Medical Journal March 8, 2023

Published Date: 10 Mar 2023

Today's top news includes: Salt-sensitive hypertension is common in women of all ages and genders...

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Latest News

Beyond Blood Sugar: Reframing Diabetes Awareness Through the Lens of Obesity

Beyond Blood Sugar: Reframing Diabetes Awareness Through the Lens of Obesity

Semaglutide Provides Cardiorenal Benefits in CKD With or Without Diabetes

Semaglutide Provides Cardiorenal Benefits in CKD With or Without Diabetes

Novo Nordisk’s Amycretin Demonstrates Superior Weight Loss Versus Placebo

Novo Nordisk’s Amycretin Demonstrates Superior Weight Loss Versus Placebo

Investigative Amylin Agonist Eloralintide Proves Superiority to Placebo in Weight Management

Investigative Amylin Agonist Eloralintide Proves Superiority to Placebo in Weight Management

How painkillers can contribute to anemia in cancer patients

Researchers from the German Cancer Research Center and the University of Freiburg show how certain painkillers influence the iron metabolism of liver cancer cells and can thus contribute to iron deficiency and anemia in cancer ...

Evidence builds for disrupted mitochondria as cause of Parkinson's

For decades, scientists have known that mitochondria, which produce energy inside our cells, malfunction in Parkinson's disease. But a critical question remained: do the failing mitochondria cause Parkinson's, or do they ...

Todays Updates

Nalbuphine Extended-Release Reduces Chronic Cough in IPF, with Philip Molyneaux, MBBS Philip Molyneaux, MBBS

New Phase 2 Trial to Test TREM2-Stabilizing Agent VHB937 in Alzheimer Disease Marco Meglio

A phase 2 study at CTAD 2025 explores VHB937's potential in treating early Alzheimer disease, focusing on safety and efficacy in patients.

MRI Analysis Shows Stem Cell Therapy Laromestrocel Reduced Neuroinflammation in Mild Alzheimer Disease Isabella Ciccone, MPH

In an analysis of the phase 2a CLEAR MIND study presented at CTAD 2025, laromestrocel treatment was associated with reduced hippocampal neuroinflammation in patients with mild Alzheimer disease.

Phase 3 Trial to Uncover Therapeutic Potential of 5-HT6 Antagonist Masupirdine to Treat Alzheimer Agitation Louie Pasculli

A new phase 3 clinical trial is underway to evaluate masupirdine, a selective 5-HT6 receptor antagonist, as a potential treatment for agitation in patients with Alzheimer’s disease.

Pulmonary Rehabilitation Reduces Type 2 Inflammation in High Inflammation Asthma

Pulmonary Rehabilitation Reduces Type 2 Inflammation in High Inflammation Asthma

Mental Health Apps Gain High Uptake but Struggle With Adherence, Retention

Mental Health Apps Gain High Uptake but Struggle With Adherence, Retention

6 Ophthalmology Headlines You Missed in October 2025

6 Ophthalmology Headlines You Missed in October 2025

Todays Updates

Nalbuphine Extended-Release Reduces Chronic Cough in IPF, with Philip Molyneaux, MBBS Philip Molyneaux, MBBS

New Phase 2 Trial to Test TREM2-Stabilizing Agent VHB937 in Alzheimer Disease Marco Meglio

A phase 2 study at CTAD 2025 explores VHB937's potential in treating early Alzheimer disease, focusing on safety and efficacy in patients.

MRI Analysis Shows Stem Cell Therapy Laromestrocel Reduced Neuroinflammation in Mild Alzheimer Disease Isabella Ciccone, MPH

In an analysis of the phase 2a CLEAR MIND study presented at CTAD 2025, laromestrocel treatment was associated with reduced hippocampal neuroinflammation in patients with mild Alzheimer disease.

Phase 3 Trial to Uncover Therapeutic Potential of 5-HT6 Antagonist Masupirdine to Treat Alzheimer Agitation Louie Pasculli

A new phase 3 clinical trial is underway to evaluate masupirdine, a selective 5-HT6 receptor antagonist, as a potential treatment for agitation in patients with Alzheimer’s disease.

Pulmonary Rehabilitation Reduces Type 2 Inflammation in High Inflammation Asthma

Pulmonary Rehabilitation Reduces Type 2 Inflammation in High Inflammation Asthma

Mental Health Apps Gain High Uptake but Struggle With Adherence, Retention

Mental Health Apps Gain High Uptake but Struggle With Adherence, Retention

6 Ophthalmology Headlines You Missed in October 2025

6 Ophthalmology Headlines You Missed in October 2025

Latest News

Beyond Blood Sugar: Reframing Diabetes Awareness Through the Lens of Obesity

Semaglutide Provides Cardiorenal Benefits in CKD With or Without Diabetes

Novo Nordisk’s Amycretin Demonstrates Superior Weight Loss Versus Placebo

Investigative Amylin Agonist Eloralintide Proves Superiority to Placebo in Weight Management

Researchers from the German Cancer Research Center and the University of Freiburg show how certain painkillers influence the iron metabolism of liver cancer cells and can thus contribute to iron deficiency and anemia in cancer ...

For decades, scientists have known that mitochondria, which produce energy inside our cells, malfunction in Parkinson's disease. But a critical question remained: do the failing mitochondria cause Parkinson's, or do they ...

News All Time

Sleep-related disorders associated with hypertension in postmenopausal women

Postmenopausal women are especially vulnerable to hypertension, which is a major cardiovascular risk factor. Women transitioning through or past the menopause transition are also more likely to report sleep disturbances (shorter ...

Lactulose and tai chi show promise preventing falls for cirrhosis patients

Lactulose and tai chi can prevent falls in patients with cirrhosis, according to results from the LiveSMART Trial. Michigan Medicine hepatologists reported the findings as a late breaking abstract at The Liver Meeting 2025 ...

Nutritional supplement could help with fat metabolism activation therapies

Dr. Ann Coulter of Pennington Biomedical Research Center recently presented research on a novel nutritional supplement that targets fat cells to stimulate weight loss at the Bio on the Bayou conference in New Orleans.

Early-life ketone signaling may shape long-term metabolic health

In a major advance in metabolic research, scientists from National Taiwan University have discovered that ketone bodies produced naturally during the lactation period are not merely an alternative fuel, but act as powerful ...

Blocking gene improves metabolic health in obese mice without weight loss

Weill Cornell Medicine investigators have identified an early step in a cellular process that leads to inflammation in fat cells and may result in type 2 diabetes in people with obesity.

Experimental drug protects mitochondria and prevents kidney injury in mice

Serious damage to short-term kidney function—known as acute kidney injury, or AKI—can be fatal and also increase the risk of irreversible chronic kidney disease. It can be triggered by stressors ranging from sepsis to ...

New study identifies overlooked tool for menopause symptom relief

A new study from the Kinsey Institute at Indiana University, published in the journal Menopause, finds self-pleasure is a valuable care strategy for managing menopause symptoms, especially mood and sleep changes. Most women ...

The flexible brain: How circuit excitability and plasticity shift across the day

Our brains do not react in a fixed, mechanical way like electronic circuits. Even if we see the same scene every day on our commute to work, what we feel—and whether it leaves a lasting impression—depends on our internal ...

Estrogen's role in boosting dopamine and cognition: Experiments uncover how hormones influence learning

Researchers have long established that hormones significantly affect the brain, creating changes in emotion, energy levels, and decision-making. However, the intricacies of these processes are not well understood.

Cutting key amino acids from mouse diets triggers weight loss through heat burning

It's not pleasant to shiver from the cold, but for some, it has the appeal of making the body burn more energy as heat than when staying in a warmer environment. According to several studies, exposure to cold is a reliable ...

Routine use of metabolic drug recommended for all kidney function levels

The results of two large-scale studies demonstrate that sodium-glucose co-transporter 2 (SGLT2) inhibitors significantly reduce the risk of kidney disease progression, hospitalization, and death in people with and without ...

Why morning exercise feels so hard

Your alarm goes off. Somehow you manage to get dressed, drag yourself to the gym, and start squatting.

Urolithin A nudges aging immune cells toward a youthful profile in 28 days

An international research team focused on aging reports that urolithin A at 1,000 mg per day shifted human immune profiles toward a more naive-like, less exhausted CD8+ state and increased fatty acid oxidation capacity, with ...

Widely used pesticides may lower sperm count

Contemporary agricultural practices make it difficult to prevent consuming chemicals and potentially causing harm to the body.

Q&A: Managing menopause after cancer

Menopause can bring a wave of physical and emotional changes—and for people with cancer, those changes can start earlier or feel more intense. Treatments like chemotherapy, radiation, surgery, and/or endocrine therapy can ...

Urinary albumin-creatinine ratio better measures risk for kidney failure

The urinary albumin-creatinine ratio (UACR) is more strongly associated with kidney failure than the urinary protein-creatinine ratio (UPCR), according to research published online Nov. 4 in the Annals of Internal Medicine.

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