Long-term running data not associated with arthritis risk: The marathon study

Published Date: 17 Mar 2023

A group of researchers from the annual meeting of the American Academy of Orthopedic Surgeons (AAOS) "analyzed the data and...

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Enzyme provides promising path to degenerative joint diseases cure

Degenerative joint diseases like osteoarthritis and intervertebral disk degeneration are conditions that affect millions of people worldwide, leading to pain and reduced mobility. These diseases remain incurable because current ...

New points to consider in treatment-resistant psoriatic arthritis

Some people with psoriatic arthritis (PsA) may have a disease that is difficult to manage (D2M) or does not respond to treatment. EULAR—The European Alliance of Associations for Rheumatology—has released new evidence-based ...

Study finds improvement in knee pain with exercise and physical therapy

People with a meniscal tear and osteoarthritis prescribed home exercises with or without physical therapy reported substantial improvements in knee pain, according to a new study led by Mass General Brigham researchers.

New genetic marker could improve prediction of severe gout drug reactions in US patients

A newly identified genetic marker may significantly improve the ability to predict life-threatening reactions to the gout medication allopurinol in U.S. patients.

SGLT-2 inhibitors tied to lower risk for autoimmune rheumatic diseases in adults with type 2 diabetes

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Simple screening tool can help uncover underdiagnosed back condition, study finds

For millions of people living with back pain, the cause is often elusive. One underrecognized culprit is axial spondyloarthritis (axSpA)—a form of inflammatory arthritis that primarily affects the spine and sacroiliac joints ...

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Phase 3b RESHAPE Study Evaluates Risk–Benefit of Switching From Ocrelizumab to BTK Inhibitor Remibrutinib Isabella Ciccone, MPH

A phase 3b study presented at ACTRIMS 2026 is evaluating whether switching to remibrutinib offers efficacy and safety comparable to continued ocrelizumab treatment in relapsing multiple sclerosis.

Todays Updates

Phase 3b RESHAPE Study Evaluates Risk–Benefit of Switching From Ocrelizumab to BTK Inhibitor Remibrutinib Isabella Ciccone, MPH

A phase 3b study presented at ACTRIMS 2026 is evaluating whether switching to remibrutinib offers efficacy and safety comparable to continued ocrelizumab treatment in relapsing multiple sclerosis.

Latest News

Degenerative joint diseases like osteoarthritis and intervertebral disk degeneration are conditions that affect millions of people worldwide, leading to pain and reduced mobility. These diseases remain incurable because current ...

Some people with psoriatic arthritis (PsA) may have a disease that is difficult to manage (D2M) or does not respond to treatment. EULAR—The European Alliance of Associations for Rheumatology—has released new evidence-based ...

People with a meniscal tear and osteoarthritis prescribed home exercises with or without physical therapy reported substantial improvements in knee pain, according to a new study led by Mass General Brigham researchers.

A newly identified genetic marker may significantly improve the ability to predict life-threatening reactions to the gout medication allopurinol in U.S. patients.

Sodium-glucose cotransporter-2 (SGLT-2) inhibitors are associated with a reduced risk for autoimmune rheumatic diseases compared with sulfonylureas among adults with type 2 diabetes, according to a study published online ...

For millions of people living with back pain, the cause is often elusive. One underrecognized culprit is axial spondyloarthritis (axSpA)—a form of inflammatory arthritis that primarily affects the spine and sacroiliac joints ...

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Seven-year study reveals rheumatoid arthritis begins long before symptoms, opening door to prevention 

Scientists have discovered that rheumatoid arthritis (RA) doesn't start when the pain begins. It silently starts years earlier. RA is a debilitating autoimmune disease that causes painful joint inflammation and damage. The ...

Self-guided online program improves quality of life in rheumatoid arthritis, psoriatic arthritis and lupus

Patients with rheumatoid arthritis, psoriatic arthritis, and systemic lupus erythematosus frequently face anxiety and depression along with chronic physical symptoms. Reported rates of depression range from 15% to 24% and ...

Analysis isolates population aging as primary driver of musculoskeletal disorders

Novel research shows that in approximately one third of countries and territories worldwide, population aging was the largest contributor to the growing burden of musculoskeletal disorders from 1990 to 2021.

Tirzepatide found to be more cost-effective than semaglutide in patients with knee osteoarthritis, obesity

A microsimulation model was used to evaluate the cost-effectiveness of two glucagon-like peptide-1 receptor agonists (GLP1RAs), semaglutide and tirzepatide, for patients with osteoarthritis and obesity compared with usual ...

Current research may open doors to new treatments for children with juvenile dermatomyositis

Children with a rare, debilitating muscle disease could benefit from the findings of new research by experts at UCL and Great Ormond Street Hospital (GOSH).

Squishy 'smart cartilage' could target arthritis pain as soon as flareups begin

Researchers have developed a material that can sense tiny changes within the body, such as during an arthritis flareup, and release drugs exactly where and when they are needed.

Immune aging may be a driver of rheumatoid arthritis rather than a consequence

Features of immune system aging can be detected in the earliest stages of rheumatoid arthritis (RA), even before clinical diagnosis, a new study has found which provides at-risk individuals with hope for early intervention.

Common arthritis drug found to lower blood pressure and risk of heart disease

Methotrexate, a common medication used to treat rheumatoid arthritis, has a newly recognized useful secondary effect of lowering blood pressure and potentially reduces the risk of heart disease in people with this condition.

Noisy knees not an early arthritis sign, says new study

Knee crepitus, the sound of cracking or grinding in the knee joint, is very common across all age groups.

Q&A: These genetic insights into rheumatoid arthritis could help design better treatments

People with rheumatoid arthritis (RA) often have trouble getting out of bed in the morning, let alone getting to the rheumatologist for a checkup or participating in a research study. This makes a deeper understanding of ...

Benefits of long-term routine lab drug toxicity monitoring unclear in rheumatoid arthritis

For patients with rheumatoid arthritis (RA) using disease-modifying antirheumatic drugs (DMARDs), long-term routine laboratory toxicity monitoring (lt-RLTM) indicates that most very abnormal laboratory results are already ...

Back pain a $638 billion productivity black hole, Australian study warns

A new study from Monash University has revealed that long-term back problems will cost the Australian economy an estimated $638 billion in lost productivity over the next decade unless urgent action is taken.

Survey reveals people are not aware knee and groin pain can be signs of hip problems

Having a hard time bending over to put your shoes on? Experiencing pain in the knees, groin, thigh or back? A survey by The Ohio State University Wexner Medical Center reveals many people don't realize these symptoms can ...

Improving prediction of worsening knee osteoarthritis with an AI-assisted model

An artificial intelligence (AI)-assisted model that combines a patient's MRI, biochemical, and clinical information shows preliminary promise in improving predictions of whether their knee osteoarthritis may soon worsen. ...

Scientist uncover hidden immune 'hubs' that drive joint damage in rheumatoid arthritis

Rheumatoid arthritis (RA) is an autoimmune disease that affects millions worldwide and can have a devastating impact on patients' lives. Yet, about one in three patients respond poorly to existing treatments.

Lupus low disease activity state attainable in lupus nephritis

In lupus nephritis, attainment of complete renal response (CRR)/partial renal response (PRR) and lupus low disease activity state (LLDAS) is associated with best relapse-free survival, with independent associations seen with ...

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