How does ChatGPT work? And its creator? Are you ready to cooperate with the vaccine?

Published Date: 16 Feb 2023

Chatbots have shields to control misinformation, but it will continue to be a game.

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New Tool Detects Alcohol in Steatotic Liver Disease

A simple new index may quantify the role of alcohol in steatotic liver disease without expensive testing.

The Fascinating Phenomenon That Is Your Brain on Exercise

A cascade of beneficial effects hits the brain during exercise — with new data on strength training. Helping your patients understand it can be a powerful motivator.

Facilitated Cascade Genetic Testing: A New Standard of Care?

A clinician-led approach boosts genetic testing among relatives of people with newly detected pathogenic variants — and could help close a gap in hereditary cancer prevention.

Positive Age Beliefs Linked to Functional Gains

Using Health and Retirement Study data, 31.9% show cognitive gains, and 28% improve gait speed over follow-up — findings that challenge the assumption that decline is inevitable.

Can We Agree on Fetal Growth Restriction Criteria?

Major international and national guidelines on fetal growth restriction (FGR) converge on surveillance and preterm interventions but diverge substantially on how FGR is defined.

Pollution, Poverty, May Age the Brain as Much as AD

Combined and cumulative physical and social environmental exposure may be more closely linked to brain aging than a clinical diagnosis such as Alzheimer’s Disease or MCI, a new study shows.

Todays Updates

Early Tislelizumab May Boost PFS in Esophageal Cancer

For patients with locally advanced esophageal cancer, front-loading immunotherapy with induction chemo and chemoradiotherapy, without maintenance immunotherapy, may improve outcomes.

ctDNA Predicts Relapse in Locally Advanced Cervical Cancer

Posttreatment ctDNA positivity correlates with worse relapse-free survival and earlier recurrence in patients with locally advanced cervical cancer, real-world data show.

GLP-1 RAs May Lower Hysterectomy Risk in Endometrial Cancer

There’s now a hint that GLP-1 receptor agonists might prevent hysterectomies in endometrial intraepithelial neoplasia/early-stage endometrial cancer, but prospective trials are needed to confirm it.

Todays Updates

Early Tislelizumab May Boost PFS in Esophageal Cancer

For patients with locally advanced esophageal cancer, front-loading immunotherapy with induction chemo and chemoradiotherapy, without maintenance immunotherapy, may improve outcomes.

ctDNA Predicts Relapse in Locally Advanced Cervical Cancer

Posttreatment ctDNA positivity correlates with worse relapse-free survival and earlier recurrence in patients with locally advanced cervical cancer, real-world data show.

GLP-1 RAs May Lower Hysterectomy Risk in Endometrial Cancer

There’s now a hint that GLP-1 receptor agonists might prevent hysterectomies in endometrial intraepithelial neoplasia/early-stage endometrial cancer, but prospective trials are needed to confirm it.

Latest News

A simple new index may quantify the role of alcohol in steatotic liver disease without expensive testing.

A cascade of beneficial effects hits the brain during exercise — with new data on strength training. Helping your patients understand it can be a powerful motivator.

A clinician-led approach boosts genetic testing among relatives of people with newly detected pathogenic variants — and could help close a gap in hereditary cancer prevention.

Using Health and Retirement Study data, 31.9% show cognitive gains, and 28% improve gait speed over follow-up — findings that challenge the assumption that decline is inevitable.

Major international and national guidelines on fetal growth restriction (FGR) converge on surveillance and preterm interventions but diverge substantially on how FGR is defined.

Combined and cumulative physical and social environmental exposure may be more closely linked to brain aging than a clinical diagnosis such as Alzheimer’s Disease or MCI, a new study shows.

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CAR T-Cell Therapy Tied to Better Survival in Relapsed LBCL

A single-center real-world study compares the effectiveness and toxicity of chimeric antigen receptor T-cell therapy vs historical care for relapsed or refractory LBCL.

Medical Use of Cannabis Poses Risks in Adolescents

Adolescents who use cannabis on a medical recommendation report more frequent use of cannabis and other substances than peers who use the drug without a medical recommendation.

TB Today: Short-Course, Long Problems

Antibiotics transform TB care, but without stable health systems, housing improvements, and poverty reduction, the disease persists — medicine alone cannot end TB.

AI Chatbot Prescribing Psychiatric Meds Raises Red Flags

A pilot program that will allow a chatbot to authorize select psychiatric prescription refills while state regulators suspend enforcement of some licensure rules is raising legal and safety concerns.

AI and Medical Errors: Who Takes the Blame Now?

AI use in clinical care raises unresolved liability questions, with clinicians retaining responsibility as evolving technology and legal frameworks continue to blur accountability.

PrEP Use ‘Strikingly Low’ in People Younger Than 25

More training may be needed for health professionals, including pediatricians, to increase prescribing to teens.

Is the Viral Plastic Diet Linked to Eating Disorder Risk?

A viral plastic diet trend raises concerns for choking, metabolic disruption, and increased risk for eating disorders among youth.

How the Gulf Crisis Is Reaching Europe’s Pharmacies

Conflict in the Gulf is exposing how dependent Europe’s pharmacies are on global supply chains for essential medicines, active ingredients, and transport.

The Flaws in the New HHS Nutrition Education Initiative

Doctors aren't dietitians. Fantuzzi and Straughan unpack the flaws in the new HHS nutrition competencies and advocate for collaborative care.

Acute Severe Ulcerative Colitis: 10 Risks in Older Adults

Older adults with acute severe ulcerative colitis have higher mortality, underscoring the need for targeted strategies to reduce the risk for adverse events and enable timely treatment decisions.

Antidepressant Promising for Methamphetamine Addiction

There are no approved medications for methamphetamine use disorder, but phase 3 trial results suggest the generic antidepressant mirtazapine may offer modest but significant reductions in use.

Proximity to Nuclear Plants Linked to Cancer Mortality

A US ecologic study finds higher cancer mortality in counties closer to nuclear plants, but results reflect association and require cautious clinical interpretation.

Modern Breast Radiation Shows Minimal Heart Risks

Modern techniques have greatly reduced the heart disease risks historically tied to radiotherapy for left-sided breast cancer, a large cohort study suggests.

Social Risks Linked to Higher Spending on Healthcare

Certain social risk factors are linked to higher costs of healthcare among patients.

Depression, Delirium May Signal Supranuclear Palsy Risk

Depression, delirium, gastrointestinal disorders, and heavy alcohol consumption are modifiable risk factors for progressive supranuclear palsy, a new study shows.

Hypnotic Therapy Tied to Reduced Spinal Cord Injury Pain

Hypnotic cognitive therapy is associated with greater reductions in chronic pain and depression than usual care in patients with spinal cord injury, a new study shows.

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Clinical Evidence Shows Venetoclax Combo Is Safe and Effective in AML Patients 80 Years of Age and Up.

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