Higher Crohn's disease rates with vedolizumab: a study

Published Date: 13 Mar 2023

The study results may prompt doctors to choose vedolizumab over anti-TNF therapy as the first-line treatment for Crohn's disease.

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Extent of Family History Not Tied to Pancreatic Cancer Risk

The number of family relatives, first-degree or not, who have pancreatic cancer does not appear to affect the risk for intermediate lesions.

Two Studies Contrast Therapies for Liver Disease

One study compared cost-effectiveness between treatments, the other mortality rates and other long-term outcomes for GLP1-s versus SGLT2 inhibitors.

Mirum's Rare Liver Disease Drug Meets Main Goal in Mid-stage Study

Mirum Pharmaceuticals said on Monday its experimental drug, volixibat, met the main ⁠goal of a mid-stage study by reducing severe itching or pruritus in patients with ⁠a...

Trump Administration Appeals Judge's Order Upending Kennedy's Vaccine Policies

The Trump administration on Wednesday appealed a federal judge's ruling blocking key elements of Health Secretary Robert F. Kennedy Jr.'s push to reshape U.S. vaccine...

Next-Gen Sequencing Detects Neoplastic Bile Duct Strictures

DNA/RNA-based next-generation sequencing allows earlier diagnosis of neoplastic bile duct strictures, a prospective multicenter real-time study finds.

Drug-Resistant Salmonella Surfaces Risk of Backyard Poultry

Expert highlights need for better surveillance and smart antibiotic use to prevent future outbreaks.

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Most NMIBC Recurrences Seen in BCG-Exposed Patients

A large real-world study examines outcomes and treatment patterns among patients with non-muscle-invasive bladder cancer treated with BCG.

Todays Updates

Most NMIBC Recurrences Seen in BCG-Exposed Patients

A large real-world study examines outcomes and treatment patterns among patients with non-muscle-invasive bladder cancer treated with BCG.

Latest News

The number of family relatives, first-degree or not, who have pancreatic cancer does not appear to affect the risk for intermediate lesions.

One study compared cost-effectiveness between treatments, the other mortality rates and other long-term outcomes for GLP1-s versus SGLT2 inhibitors.

Mirum Pharmaceuticals said on Monday its experimental drug, volixibat, met the main ⁠goal of a mid-stage study by reducing severe itching or pruritus in patients with ⁠a...

The Trump administration on Wednesday appealed a federal judge's ruling blocking key elements of Health Secretary Robert F. Kennedy Jr.'s push to reshape U.S. vaccine...

DNA/RNA-based next-generation sequencing allows earlier diagnosis of neoplastic bile duct strictures, a prospective multicenter real-time study finds.

Expert highlights need for better surveillance and smart antibiotic use to prevent future outbreaks.

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Sexual Dysfunction in Digestive Diseases Often Missed

Digestive diseases and treatments may affect sexual function; however, clinicians address these concerns in a minority of patients despite unmet needs.

Celiac Disease Symptoms Vary by Race and Ethnicity

Race- and ethnicity-based disparities in symptom presentation and comorbidity patterns exist among patients with celiac disease.

Locally Advanced Rectal Cancer Responds to HER2 Therapy

Six of eight patients (75%) with HER2-positive rectal adenocarcinoma responded to trastuzumab and tucatinib plus chemotherapy, including four clinical complete responses.

Vitamin C’s Potential Use in Cancer Is Getting a Second Look

Decades after early trials seemed to close the book on vitamin C as a cancer treatment, a member of a group of determined researchers is receiving the therapy himself.

Education Gap Tied to Higher Risk for Young-Onset CRC Death

Researchers analyze trends in colorectal cancer mortality among adults aged 25-49 years in a study spanning about three decades.

Aspirin Unlikely to Cut Colorectal Cancer Incidence

A Cochrane Review finds aspirin likely results in little to no diﬀerence in colorectal cancer incidence at a follow-up of 5 years to less than 15 years.

Tumor Genomic Testing: Too Little, Too Late

Tumor genomic testing is critical to informed treatment decisions, but researchers find that it’s used in too few patients and often too late.

High-Impact Exercise Linked to Anal Incontinence in Women

High-impact sports may increase the risk for anal incontinence, especially among women, with many cases underdiagnosed because of stigma and low awareness.

Spyre's Inflammatory Bowel Drug Shown to Reduce Disease Activity in Mid-stage Study

Spyre Therapeutics said on Monday its experimental drug showed a significant reduction in disease activity when ⁠tested in patients with ulcerative colitis in a mid-stage...

Age and Visceral Fat May Trend Together: What to Know

Why fat that surrounds organs is more dangerous continues to be studied.

Vaccination Protects Young Men From HPV-Related Cancers

HPV-related cancers — including anal, penile, and oropharyngeal — are rare in people younger than 50, but new research suggests vaccinated boys could see cancer protection in their teens and 20s.

The Intersection Between Gut and Spine Health

Emerging research is showing more and more connection between the two.

IBD Flare Prediction Improved by Psychosocial Data

Predictive models that combine patient-reported psychosocial measures with clinical data perform well in forecasting flares in patients with inflammatory bowel disease.

Heavy Drinking Tied to Young-Onset Pancreatic Cancer

A nationwide Korean cohort study of more than 6.2 million young adults found an association between heavy alcohol use and pancreatic cancer risk before age 50.

Sacral Fracture Risk After Short-Course RT for Rectal Cancer

A recent retrospective analysis assesses the incidence and risk factors for sacral fractures among patients receiving short-course radiation therapy for rectal cancer.

How Gut Bacteria Could Trigger Memory Loss as We Age

Researchers found potential links between gut bacteria and memory loss, with gut-brain connections triggering loss of memory encoding in the hippocampus.