Optimizing UC Therapy in the Presence of Comorbidities

Published Date: 21 May 2026

Dr Corey Siegel discusses the importance of individualized therapy selection for ulcerative colitis in the presence of comorbidities.

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Molecular testing for metastatic prostate cancer with next generation sequencing (NGS) is standard for the evaluation for targetable pathogenic variants.

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TKI Discontinuation Feasible After ALL Treatment

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For patients with early-stage, inoperable lung cancer, adding atezolizumab to standard radiotherapy boosts toxicity, not survival.

Todays Updates

UK Lawmakers Reject Bid to Legalise Assisted Dying

British lawmakers rejected on Friday a proposal to legalise assisted dying for terminally ill people, dealing a major setback to campaigners and bringing the latest effort...

Liberalized Cannabis Policies May Increase Substance Use

In a global review, legalization was associated with increased cannabis use and related emergency department visits, with potential decreases in the use of alcohol and tobacco.

Tissue-Free ctDNA Predicts Recurrence in Early Breast Cancer

Researchers analyzed plasma samples collected from 313 patients with early breast cancer approximately 2 years after they had completed adjuvant chemotherapy.

Can Response-Adapted Surgery Improve Outcomes in HNSCC?

Patients who respond to neoadjuvant immunochemotherapy may be able to undergo less extensive surgery, with high rates of disease control and organ preservation.

TKI Discontinuation Feasible After ALL Treatment

In patients with first- or second-line Philadelphia-positive B-cell acute lymphoblastic leukemia, favorable outcomes are observed with discontinuation of ponatinib.

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Molecular testing for metastatic prostate cancer with next generation sequencing (NGS) is standard for the evaluation for targetable pathogenic variants.

What role do diet, obesity, the microbiome, and screening play in early-onset colorectal cancer? Dr Benjamin Levy and Dr Aasma Shaukat discuss the latest evidence.

Rare squamous transformation in metastatic prostate cancer caused disease progression despite suppressed PSA, found only through re-biopsy.

No dose of alcohol is risk-free, and none protects the heart. It's time to counsel patients on drinking less rather than where the line sits.

A woman receiving ruxolitinib for polycythemia vera developed disseminated tuberculosis despite a negative IGRA, highlighting the limits of screening.

From nutrition screening to IBD monitoring, AI shows promise in pediatric gastroenterology — yet experts stress pediatric validation is essential.

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Teen With a Slowly Enlarging Annular Hyperkeratotic Papule

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Early Breast Cancer: Time to Act on Molecular Resistance?

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Punch Biopsy Techniques Every PCP Should Know

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A PCP’s Guide to Tangential Shave Biopsy

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Four Signs You Should Biopsy a Skin Lesion, Not Freeze It

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BRCA Testing Shifts From Late Data to Urgent Priority

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Wet Age-Related Macular Degeneration Updates From ASRS 2026

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Stop Assuming Every Thick, Yellow Nail Is Fungus

Treating toenail fungus without confirming the diagnosis is a common mistake. Here's how to confirm it, treat it, and know what to expect.

Trust Me — I'm a Podcaster

Public trust in institutions has waned but patients trust their personal doctors. Clinicians can be influencers without TikTok or a podcast writes this podcasting cardiologist.

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