Higher Crohn's disease rates with vedolizumab: a study

Published Date: 13 Mar 2023

The study results may prompt doctors to choose vedolizumab over anti-TNF therapy as the first-line treatment for Crohn's disease.

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Quizartinib Benefit in AML Limited to FLT3-Mutated Subgroup

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Older adults with lower gastrointestinal bleeding present with more severe disease and substantially higher 30-day mortality—yet most deaths stem not from bleeding itself, but from decompensation of underlying chronic conditions.

The vaccine spurs a lasting immune response in people at a high risk for pancreatic cancer. Whether it staves off the disease remains to be seen.

Researchers examine 4-year outcomes of the phase 3 TOPAZ-1 study.

PEG 1 L beats ‘more-is-better’ pre-colonoscopy regimens, demonstrating more high-quality cleansing and greater tolerability than 2-L and 4-L formulations.

Admitted for pyelonephritis, but his diagnostic journey is just beginning

A cautionary tale of gastroparesis-related aspiration in NPO patient with no other risk factors

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Perfusion Preservation Strategy Boosts Liver Transplant Outcomes

Portal-venous hypothermic oxygenated perfusion reduced incidence of early allograft dysfunction

GLP-1s and Chronic Pancreatitis; Hypoglycemia After Bowel Prep; Lower GI Bleeding

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Novel Hep B Drug Delivers Functional Cures in Late-Stage Trials

Findings "will change the landscape" of treatment, researcher says

TIPS Was Tops for Refractory Hydrothorax in Cirrhosis

Majority of patients who received TIPS had a complete clinical response

Enhanced MRI Tops Ultrasound in Catching Early Liver Cancer

MRI approach also led to fewer false referrals

Multicancer Early Detection Test Fails to Reduce Cancers Detected at Late Stages

However, an increase in the detection of stage I/II cancers was observed

'A Grand Slam' in Pancreatic Cancer: Novel Pill Doubles Survival

RASolute 302 findings herald a new standard of care in previously treated patients

Albumin 5% Cut Mortality Rates in Sudden Liver Failure With Other Organ Failure

Treatment may be an effective bridge to transplantation for acute-on-chronic liver failure

Saroglitazar Boosts Response Rates in Primary Biliary Cholangitis

More than half of patients saw a biochemical response by 1 year with the novel oral agent

Targeted Combo Boosts PFS in BRAF-Mutant Metastatic Colorectal Cancer

Adding encorafenib and cetuximab to chemotherapy backbone also prolonged overall survival

Non-Operative Treatment for CRC May Include Observation After Complete Response

No difference in disease-free, overall survival compared with 3 years of maintenance therapy

Adding Immunotherapy-Based Combo Boosts PFS in Unresectable Liver Cancer

But is the higher incidence of grade 3/4 adverse events "a worthwhile price to pay?" expert asks

Large Study Links GLP-1s to Lower Risk of Multiple Cancers

Patients taking the drugs for obesity had a 41% lower risk of related cancers

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News and commentary from the world of gastroenterology and hepatology

NICU Babies More Likely to Miss Rotavirus Vax

Study shows impact of guidelines' strict upper age limit and suggestion of delay until discharge

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