Multiple motor regions of the brain are underactive during lower limb movements in Parkinson's patients, according to a study.

Published Date: 26 Apr 2023

Parkinson's disease is a prevalent neurodegenerative condition that impairs movement. A person's gait and balance are eventually affected by the disease, which frequently starts with minor hand tremors.

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Research in mice reveals brain cells that drive—and prevent—anxiety

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LSD microdosing reduces depression scores without major side effects, clinical trial finds

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Chemical compound holds potential against Alzheimer's disease

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Making informed decisions and managing regret after prostate cancer treatment

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Latest News

NMNAT2 is a key protein required for axon integrity whose rapid depletion following axon injury triggers Wallerian degeneration. The molecular mechanism controlling NMNAT2 turnover in neurons has not been fully understood. ...

Anxiety disorders are some of the most common mental health conditions in America, affecting about one in five people nationwide. But much remains unknown about the roots of anxiety in the brain. Now, research at the University ...

University of Auckland researchers report that an 8-week, twice-weekly LSD microdosing regimen for major depressive disorder was feasible and well-tolerated, with Montgomery-Åsberg Depression Rating Scale (MADRS) scores ...

Neurodegenerative diseases, such as Alzheimer's disease and dementia, are medical conditions that entail the progressive loss of neurons and a decline in brain function. Past studies have found a link between these diseases ...

Mayo Clinic researchers have developed a new tool that can estimate a person's risk of developing memory and thinking problems associated with Alzheimer's disease years before symptoms appear.

A team of researchers at the Federal University of ABC (UFABC) in Brazil has developed a new chemical compound with the potential to treat Alzheimer's disease. The research involved computer simulations (in silico), cell ...

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Preventing brain damage in premature babies: Lab-grown brain model reveals new hope

A treatment that could protect premature babies from brain damage showed promise in a recent study in Sweden. Using a first-of-its-kind prenatal brain model created with human cells, researchers observed new details about ...

Removing toxic proteins before they can damage motor neurons

University of Wollongong (UOW) scientists have developed a breakthrough therapy that clears toxic proteins from nerve cells—a discovery that advances the work of the late Professor Justin Yerbury and could transform the ...

Anxiety disorders tied to low levels of an essential nutrient in the brain

People with anxiety disorders have lower levels of choline in their brains, according to research from UC Davis Health.

Controlled oxygen reduction can boost brainpower without moving a muscle

It's well known that exercise is good for your brain. For years, scientists have shown even a single session of heart-pumping activity can sharpen executive function—the mental skills we use to plan, focus attention, remember ...

Genetic technique may enable precision treatment of pediatric brain tumors

The malignant pediatric brain tumor medulloblastoma is driven by proteins deep within the cancer cells, for which there are often no effective drugs available. Researchers at Uppsala University have identified a new genetic ...

Exploring how the maternal bond affects social processing in babies

In a new JNeurosci paper, Sarah Jessen and colleagues, from the University of Lübeck, explored how infants track their mothers' voices compared to unfamiliar voices. The researchers also explored whether this vocal processing ...

NAD⁺ restores memory in Alzheimer's disease models by correcting RNA errors

Alzheimer's disease (AD), the leading cause of dementia, affects nearly 40 million individuals globally, resulting in a gradual loss of memory and independence. Despite extensive research over the past decades, no treatments ...

Review links air pollution and Alzheimer's and offers a preventive plan

A new peer-reviewed article published in the Journal of Alzheimer's Disease, by the Alzheimer's Research and Prevention Foundation, reveals compelling evidence that air pollution and climate stress are major (modifiable) ...

Zero-cost, AI-driven digital detection identifies Alzheimer's without additional clinician time

Few primary care practices are designed for the timely detection of Alzheimer's disease and related dementias. The limited time that primary care clinicians are able to spend with patients, the need to focus on the health ...

New method to track progression of Alzheimer's, related dementias based on metabolic, vascular brain changes

Researchers from the Indiana University School of Medicine have developed a highly sensitive diagnostic that predicts a person's stage of dementia based on neurovascular and metabolic changes. They recently published their ...

Tylenol during pregnancy: No strong evidence ties use to autism or ADHD risk

Existing evidence does not clearly link paracetamol (acetaminophen) use during pregnancy with autism or ADHD in children, finds an in-depth evidence review published by The BMJ today, in direct response to recent announcements ...

Just 3,000 steps a day linked to lower Alzheimer's risk in older adults

A new study suggests that even low levels of physical activity could protect the brain from Alzheimer's disease—but not in the way scientists expected.

Time change: What neuroscience reveals about our internal clock

It's well-known that neural circuits help synchronize our biological clock with the day-night cycle. But just how exactly do those circuits develop, and can better understanding the process help, for example, in treating ...

Positive rate for benign paroxysmal positional vertigo higher in morning than evening

For benign paroxysmal positional vertigo (BPPV), the overall positive rate for positional tests is significantly higher in the morning than in the evening, according to a study published online Oct. 6 in Frontiers in Neurology.

Coordinated brain network activity during emotional arousal may explain vivid, lasting memories

Past psychology studies suggest that people tend to remember emotional events, such as their wedding, the birth of a child or traumatic experiences, more vividly than neutral events, such as a routine professional meeting. ...

Gadolinium-enhanced MRI improves accuracy for Meniere disease, delayed endolymphatic hydrops

Gadolinium-enhanced delayed inner ear magnetic resonance imaging (MRI) improves diagnostic accuracy for Meniere disease (MD) and delayed endolymphatic hydrops (DEH), according to a study published online Oct. 7 in Science ...

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