Higher Crohn's disease rates with vedolizumab: a study

Published Date: 13 Mar 2023

The study results may prompt doctors to choose vedolizumab over anti-TNF therapy as the first-line treatment for Crohn's disease.

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New guidance says continuing surveillance should factor in comorbidities, life expectancy, risks vs benefits, and surgical tolerance levels, as well as patient preferences.

Relapse Uncommon After Surgery for Appendiceal Cancer

But the risk of relapse after resection of localized appendiceal adenocarcinoma varies by histologic subtype, with potential implications for risk assessment and adjuvant treatment.

Bowel Cancer Under 50: Rethinking Screening and Diagnosis

Australia has the highest rate of bowel cancer in the world among patients younger than 50 years, and encouraging more people to screen could be key in tackling this problem.

Explainer: India's Unprecedented Food Safety Push

India is witnessing an unprecedented food safety crackdown, with regulators forcing many restaurants to suspend operations and pushing for front-of-pack warning labels.

MRCP Detects PSC in 10% of New IBD Cases

A prospective Danish study reveals that radiological primary sclerosing cholangitis affects nearly 10% of patients with newly diagnosed inflammatory bowel disease.

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UK Lawmakers Reject Bid to Legalise Assisted Dying

British lawmakers rejected on Friday a proposal to legalise assisted dying for terminally ill people, dealing a major setback to campaigners and bringing the latest effort...

Liberalized Cannabis Policies May Increase Substance Use

In a global review, legalization was associated with increased cannabis use and related emergency department visits, with potential decreases in the use of alcohol and tobacco.

Tissue-Free ctDNA Predicts Recurrence in Early Breast Cancer

Researchers analyzed plasma samples collected from 313 patients with early breast cancer approximately 2 years after they had completed adjuvant chemotherapy.

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Patients who respond to neoadjuvant immunochemotherapy may be able to undergo less extensive surgery, with high rates of disease control and organ preservation.

TKI Discontinuation Feasible After ALL Treatment

In patients with first- or second-line Philadelphia-positive B-cell acute lymphoblastic leukemia, favorable outcomes are observed with discontinuation of ponatinib.

SBRT Plus Atezolizumab Shows No Benefit in Inoperable NSCLC

For patients with early-stage, inoperable lung cancer, adding atezolizumab to standard radiotherapy boosts toxicity, not survival.

Todays Updates

UK Lawmakers Reject Bid to Legalise Assisted Dying

British lawmakers rejected on Friday a proposal to legalise assisted dying for terminally ill people, dealing a major setback to campaigners and bringing the latest effort...

Liberalized Cannabis Policies May Increase Substance Use

In a global review, legalization was associated with increased cannabis use and related emergency department visits, with potential decreases in the use of alcohol and tobacco.

Tissue-Free ctDNA Predicts Recurrence in Early Breast Cancer

Researchers analyzed plasma samples collected from 313 patients with early breast cancer approximately 2 years after they had completed adjuvant chemotherapy.

Can Response-Adapted Surgery Improve Outcomes in HNSCC?

Patients who respond to neoadjuvant immunochemotherapy may be able to undergo less extensive surgery, with high rates of disease control and organ preservation.

TKI Discontinuation Feasible After ALL Treatment

In patients with first- or second-line Philadelphia-positive B-cell acute lymphoblastic leukemia, favorable outcomes are observed with discontinuation of ponatinib.

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For patients with early-stage, inoperable lung cancer, adding atezolizumab to standard radiotherapy boosts toxicity, not survival.

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New guidance says continuing surveillance should factor in comorbidities, life expectancy, risks vs benefits, and surgical tolerance levels, as well as patient preferences.

But the risk of relapse after resection of localized appendiceal adenocarcinoma varies by histologic subtype, with potential implications for risk assessment and adjuvant treatment.

Australia has the highest rate of bowel cancer in the world among patients younger than 50 years, and encouraging more people to screen could be key in tackling this problem.

India is witnessing an unprecedented food safety crackdown, with regulators forcing many restaurants to suspend operations and pushing for front-of-pack warning labels.

A prospective Danish study reveals that radiological primary sclerosing cholangitis affects nearly 10% of patients with newly diagnosed inflammatory bowel disease.

Two Trop-2-directed ADCs now hold overlapping first-line TNBC indications with sharply different toxicity profiles. Here's how PD-L1 status and safety data should guide the choice.

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U.S. Registry Data Confirm Liver Risk With Controversial Vasculitis Drug

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From Testing to Treatment: Navigating HER2-Testing and Clinical Evidence Across Solid Tumors

Paving the Way to Functional Cure: Integrating Therapeutic Advances and Latest Guidelines Into Care for People Living With Hepatitis B

Paving the Way to Functional Cure: Integrating Therapeutic Advances and Latest Guidelines Into Care for People Living With Hepatitis B

Optimizing Treatment Access and Outcomes for Patients With Eosinophilic Esophagitis: A Regional Workshop Series Aligning Payer and Clinician Approaches

Optimizing Treatment Access and Outcomes for Patients With Eosinophilic Esophagitis: A Regional Workshop Series Aligning Payer and Clinician Approaches

CDC Director Nominee Pressed on Vaccines at Senate Hearing

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News and commentary from the world of gastroenterology and hepatology

One Surgical Approach May Be Better for Complex Gallbladder Disease

Robotic cholecystectomy tied to reduced adverse outcomes over laparoscopic approach

You've Heard of Cyclospora. What Other Parasites Can You Catch From Food?

Experts describe some of the most common protozoa and worms

Iceberg Blamed in Diarrhea Outbreak; Masking Urged in Cities; DEA's Ketamine Probes

Health news and commentary gathered by MedPage Today staff

What's the Best Way to Test for Cyclospora Infection?

Microscopy and DNA tests are both viable, but sensitivity, cost, and availability vary

930 Dead in Outbreak; FDA Backtracks on Iceberg Lettuce; Chronic Cough Drug Fizzles

Health news and commentary gathered by MedPage Today staff

Novel Drug Shows Promise in Crohn's, Ulcerative Colitis

Duvakitug may be suitable for patients previously treated with advanced therapy

Lettuce Supplier Still the Focus in Cyclospora Outbreak, Despite Faulty Test Result

FDA says its investigation and outbreak data continue to point to Taylor Farms' iceberg lettuce

Inside the Intestinal Crypt: Untold Stories of Cyclospora

There's still much to learn about the parasite's past, present, and future

Singing for Chronic Belching; Excess Cancers in Crohn's; Dual Agonist for Liver Fat

News and commentary from the world of gastroenterology and hepatology

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