Centessa to Advance Orexin Agent ORX750 to Phase 2 Studies Following Positive Interim Data

Published Date: 19 Sep 2024

In the phase 1 trial, the 2.5 mg dose of ORX750 significantly improved wakefulness, restoring normal sleep latency to 32 minutes compared to placebo.

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Ocular motor cranial neuropathy is associated with an increased risk for Parkinson’s disease, a new study shows.

Traumatic brain injury is bidirectionally associated with the incidence of stroke, dementia, epilepsy, and Parkinson’s disease, a retrospective study shows.

Targeted interventions, especially avatar therapy, are associated with less severe auditory hallucinations in patients with schizophrenia, a new meta-analysis shows.

In a small feasibility study, a novel adaptive DBS system synchronized with the walking cycle has been shown to reduce the risk for falls among patients with Parkinson’s disease.

Electroconvulsive therapy (ECT) is associated with longer time to hospital readmission or suicide compared to non-ECT treatment in patients with schizophrenia, a study shows.

Comorbid primary sleep disorders are tied to higher risk for sudden unexpected death, all-cause mortality, and accidents in patients with epilepsy, a new study finds.

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