Multiple motor regions of the brain are underactive during lower limb movements in Parkinson's patients, according to a study.

Published Date: 26 Apr 2023

Parkinson's disease is a prevalent neurodegenerative condition that impairs movement. A person's gait and balance are eventually affected by the disease, which frequently starts with minor hand tremors.

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Depression is one of the most widespread mental health disorders worldwide, characterized by persistent feelings of sadness, a loss of interest in everyday activities, dysregulated sleep or eating patterns and other impairments. ...

A University of Alberta research team has discovered a new function for brain molecules known as gangliosides, offering potential new targets for the treatment of Huntington's and other genetic neurological diseases.

Aggression and self-harm often co-occur in individuals with a history of early-life trauma—a connection that has largely been documented by self-reporting in research and clinical settings. Adding to this connection, individuals ...

Abnormal repetitive behaviors in mice are strongly linked to multiple biomarkers of oxidative stress, which occurs when antioxidants cannot counteract the effects of harmful molecules in the body, according to a study published ...

Levels of certain biomarkers in the blood are associated with symptom severity during recovery from concussion in adolescents—with some significant differences between male and female patients, reports a study in the Journal ...

Caricature artists exaggerate distinctive features of an individual, deepening a cleft chin or multiplying freckles. Yale researchers have now applied a similar approach to maps of neural connections, emphasizing individual ...

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Study pinpoints source of free radicals in the brain that may fuel dementia

Free radicals generated at a specific site in non-neuronal brain cells called astrocytes may promote dementia, according to a Weill Cornell Medicine study. These findings, published in Nature Metabolism, demonstrated that ...

Significant variations in survival times of early onset dementia by clinical subtype

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Personalized care can ease Parkinson's pain

Every 27 minutes, someone in Australia is diagnosed with Parkinson's disease. Best known for its tremors, movement and balance issues, it also brings another, often overlooked burden—persistent pain.

Detailed map of the developing human brain opens new pathways for Parkinson's treatment

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People with major depressive disorder or schizophrenia have been found to have lower levels of the synaptic protein "SNAP-25" in their cerebrospinal fluid, according a study by University Medicine Halle that included more ...

Massive database maps links between brain development and mental health

A new large-scale, open data resource from the Perelman School of Medicine and collaborators helps researchers link brain development with mental health disorders.

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Exploring the relationship between sleep and diet

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Small brain region linked to schizophrenia risk through unique gene changes

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Families pay thousands for an unproven autism treatment: Researchers say we need ethical guidelines

Over the last decade, clinics have popped up across Southern California and beyond advertising something called magnetic e-resonance therapy, or MERT, as a therapy for autism.

Even modest amounts of physical activity may slow Alzheimer's disease among at-risk older adults

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Imaging study shows how brains go off-track in rare childhood disorder

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'Frazzled' fruit flies help unravel how neural circuits stay wired

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People with autism spectrum disorders commonly have difficulty processing sensory information, which can make busy, bright or loud settings—such as schools, airports and restaurants—stressful or even painful. The neurological ...

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