Opthea Announces Termination of ShORe and COAST Trials of Sozinibercept

Published Date: 11 Apr 2025

The treatment for wet age-related macular degeneration failed to achieve its primary endpoint in both trials.

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The antibody drug conjugate was approved by the FDA for certain patients with triple-negative breast cancer.

Todays Updates

EMA Backs Breast Cancer SERD After FDA No Vote

The recommendation follows phase 3 data showing longer progression-free survival when patients switched to camizestrant plus a CDK4/6 inhibitor.

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The antibody drug conjugate was approved by the FDA for certain patients with triple-negative breast cancer.

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A treatment that targets dysfunctional photoreceptors regardless of the underlying genetic mutation leads to improved functional vision in advanced severe vision loss.

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Navigating Sustained Delivery in DME: An Interactive Clinical Decision-Making Simulation

Beyond Intravitreal Injections: Advancing Retinal Vascular Disease Care With Sustained Delivery Therapies

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One GLP-1 Drug May Be Better Than Rivals for Glaucoma Risk

But it's not time to prescribe tirzepatide outside current indications, expert says

Color Blindness and Bladder Cancer: A Bad Combination for Survival?

Study suggests inability to identify blood in urine may delay diagnosis and reduce survival

Cardiovascular Risk Score Shows Value in Predicting Future Eye Disease

The score is commonly calculated in primary care

People, Faces Appeared Smaller Than Usual in Patient's Rare Case

63-year-old had an atypical cause of Alice in Wonderland Syndrome

Contaminated Water Blamed for 10 Deaths; FDA Rejections; Mammograms for Heart Risks?

Health news and commentary gathered by MedPage Today staff

FDA OKs More Eye Drops That Can Replace Reading Glasses

Once-daily carbachol/brimonidine tartrate significantly improves aging-related vision loss

Sleeping With Two Pillows May Raise Internal Eye Pressure in Glaucoma

Stacked pillows alter the neck position and may compress the jugular, researchers suggest

Teen Boy Grows a Tooth Between Eyelid and Eyebrow

The 16-year-old underwent surgery to remove an ectopic canine tooth in left eye's superior orbit

Study Adds Fuel to the Debate Over Cataract Surgery and Wet AMD

Earlier concerns about surgery accelerating AMD progression likely overstated, researcher says

Hospital Had Ties to Epstein; Naked Knifeman at Eye Doctor; Health Department Probed

Health news and commentary gathered by MedPage Today staff

Some Blind Fans to Experience Super Bowl With Tactile Device That Tracks Ball

About 10 blind and low-vision fans will have an opportunity to use the technology

CDC Study Warns of Vision-Threatening Eye Infections After Laser Surgery

Three patients at New York City clinic developed fungal keratitis caused by a mold

Dry Eye: Handmaiden to Many Autoimmune Conditions, Not Just Sjogren's Disease

Taiwanese study puts numbers to common but poorly studied phenomenon

Retinopathy Risk With Long-Term HCQ Treatment Detailed in Meta-Analysis

Eye damage remains uncommon after 15 years, but certain factors increase the risk

Glaucoma Checks in Primary Care; Wastewater to Screen for Colorectal Cancer

Also in TTHealthWatch: new cholesterol management guidelines

Wegovy May Carry Highest Risk of Blinding Condition Among GLP-1 Drugs

First evidence of formulation-specific difference, significantly higher in men than women

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