Medical Journal March 8, 2023

Published Date: 10 Mar 2023

Today's top news includes: Salt-sensitive hypertension is common in women of all ages and genders...

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Metformin Fails to Improve Insulin Resistance in Type 1 Diabetes

Metformin Fails to Improve Insulin Resistance in Type 1 Diabetes

Beyond Blood Sugar: Reframing Diabetes Awareness Through the Lens of Obesity

Beyond Blood Sugar: Reframing Diabetes Awareness Through the Lens of Obesity

Semaglutide Provides Cardiorenal Benefits in CKD With or Without Diabetes

Semaglutide Provides Cardiorenal Benefits in CKD With or Without Diabetes

Novo Nordisk’s Amycretin Demonstrates Superior Weight Loss Versus Placebo

Novo Nordisk’s Amycretin Demonstrates Superior Weight Loss Versus Placebo

Investigative Amylin Agonist Eloralintide Proves Superiority to Placebo in Weight Management

Investigative Amylin Agonist Eloralintide Proves Superiority to Placebo in Weight Management

How painkillers can contribute to anemia in cancer patients

Researchers from the German Cancer Research Center and the University of Freiburg show how certain painkillers influence the iron metabolism of liver cancer cells and can thus contribute to iron deficiency and anemia in cancer ...

Todays Updates

Merck’s Novel Antibody MK-2214 Receives FDA Fast-Track Designation Following Phase 1 Results Louie Pasculli

Merck's MK-2214 shows promise in early Alzheimer’s trials, earning FDA fast-track status for its safety and potential efficacy in slowing disease progression.

Dravet Syndrome Medication Stiripentol Effective in Real World Settings Across Various Patient Profiles Marco Meglio

New STIRUS data unveiled at AES 2025 demonstrate meaningful real-world reductions in seizures, status epilepticus, and healthcare needs with stiripentol in Dravet syndrome.

NBI-827104’s Phase 2 Disappointment Highlight Therapeutic Needs for Epileptic Encephalopathy With Continuous Spike-and-Wave During Sleep Marco Meglio

New findings reveal the challenges of treating pediatric epileptic encephalopathy with NBI-827104, highlighting the need for effective therapies.

5 FDA Headlines You Missed in November 2025

5 FDA Headlines You Missed in November 2025

Todays Updates

Merck’s Novel Antibody MK-2214 Receives FDA Fast-Track Designation Following Phase 1 Results Louie Pasculli

Merck's MK-2214 shows promise in early Alzheimer’s trials, earning FDA fast-track status for its safety and potential efficacy in slowing disease progression.

Dravet Syndrome Medication Stiripentol Effective in Real World Settings Across Various Patient Profiles Marco Meglio

New STIRUS data unveiled at AES 2025 demonstrate meaningful real-world reductions in seizures, status epilepticus, and healthcare needs with stiripentol in Dravet syndrome.

NBI-827104’s Phase 2 Disappointment Highlight Therapeutic Needs for Epileptic Encephalopathy With Continuous Spike-and-Wave During Sleep Marco Meglio

New findings reveal the challenges of treating pediatric epileptic encephalopathy with NBI-827104, highlighting the need for effective therapies.

5 FDA Headlines You Missed in November 2025

5 FDA Headlines You Missed in November 2025

Latest News

Metformin Fails to Improve Insulin Resistance in Type 1 Diabetes

Beyond Blood Sugar: Reframing Diabetes Awareness Through the Lens of Obesity

Semaglutide Provides Cardiorenal Benefits in CKD With or Without Diabetes

Novo Nordisk’s Amycretin Demonstrates Superior Weight Loss Versus Placebo

Investigative Amylin Agonist Eloralintide Proves Superiority to Placebo in Weight Management

Researchers from the German Cancer Research Center and the University of Freiburg show how certain painkillers influence the iron metabolism of liver cancer cells and can thus contribute to iron deficiency and anemia in cancer ...

News All Time

Could exercising while losing weight preserve your muscles and help keep them 'young'?

When we lose weight, we don't just lose body fat—we lose muscle, too.

Early-life ketone signaling may shape long-term metabolic health

In a major advance in metabolic research, scientists from National Taiwan University have discovered that ketone bodies produced naturally during the lactation period are not merely an alternative fuel, but act as powerful ...

New study identifies overlooked tool for menopause symptom relief

A new study from the Kinsey Institute at Indiana University, published in the journal Menopause, finds self-pleasure is a valuable care strategy for managing menopause symptoms, especially mood and sleep changes. Most women ...

Experimental drug protects mitochondria and prevents kidney injury in mice

Serious damage to short-term kidney function—known as acute kidney injury, or AKI—can be fatal and also increase the risk of irreversible chronic kidney disease. It can be triggered by stressors ranging from sepsis to ...

Blocking gene improves metabolic health in obese mice without weight loss

Weill Cornell Medicine investigators have identified an early step in a cellular process that leads to inflammation in fat cells and may result in type 2 diabetes in people with obesity.

Sleep-related disorders associated with hypertension in postmenopausal women

Postmenopausal women are especially vulnerable to hypertension, which is a major cardiovascular risk factor. Women transitioning through or past the menopause transition are also more likely to report sleep disturbances (shorter ...

Nutritional supplement could help with fat metabolism activation therapies

Dr. Ann Coulter of Pennington Biomedical Research Center recently presented research on a novel nutritional supplement that targets fat cells to stimulate weight loss at the Bio on the Bayou conference in New Orleans.

Lactulose and tai chi show promise preventing falls for cirrhosis patients

Lactulose and tai chi can prevent falls in patients with cirrhosis, according to results from the LiveSMART Trial. Michigan Medicine hepatologists reported the findings as a late breaking abstract at The Liver Meeting 2025 ...

The flexible brain: How circuit excitability and plasticity shift across the day

Our brains do not react in a fixed, mechanical way like electronic circuits. Even if we see the same scene every day on our commute to work, what we feel—and whether it leaves a lasting impression—depends on our internal ...

Estrogen's role in boosting dopamine and cognition: Experiments uncover how hormones influence learning

Researchers have long established that hormones significantly affect the brain, creating changes in emotion, energy levels, and decision-making. However, the intricacies of these processes are not well understood.

Cutting key amino acids from mouse diets triggers weight loss through heat burning

It's not pleasant to shiver from the cold, but for some, it has the appeal of making the body burn more energy as heat than when staying in a warmer environment. According to several studies, exposure to cold is a reliable ...

Urolithin A nudges aging immune cells toward a youthful profile in 28 days

An international research team focused on aging reports that urolithin A at 1,000 mg per day shifted human immune profiles toward a more naive-like, less exhausted CD8+ state and increased fatty acid oxidation capacity, with ...

Why morning exercise feels so hard

Your alarm goes off. Somehow you manage to get dressed, drag yourself to the gym, and start squatting.

Routine use of metabolic drug recommended for all kidney function levels

The results of two large-scale studies demonstrate that sodium-glucose co-transporter 2 (SGLT2) inhibitors significantly reduce the risk of kidney disease progression, hospitalization, and death in people with and without ...

Q&A: Managing menopause after cancer

Menopause can bring a wave of physical and emotional changes—and for people with cancer, those changes can start earlier or feel more intense. Treatments like chemotherapy, radiation, surgery, and/or endocrine therapy can ...

Widely used pesticides may lower sperm count

Contemporary agricultural practices make it difficult to prevent consuming chemicals and potentially causing harm to the body.

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