkers Identify Shared LRRK2 Pathway Activation in Sporadic and LRRK2-Associated Parkinson Disease Louie Pasculli

New cerebrospinal fluid biomarker data suggest shared LRRK2 pathway activation across sporadic and LRRK2-associated Parkinson disease, potentially informing biomarker development and therapeutic targeting.

Navigating Corticosteroid Stewardship in Dermatology, With Kristina Derrick, MD Kristina Derrick, MD

Kristina Derrick, MD, explains how prior authorization and cost limit steroid-sparing care, and how dermatologists can document corticosteroid exposure.

Denifanstat Sustains Acne Control Through 52 Weeks, With Neal Bhatia, MD Neal Bhatia, MD

Bhatia discusses 52-week extension data showing denifanstat sustained acne control with a favorable long-term safety profile, presented at EADV 2026.

Todays Updates

Q3 2026 Recap: Psychiatry News and Updates

Q3 2026 Recap: Psychiatry News and Updates

CSF Biomarkers Identify Shared LRRK2 Pathway Activation in Sporadic and LRRK2-Associated Parkinson Disease Louie Pasculli

New cerebrospinal fluid biomarker data suggest shared LRRK2 pathway activation across sporadic and LRRK2-associated Parkinson disease, potentially informing biomarker development and therapeutic targeting.

Navigating Corticosteroid Stewardship in Dermatology, With Kristina Derrick, MD Kristina Derrick, MD

Kristina Derrick, MD, explains how prior authorization and cost limit steroid-sparing care, and how dermatologists can document corticosteroid exposure.

Denifanstat Sustains Acne Control Through 52 Weeks, With Neal Bhatia, MD Neal Bhatia, MD

Bhatia discusses 52-week extension data showing denifanstat sustained acne control with a favorable long-term safety profile, presented at EADV 2026.

Latest News

How reassuring is a low 10-year CV risk? REACT reveals how early silent atherosclerosis begins and asks whether CVD prevention should start sooner.

ESC studies on statin use in patients over 70 years and identifying subclinical atherosclerosis via 3D ultrasonography of the carotid and femoral arteries and coronary CTA are discussed.

Short, veteran-led clips could stem fear, anxiety associated with screening

The guideline update is a revolution that will promote evidence-based, person-centered classification and management of heart failure.

A second ESC recap plus two breaking stories on the failure of an investigational Lp(a) reducing drug and a new FDA approval of an AI-ECG app are covered by John Mandrola, MD

A pilot study suggests open-face SGRT immobilization is feasible for HN radiotherapy, with shoulder reproducibility similar to conventional masks.

News All Time

When Grief Was Called Hysteria

A young woman grieving a miscarriage was labeled "hysteria." Dr Loshi Rajen reflects on diagnostic bias, the enduring power of psychiatric labels, and the importance of recognizing normal grief.

The Heart of the Matter

How a cardiac procedure exposed the tension between a mother’s autonomy and her son’s medical expertise.

The Dose Is Too High: Rethinking TKI Dosing

Standard TKI doses are often too high for long-term care. Dr Mark Kris shares his strategy for smart dose reductions that protect patient outcomes.

Optimizing Therapy in Early Stage HER2+ Breast Cancer

Cure rates are climbing, and so is the complexity of getting there. Dr Yara Abdou takes a closer look at optimizing HER2+ early-stage breast cancer therapy.

The ‘Pack-Year’ Approach to Cardiac Risk Management

The Curbsiders share practical insights on navigating complex cardiac risk factors and optimizing cholesterol.

The Looming 100-Million Cancer Workforce Crisis

Global workforce inequities are widening the cancer survival gap. Prof David Kerr highlights the stark realities and calls for an improved training approach.

Are Smart Glasses the Future of Collaborative Surgery?

Orthopedic surgeon Amgad Nakhla is using smart glasses in theater to bring remote expertise into com-plex cases and support real-time decisions.

Thyroid: A Year in Review

Drs Kaniksha Desai and Anupam Kotwal discuss thyroid: a year in review.

Fast Five Quiz: PPF Management

What do you know about the management for progressive pulmonary fibrosis? Test your knowledge with this quick quiz.

CT Radiation Risk: Is it Time to Rethink Imaging?

Two high-impact studies link routine CT scans to significant lifetime cancer risks. Dr Maurie Markman discusses why we can no longer ignore the data.

Preview: New Thyroid Nodule Guidelines

Drs Kaniksha Desai and Victor Bernet discuss the new guidelines for thyroid nodules.

Migraine and Stroke: What's the Real Risk?

Neurologist Indu Subramanian and migraine expert Andrew Charles discuss the risk for stroke in patients with migraine.

De-Escalated Treatment for Early Breast Cancer Continues to Gain Momentum

More patients of all ages skip sentinel lymph node biopsy, get less aggressive RT or none at all

Creeping Gradients After TAVR Linked to Poor Longer-Term Outcomes

Registry tracked incidence, prognostic impact of early hemodynamic valve deterioration

Pancreatic Cancer Risk Much Higher for Certain Group, Study Suggests

Long-term follow-up of low-risk pancreatic cystic lesions may be necessary

Tile-Based Radiation Tops Standard for Resected Brain Metastases

Approach significantly improved local control, and longer survival observed in trial

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EU Adds CAR-T Warning; New Blincyto Indication; Good News in Pancreatic Cancer

Cancer research in the US is world class. With the government pulling out, its future is uncertain

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