The data show that Regorafenib is equivalent to TAS-102 in metastatic CRC.

Published Date: 08 Mar 2023

A real-world comparison showed similar overall survival in patients with refractory metastatic CRC treated with regorafenib or trifluridine/tipiracil (TAS-102).

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Demographic disparities found in uptake of colorectal cancer screenings

Colorectal cancer (CRC) screening is considered one of the most effective and successful tools to protect public health: Screening has been found to significantly reduce the incidence of CRC through the removal of precancerous ...

1 in 10 people without celiac disease or wheat allergy report sensitivity to gluten or wheat, finds study

Around one in ten people worldwide report gastrointestinal and other symptoms such as fatigue and headache after eating foods containing gluten or wheat despite not having a diagnosis of either celiac disease or wheat allergy, ...

How bacteria that cause inflammatory colitis outmaneuver our body's defenses

Bacteria use multiple defense mechanisms to survive in the host body. Shigella bacteria that cause colitis disable multiple host defense pathways using three specialized effector proteins, as reported by researchers from ...

Protecting the gut after stem cell transplantation: New evidence uncovered for potential of microbiome-based therapies

Patients receiving intensive cancer treatments—such as radiation or stem cell transplantation—often suffer from severe damage to the intestinal lining. This not only causes pain and complications but also worsens long-term ...

New study highlights need for coordinated approach to stomach cancer screening and prevention

Stomach cancer, or gastric cancer, is the third leading cause of cancer deaths worldwide, largely because most individuals are not diagnosed until after the cancer has progressed to a late stage.

A Mediterranean diet could be the place to start when tackling IBS

A randomized clinical trial has found that the Mediterranean diet is superior to traditional diet advice in managing irritable bowel syndrome (IBS) symptoms, suggesting that it could be considered a viable first-line dietary ...

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Molecular profiling of renal medullary carcinoma identifies TROP2 as a promising therapeutic target

Researchers at The University of Texas MD Anderson Cancer Center, in collaboration with BostonGene, conducted the largest and most comprehensive molecular analysis of renal medullary carcinoma (RMC), a rare and aggressive ...

FDA approves Blenrep for relapsed or refractory multiple myeloma

The U.S. Food and Drug Administration approved Blenrep (belantamab mafodotin-blmf) in combination with bortezomib and dexamethasone for the treatment of adult patients with relapsed or refractory multiple myeloma.

Todays Updates

Molecular profiling of renal medullary carcinoma identifies TROP2 as a promising therapeutic target

Researchers at The University of Texas MD Anderson Cancer Center, in collaboration with BostonGene, conducted the largest and most comprehensive molecular analysis of renal medullary carcinoma (RMC), a rare and aggressive ...

FDA approves Blenrep for relapsed or refractory multiple myeloma

The U.S. Food and Drug Administration approved Blenrep (belantamab mafodotin-blmf) in combination with bortezomib and dexamethasone for the treatment of adult patients with relapsed or refractory multiple myeloma.

Latest News

Colorectal cancer (CRC) screening is considered one of the most effective and successful tools to protect public health: Screening has been found to significantly reduce the incidence of CRC through the removal of precancerous ...

Around one in ten people worldwide report gastrointestinal and other symptoms such as fatigue and headache after eating foods containing gluten or wheat despite not having a diagnosis of either celiac disease or wheat allergy, ...

Bacteria use multiple defense mechanisms to survive in the host body. Shigella bacteria that cause colitis disable multiple host defense pathways using three specialized effector proteins, as reported by researchers from ...

Patients receiving intensive cancer treatments—such as radiation or stem cell transplantation—often suffer from severe damage to the intestinal lining. This not only causes pain and complications but also worsens long-term ...

Stomach cancer, or gastric cancer, is the third leading cause of cancer deaths worldwide, largely because most individuals are not diagnosed until after the cancer has progressed to a late stage.

A randomized clinical trial has found that the Mediterranean diet is superior to traditional diet advice in managing irritable bowel syndrome (IBS) symptoms, suggesting that it could be considered a viable first-line dietary ...

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AI tool beats humans at detecting parasites in stool samples

Scientists at ARUP Laboratories have developed an artificial intelligence (AI) tool that detects intestinal parasites in stool samples more quickly and accurately than traditional methods, potentially transforming how labs ...

Alterations in gut microbiota linked to health-related quality of life outcomes in IBD

For patients with inflammatory bowel disease (IBD), alterations in gut microbiota are associated with health-related quality of life (HRQoL) outcomes, according to a study published online Sept. 29 in The American Journal ...

A year of dieting with non-sugar sweeteners shows weight loss can stay lost

Researchers at Maastricht University and the University of Copenhagen report that incorporating sweeteners and sweetness enhancers within a healthy, sugar-reduced diet supported one-year weight loss maintenance and coincided ...

Preventing malnutrition in people with blood cancer

Malnutrition is a common but difficult-to-manage complication for people with cancer, especially those treated with intensive chemotherapy. Now, new research from the University of Adelaide has delivered new insights into ...

Scientists develop a way to track donor bacteria after fecal microbiota transplants

Researchers at the Icahn School of Medicine at Mount Sinai and their collaborators have developed a new technology to track beneficial bacteria after fecal microbiota transplants (FMT). The approach provides a detailed view ...

Eat kiwifruit for constipation, new guidelines say. But ditch the high-fiber diet

New guidelines on what to eat and drink if you have chronic (long-term) constipation have been making news in recent days.

Experts advise better performance measures relevant to internal medicine for colorectal cancer screening

Colorectal cancer is the second leading cause of cancer-related deaths for males and females. Screening for colorectal cancer is an effective strategy to reduce morbidity and mortality. The evidence-based guidance statement ...

Digestive issues more common during perimenopause and menopause, study finds

Digestive health issues are highly prevalent among perimenopausal and menopausal women, with many reporting the onset or exacerbation of symptoms during this life stage. Despite symptom burden, formal diagnoses and effective ...

Experts urge risk-based monitoring as Barrett's esophagus care moves beyond one-size-fits-all

The American Gastroenterological Association (AGA) today released a new clinical practice guideline on the surveillance of Barrett's esophagus, the only known precursor to esophageal cancer (adenocarcinoma), a highly lethal ...

Fecal microbiota transplant may help patients with IBS and depressive symptoms

A meta-analysis of randomized trials suggests fecal microbiota transplantation can ease depressive symptoms, with stronger effects reported for endoscopic or enema delivery, according to researchers at the Department of Nursing, ...

Gut microbiome affects alcohol preference by influencing brain's reward system

Researchers at Tufts University School of Medicine and Tufts Graduate School of Biomedical Sciences have found a surprising connection between a fungus associated with alcohol use disorder and the brain's dopamine reward ...

Comparing behavioral approaches for irritable bowel syndrome

Researchers led by Wake Forest University School of Medicine and Atrium Health have judged the certainty of evidence on behavioral therapies for irritable bowel syndrome to be low to very low as many published trials show ...

Scientists identify markers of key stem cell populations driving colorectal cancer formation

Researchers from A*STAR Institute of Molecular and Cell Biology (A*STAR IMCB) have identified markers of two critical stem cell populations that drive colorectal cancer formation.

Challenges seen in diagnosing UTI in children with neurogenic bladder

Most children with neurogenic bladder (NGB) and diagnosed with febrile urinary tract infection (UTI) in the emergency department (ED) did not meet a commonly recommended definition for UTI, according to a study published ...

New insights into the role of stellate cells and blood vessels in the aging pancreas

As age increases, the pancreas changes, which increases the risk of metabolic diseases such as type 2 diabetes, digestive disorders, and also cancer. Researchers at the German Institute of Human Nutrition Potsdam-Rehbruecke ...

Research paves the way for potential anti-ulcer vaccine

Since ancient times, it was thought that painful stomach ulcers were caused by eating spicy foods or having an unhealthy diet. But since then, researchers have found that Helicobacter pylori—a common bacterium found in ...

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