Targeting enzymes to weaken cancer cells could supercharge prostate cancer treatment

Published Date: 14 Oct 2025

An international study has uncovered a new vulnerability in prostate cancer cells that could help improve treatment for one of the most common cancers affecting men.

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4D CT Aids Parathyroid Adenoma Localisation, Lateralisation

Multiphase '4D' CT offers reliable diagnostic accuracy for localising parathyroid adenomas when first-line nuclear medicine imaging and ultrasound yield negative or discordant results.

Increased Coffee Intake May Lower Liver Disease Risk

Higher coffee consumption is associated with better liver outcomes than no coffee consumption, a recent study finds.

Could Childhood Obesity Risk Begin Before Birth?

Emerging evidence links prenatal biology and early-life exposures to later obesity risk, suggesting that prevention may need to begin before excess weight develops.

Novonesis Expects Results From Weight-loss Drug Supplement Study in 2027

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Prepubertal T1D Onset Tied to Lower Risk for Complications

Children diagnosed with T1D before age 7 may face a lower risk for long-term chronic complications in the first 20 years post-diagnosis than those diagnosed later in childhood.

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Emerging ADC-Based Strategies in mNSCLC: Interpreting Clinical Evidence and Implications for Practice

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Bridging the Gap to CAR T-Cell Therapy for Relapsed/Refractory Multiple Myeloma: An Expert TheraTalk

Can a Betting Market Offer Hope to a Cancer Patient?

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Post-Transplant Outcomes in Hodgkin Lymphoma Improved Over Time

Improvements primarily driven by reduction in incidence of relapse

Todays Updates

Emerging ADC-Based Strategies in mNSCLC: Interpreting Clinical Evidence and Implications for Practice

Emerging ADC-Based Strategies in mNSCLC: Interpreting Clinical Evidence and Implications for Practice

Bridging the Gap to CAR T-Cell Therapy for Relapsed/Refractory Multiple Myeloma: An Expert TheraTalk

Bridging the Gap to CAR T-Cell Therapy for Relapsed/Refractory Multiple Myeloma: An Expert TheraTalk

Can a Betting Market Offer Hope to a Cancer Patient?

As we embrace the power of collective knowledge, we must remember that numbers are just numbers

Rewriting the Future of Medicine; Cancer Cost Burden; Mental Health Toll of Cancer

News, features, and commentary about cancer-related issues

Biden's Bedtime Cancer Symptom; Top Cancer Hospitals; FDA Panel to Review MCED Test

News, features, and commentary about cancer-related issues

Liposomal Chemo Combination No Better Than Standard Induction in Pediatric AML

"This specific formulation of daunorubicin and cytarabine is not the right choice," experts said

Post-Transplant Outcomes in Hodgkin Lymphoma Improved Over Time

Improvements primarily driven by reduction in incidence of relapse

Latest News

Multiphase '4D' CT offers reliable diagnostic accuracy for localising parathyroid adenomas when first-line nuclear medicine imaging and ultrasound yield negative or discordant results.

Higher coffee consumption is associated with better liver outcomes than no coffee consumption, a recent study finds.

Emerging evidence links prenatal biology and early-life exposures to later obesity risk, suggesting that prevention may need to begin before excess weight develops.

Danish biosolutions maker Novonesis expects results in the second half of 2027 from research ⁠with Novo Nordisk into whether microbiome supplements could provide additional...

Children diagnosed with T1D before age 7 may face a lower risk for long-term chronic complications in the first 20 years post-diagnosis than those diagnosed later in childhood.

Celon Pharma's experimental semaglutide product Reduzek, a generic alternative ⁠to Novo Nordisk's Wegovy and Ozempic, matched the blockbuster weight-loss ⁠drugs in an...

News All Time

Novo Begins Study to Find Lowest Effective Dose for Wegovy Pill

Danish drugmaker Novo Nordisk is testing smaller doses of its Wegovy pill in a new late-stage study to find the lowest ⁠dose that would still help patients lose weight,...

Prior GLP-1 Use Doesn’t Affect Bariatric Surgery Results

Patients who have and have not had prior GLP-1 treatment show similar levels of weight loss with bariatric surgery.

Screening for Confidence Tailors GLP-1 Care

Perceived competence — not other factors — best distinguishes weight-loss success with GLP-1 treatment.

Amylyx Drug Cuts Low Blood Sugar Episodes in Bariatric Surgery Patients in Key Trial

Amylyx Pharmaceuticals' experimental drug sharply reduced dangerously low blood sugar episodes in a late-stage trial of patients who ⁠underwent weight-loss surgery, sending...

Diabetes Drug Curbs Weight Gain in Older People With HIV

Metformin, a common diabetes drug, curbs weight gain in older people with HIV over 96 weeks, but the effect reverses after treatment stops, a trial finds.

Semaglutide and Depression: No Clear Link Found

A meta-analysis finds no significant association between use of semaglutide and risk for depression, although with limited certainty of evidence.

GI Medicine Is a ‘Fantastic Voyage’: AGA President Cryer

Gastroenterologist Byron L. Cryer, MD, discusses mentorship, NSAID research, difficult patient conversations, and why access to care remains a pressing challenge.

Swapping Soda for Diet Drinks May Not Cut T2D Risk

Swapping sugary drinks for diet drinks is linked to an increased risk for type 2 diabetes, particularly among younger adults and those of non-Dutch origin.

Low-Carb Diet Tied to Healthier Target Weight

In women with overweight or obesity, eating lower carbs is linked to a healthier target weight and lower waist circumference, body fat, and visceral fat but not to the A Body Shape Index.

CGM Metrics Can Improve Prognosis Insights Beyond A1c in T1D

In patients with T1D, certain CGM metrics can provide information on the risk for severe hypoglycemia independent of A1c and add predictive value for diabetic ketoacidosis.

Health Round: Most Air Pollution Exposure in U.S. Pregnancies Is From Wildfires, Study Says

We also share a report from cardiologists that suggests you might (or might not) want to check your waist and hip measurements, and a laboratory study with some encouraging...

Prader-Willi Experts Flag Safety Risks Linked to Rare Disease Drug

Experts in Prader-Willi Syndrome on Tuesday raised safety concerns over Neurocrine's drug Vykat XR, citing serious adverse events reported ⁠in patients with the rare genetic...

Weekly Somapacitan Effective and Safe in Turner Syndrome

Once-weekly somapacitan is as effective as daily growth hormone in promoting linear growth among treatment-naive girls with Turner syndrome, offering a suitable alternative treatment.

Role-Play as Patients Helps Docs Manage Diabetes Better

A 1-week, on-site role-play-based program in which physicians simulate patient experiences leads to better A1c control in patients with type 2 diabetes at 6 and 12 months.

Duration and Age Tied to Different Complication Risks in T1D

In patients with childhood onset T1D, a longer diabetes duration is mainly linked to a higher risk for retinopathy, and older age more strongly predicts albuminuria after over 30 years of follow up.

Low-Carb Diets: Modest Wins for Weight, Blood Sugar

Cutting carbs may help adults with overweight or obesity achieve modest weight loss and improve some metabolic markers, but the benefits appear limited and don’t increase with stricter restriction.

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