Higher Crohn's disease rates with vedolizumab: a study

Published Date: 13 Mar 2023

The study results may prompt doctors to choose vedolizumab over anti-TNF therapy as the first-line treatment for Crohn's disease.

Read Full News

Latest News

What Pet Owners Need to Know About New World Screwworm

Screwworm, a parasitic fly whose flesh-eating larvae feed on living animals, re-entered the U.S. Southwest in June for the first time since the 1970s, posing a threat to the...

Pre-Resection MRI May Incorrectly Stage Large Rectal Polyps

A small study finds that pre-resection pelvic MRI overstages more than 40% of large rectal polyps in patients referred for endoscopic resection.

Noninvasive Magnetic Therapy Effective in Fecal Incontinence

A novel noninvasive magnetic therapy is effective, safe, and well tolerated in patients with fecal incontinence, reducing symptom burden and disease severity.

Genotype-Guided Dosing Reduces Irinotecan Toxicity

Using UGT1A1 genotype to guide irinotecan dosing curbs severe side effects in patients with impaired metabolism of the drug.

Spyre Says Bowel Disease Drug Cuts Inflammation in Mid-stage Trial

Spyre Therapeutics said on Monday its experimental bowel disease drug met the main goal ⁠of significantly reducing disease severity in a mid-stage trial.

EMA Tightens Liver Safety Checks for Rare Vasculitis Drug

The EMA has reinforced enhanced liver surveillance for a vasculitis therapy after cases of severe and sometimes fatal drug-induced liver injury and vanishing bile duct syndrome.

Todays Updates

Timely ‘Nudges’ Help Spur Talks on Patient Care Goals

Simple well-timed prompts to clinicians and patients with advanced cancer can increase conversations around care goals, but clear documentation remains a challenge.

Todays Updates

Timely ‘Nudges’ Help Spur Talks on Patient Care Goals

Simple well-timed prompts to clinicians and patients with advanced cancer can increase conversations around care goals, but clear documentation remains a challenge.

Latest News

Screwworm, a parasitic fly whose flesh-eating larvae feed on living animals, re-entered the U.S. Southwest in June for the first time since the 1970s, posing a threat to the...

A small study finds that pre-resection pelvic MRI overstages more than 40% of large rectal polyps in patients referred for endoscopic resection.

A novel noninvasive magnetic therapy is effective, safe, and well tolerated in patients with fecal incontinence, reducing symptom burden and disease severity.

Using UGT1A1 genotype to guide irinotecan dosing curbs severe side effects in patients with impaired metabolism of the drug.

Spyre Therapeutics said on Monday its experimental bowel disease drug met the main goal ⁠of significantly reducing disease severity in a mid-stage trial.

The EMA has reinforced enhanced liver surveillance for a vasculitis therapy after cases of severe and sometimes fatal drug-induced liver injury and vanishing bile duct syndrome.

News All Time

Pancreatic Cancer Testing Falls Short of Goals

Researchers conducted a cross-sectional electronic survey to see whether respondents were offered and completed germline genetic testing following a pancreatic ductal adenocarcinoma diagnosis.

Pancreatic Cysts: What’s the Actual Cancer Risk?

Pancreatic cysts are common and usually considered low risk — but even those lesions signal a significantly elevated and sustained cancer risk.

UTI Treatment Shift: Is Nitrofurantoin Coming Out on Top?

A large Spanish trial reports higher cure rates with 5-day nitrofurantoin therapy than with fosfomycin or pivmecillinam in women with uncomplicated UTIs.

Takeda Engaged in Antitrust Scheme to Delay Generic Constipation Drug, US Jury Finds

A U.S. jury on Monday found Takeda Pharmaceutical liable for causing about $885 million in damages by delaying a generic version of its constipation drug Amitiza through an...

Blood Proteins Link Poor Sleep to Increased Cancer Risk

Suboptimal sleep health, reflected in low sleep proteomic scores, is consistently associated with an increased risk for cancer, particularly gastrointestinal malignancies.

Housing Instability Tied to Lower Rates of CRC Screening

Unmet health-related social needs, especially housing instability and transportation barriers, are linked to lower rates of screening for colorectal cancer among US adults.

Olanzapine Cuts Radiation-Induced Nausea

The drug, widely used for chemotherapy-related nausea, may also be highly effective for symptoms caused by abdominal-pelvic radiotherapy.

Silent Reflux: Clinical Conundrum Solved via Proper Testing

A chronic cough without heartburn are the tell-tale signs of the condition; surgery is typically not the answer.

Barrett Esophagus Onset Occurs Decades Before Diagnosis

Molecular clock modeling suggests that the biological onset of Barrett esophagus occurs more than 20 years before the recommended screening age.

Zenocutuzumab OK’d for NRG1 Fusion+ Cholangiocarcinoma

The bispecific antibody has previously granted accelerated approval for advanced, unresectable, or metastatic non-small cell lung cancer and pancreatic adenocarcinoma harboring the gene fusions.

Sigmoidoscopy Cuts Colorectal Cancer Risk in Men

Researchers randomly assign more than 100,000 adults without CRC to receive once-only sigmoidoscopy screening or no screening between 1999 and 2001. Here’s what they find.

False Positive mt-sDNA Tests Could Flag Other Cancers

False-positive multi-target stool tests are linked to higher rates of noncolorectal aerodigestive cancers, suggesting further workup may be indicated in these patients.